NTDB

Overview

Name	endA	Type	Machinery gene
Locus tag	QLH56_RS09580	Genome accession	NZ_CP125107
Coordinates	1976988..1977851 (+)	Length	287 a.a.
NCBI ID	WP_003099993.1	Uniprot ID	A0A3L8GIC3
Organism	Streptococcus iniae strain DFSM220524
Function	cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1971988..1982851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QLH56_RS09550 (QLH56_09550)	-	1972290..1973165 (+)	876	WP_003100004.1	F0F1 ATP synthase subunit gamma	-
QLH56_RS09555 (QLH56_09555)	atpD	1973281..1974687 (+)	1407	WP_003100002.1	F0F1 ATP synthase subunit beta	-
QLH56_RS09560 (QLH56_09560)	-	1974700..1975116 (+)	417	WP_003100001.1	F0F1 ATP synthase subunit epsilon	-
QLH56_RS09565 (QLH56_09565)	-	1975192..1975428 (+)	237	WP_071794729.1	DUF1146 family protein	-
QLH56_RS09570 (QLH56_09570)	murA	1975494..1976765 (+)	1272	WP_003099997.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
QLH56_RS09575 (QLH56_09575)	-	1976769..1976957 (+)	189	WP_003099995.1	DNA-directed RNA polymerase subunit beta	-
QLH56_RS09580 (QLH56_09580)	endA	1976988..1977851 (+)	864	WP_003099993.1	DNA/RNA non-specific endonuclease	Machinery gene
QLH56_RS09585 (QLH56_09585)	pheS	1978143..1979186 (+)	1044	WP_003099992.1	phenylalanine--tRNA ligase subunit alpha	-
QLH56_RS09590 (QLH56_09590)	-	1979199..1979723 (+)	525	WP_003099991.1	N-acetyltransferase	-
QLH56_RS09595 (QLH56_09595)	pheT	1979739..1982144 (+)	2406	WP_003099989.1	phenylalanine--tRNA ligase subunit beta	-
QLH56_RS09600 (QLH56_09600)	-	1982217..1982597 (+)	381	WP_003099988.1	OsmC family protein	-

Sequence

Protein

Download Length: 287 a.a. Molecular weight: 31715.35 Da Isoelectric Point: 9.3865

                                >NTDB_id=829990 QLH56_RS09580 WP_003099993.1 1976988..1977851(+) (endA) [Streptococcus iniae strain DFSM220524]

MSPKTKQSQKINLLLFLLVLVGLFYLIDSKEGEENNPIRAFYQSVMGASNQTSQKESSNPDTPSYALASSVLTEKVKRQL

GSKVEWNGNGAFVINDNSTNLDAKVSSAPYAHNQTRLLSGKKLPTVANALLAKSTRQYRDRNETGNGYSYWKPAGWHQIH

GLSGKYDHAVDRGHLLGYALVGGLKGFDASTSNSDNIATQLSWANQAMDSDSTGQNYYETKIRRALDKNKRVRYRVTLIY

EADNILASGSHLEAKSDDGSLEFNVFVPNVQKGLEVDYQTGQITVSH

Nucleotide

Download Length: 864 bp

                                >NTDB_id=829990 QLH56_RS09580 WP_003099993.1 1976988..1977851(+) (endA) [Streptococcus iniae strain DFSM220524]

ATGTCACCAAAGACAAAACAAAGTCAAAAAATCAATCTATTATTGTTTCTGCTTGTGCTCGTTGGCTTATTCTATTTGAT

TGATAGTAAAGAAGGGGAAGAGAATAATCCTATTCGAGCCTTTTATCAATCAGTGATGGGAGCTTCCAATCAAACTAGCC

AAAAAGAATCAAGCAATCCTGATACACCAAGTTATGCCTTGGCATCTTCGGTTTTAACAGAAAAAGTAAAAAGACAACTT

GGTTCGAAAGTTGAGTGGAATGGTAATGGTGCATTTGTCATCAATGATAACAGTACCAATTTGGATGCAAAAGTATCCAG

TGCTCCCTATGCTCACAATCAAACCAGACTCTTATCAGGGAAAAAGCTTCCAACAGTCGCCAATGCTTTACTTGCCAAAT

CAACAAGGCAATACCGAGACCGAAACGAGACCGGAAATGGCTACTCTTATTGGAAACCTGCTGGTTGGCACCAGATTCAT

GGTTTATCAGGAAAATATGATCACGCTGTGGACCGTGGGCATTTATTAGGCTATGCTTTAGTGGGAGGTCTTAAAGGATT

TGATGCCTCTACAAGCAATAGCGATAACATAGCAACGCAATTATCCTGGGCTAACCAAGCGATGGATAGTGATTCCACTG

GCCAAAATTATTATGAAACAAAAATCAGACGTGCATTGGACAAGAATAAGCGTGTCCGTTACCGTGTTACCCTCATTTAC

GAGGCTGATAATATATTAGCAAGTGGAAGCCATTTAGAAGCAAAATCAGATGACGGCAGTTTAGAATTTAACGTTTTTGT

GCCAAATGTTCAAAAAGGTCTAGAAGTTGACTATCAAACAGGACAAATAACAGTCAGTCACTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(95-245)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A3L8GIC3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
endA	Streptococcus pneumoniae Rx1	63.559	82.23	0.523
endA	Streptococcus pneumoniae D39	63.559	82.23	0.523
endA	Streptococcus pneumoniae R6	63.559	82.23	0.523
endA	Streptococcus pneumoniae TIGR4	63.559	82.23	0.523

Detailed information NTG0829990