Detailed information NTG0082843

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: H7676_RS03595
• Genome accession: NZ_AP023390
• Coordinates: 710130..711359 (+)
• Length: 409 a.a.
• NCBI ID: WP_031488352.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain KUN-0014944
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 705130..716359

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7676_RS03575 (KUN4944_06600)	-	705746..707023 (-)	1278	WP_184492320.1	hydroxymethylglutaryl-CoA reductase, degradative	-
H7676_RS03580 (KUN4944_06610)	-	707010..708185 (-)	1176	WP_031488354.1	hydroxymethylglutaryl-CoA synthase	-
H7676_RS03585 (KUN4944_06620)	-	708394..709233 (+)	840	WP_011017679.1	thymidylate synthase	-
H7676_RS03590 (KUN4944_06630)	-	709313..709810 (+)	498	WP_031488353.1	dihydrofolate reductase	-
H7676_RS03595 (KUN4944_06650)	clpX	710130..711359 (+)	1230	WP_031488352.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
H7676_RS03600 (KUN4944_06660)	yihA	711369..711968 (+)	600	WP_002990160.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
H7676_RS03605 (KUN4944_06670)	-	712116..712859 (+)	744	WP_002984942.1	hypothetical protein	-
H7676_RS03610 (KUN4944_06680)	-	712917..715016 (-)	2100	WP_031488351.1	AAA family ATPase	-
H7676_RS03615 (KUN4944_06690)	rpiA	715394..716077 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44991.48 Da
• Isoelectric Point: 4.6184

>NTDB_id=82843 H7676_RS03595 WP_031488352.1 710130..711359(+) (clpX) [Streptococcus pyogenes strain KUN-0014944]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIKI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=82843 H7676_RS03595 WP_031488352.1 710130..711359(+) (clpX) [Streptococcus pyogenes strain KUN-0014944]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGTCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTTTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTAAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.242	100	0.892
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575