Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   QFX46_RS03515 Genome accession   NZ_CP123739
Coordinates   706705..707421 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain 2.5     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 701705..712421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX46_RS03495 - 702797..703747 (+) 951 WP_000790326.1 LacI family DNA-binding transcriptional regulator -
  QFX46_RS03500 - 703896..705380 (+) 1485 WP_000141435.1 sucrose-6-phosphate hydrolase -
  QFX46_RS03505 - 705377..706336 (+) 960 WP_001253302.1 carbohydrate kinase -
  QFX46_RS03510 - 706524..706633 (-) 110 Protein_687 hypothetical protein -
  QFX46_RS03515 agrA 706705..707421 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  QFX46_RS03520 agrC 707440..708732 (-) 1293 WP_304984529.1 quorum-sensing sensor histidine kinase AgrC -
  QFX46_RS03525 agrD 708757..708897 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  QFX46_RS03530 agrB 708894..709463 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  QFX46_RS03535 hld 709753..709833 (+) 81 WP_000046022.1 delta-hemolysin -
  QFX46_RS03540 - 710433..711218 (-) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  QFX46_RS03545 - 711579..712205 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=822002 QFX46_RS03515 WP_000688498.1 706705..707421(-) (agrA) [Staphylococcus aureus strain 2.5]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=822002 QFX46_RS03515 WP_000688498.1 706705..707421(-) (agrA) [Staphylococcus aureus strain 2.5]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996