Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   QFX10_RS07020 Genome accession   NZ_CP123639
Coordinates   1545526..1546350 (+) Length   274 a.a.
NCBI ID   WP_280605543.1    Uniprot ID   -
Organism   Ligilactobacillus faecis strain WILCCON 0062     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1546706..1585123 1545526..1546350 flank 356


Gene organization within MGE regions


Location: 1545526..1585123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX10_RS07020 (QFX10_07020) endA 1545526..1546350 (+) 825 WP_280605543.1 DNA/RNA non-specific endonuclease Machinery gene
  QFX10_RS07025 (QFX10_07025) - 1546358..1546669 (+) 312 WP_280605544.1 MazG-like protein -
  QFX10_RS07030 (QFX10_07030) - 1546706..1548373 (-) 1668 WP_280605405.1 IS1182 family transposase -
  QFX10_RS07035 (QFX10_07035) - 1548552..1548899 (-) 348 WP_280605545.1 DUF4828 domain-containing protein -
  QFX10_RS07040 (QFX10_07040) - 1549382..1550401 (+) 1020 WP_280605546.1 Gfo/Idh/MocA family protein -
  QFX10_RS07045 (QFX10_07045) - 1550426..1551682 (+) 1257 WP_280605547.1 DEAD/DEAH box helicase -
  QFX10_RS07050 (QFX10_07050) - 1551798..1552211 (+) 414 WP_280605548.1 DUF3284 domain-containing protein -
  QFX10_RS07060 (QFX10_07060) - 1552591..1553952 (+) 1362 WP_280605549.1 ISL3 family transposase -
  QFX10_RS07065 (QFX10_07065) - 1554261..1555109 (-) 849 WP_280605550.1 LysR family transcriptional regulator -
  QFX10_RS07070 (QFX10_07070) - 1555322..1555994 (+) 673 Protein_1336 IS607 family transposase -
  QFX10_RS07075 (QFX10_07075) - 1555933..1557087 (+) 1155 WP_280605551.1 transposase -
  QFX10_RS07080 (QFX10_07080) - 1557356..1558396 (+) 1041 WP_280605552.1 zinc-dependent alcohol dehydrogenase family protein -
  QFX10_RS07085 (QFX10_07085) - 1558513..1559121 (+) 609 WP_280605553.1 class I SAM-dependent methyltransferase -
  QFX10_RS07090 (QFX10_07090) tadA 1559114..1559572 (+) 459 WP_280605554.1 tRNA adenosine(34) deaminase TadA -
  QFX10_RS07100 (QFX10_07100) dnaX 1559794..1561524 (+) 1731 WP_280605555.1 DNA polymerase III subunit gamma/tau -
  QFX10_RS07105 (QFX10_07105) - 1561544..1561858 (+) 315 WP_280607253.1 YbaB/EbfC family nucleoid-associated protein -
  QFX10_RS07110 (QFX10_07110) recR 1561881..1562480 (+) 600 WP_280605556.1 recombination mediator RecR -
  QFX10_RS07115 (QFX10_07115) - 1562496..1562735 (+) 240 WP_280605557.1 YaaL family protein -
  QFX10_RS07120 (QFX10_07120) tmk 1562833..1563483 (+) 651 WP_280605558.1 dTMP kinase -
  QFX10_RS07125 (QFX10_07125) - 1563484..1563810 (+) 327 WP_280605559.1 cyclic-di-AMP receptor -
  QFX10_RS07130 (QFX10_07130) holB 1563869..1564864 (+) 996 WP_280605560.1 DNA polymerase III subunit delta' -
  QFX10_RS07135 (QFX10_07135) - 1564880..1565230 (+) 351 WP_280605561.1 DNA replication initiation control protein YabA -
  QFX10_RS07140 (QFX10_07140) rsmI 1565230..1566123 (+) 894 WP_280605562.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  QFX10_RS07145 (QFX10_07145) - 1566124..1566867 (+) 744 WP_280605563.1 acyl-[acyl-carrier-protein] thioesterase -
  QFX10_RS07150 (QFX10_07150) - 1566945..1567925 (-) 981 WP_280605564.1 asparaginase -
  QFX10_RS07155 (QFX10_07155) tsaB 1568128..1568853 (+) 726 WP_280605565.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB -
  QFX10_RS07160 (QFX10_07160) - 1568828..1569448 (+) 621 WP_280605566.1 GNAT family N-acetyltransferase -
  QFX10_RS07165 (QFX10_07165) tsaD 1569414..1570451 (+) 1038 WP_280605567.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD -
  QFX10_RS07170 (QFX10_07170) - 1570627..1571865 (+) 1239 WP_280605426.1 ISL3 family transposase -
  QFX10_RS07175 (QFX10_07175) - 1571929..1573499 (-) 1571 Protein_1356 IS3 family transposase -
  QFX10_RS07180 (QFX10_07180) - 1573637..1575589 (-) 1953 WP_280605568.1 ABC-F family ATP-binding cassette domain-containing protein -
  QFX10_RS07185 (QFX10_07185) - 1575813..1576445 (+) 633 WP_280605569.1 redox-sensing transcriptional repressor Rex -
  QFX10_RS07190 (QFX10_07190) - 1576503..1577132 (-) 630 WP_280605570.1 CPBP family intramembrane glutamic endopeptidase -
  QFX10_RS07195 (QFX10_07195) groES 1577331..1577615 (+) 285 WP_280605571.1 co-chaperone GroES -
  QFX10_RS07200 (QFX10_07200) groL 1577659..1579275 (+) 1617 WP_280605572.1 chaperonin GroEL -
  QFX10_RS07205 (QFX10_07205) - 1579440..1579574 (+) 135 WP_280605573.1 hypothetical protein -
  QFX10_RS07210 (QFX10_07210) - 1579675..1581212 (+) 1538 Protein_1363 IS3 family transposase -
  QFX10_RS07215 (QFX10_07215) - 1581381..1582112 (-) 732 WP_280605574.1 LytTR family DNA-binding domain-containing protein -
  QFX10_RS07220 (QFX10_07220) - 1582328..1582498 (+) 171 WP_280605575.1 hypothetical protein -
  QFX10_RS07225 (QFX10_07225) - 1583008..1585123 (+) 2116 Protein_1366 peptide cleavage/export ABC transporter -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 30119.92 Da        Isoelectric Point: 10.4907

>NTDB_id=821857 QFX10_RS07020 WP_280605543.1 1545526..1546350(+) (endA) [Ligilactobacillus faecis strain WILCCON 0062]
MKLKKILLSLAALFVLGGTLAPTTVQSETLASRRTHYYRSSSSQGTLKESTPSEQLARSVLTPTVVKQLGGEQNIKWNQH
GAFIINNDKTKLKAKVSSAPYATNTVDQLQRPTVANALLNKTTRQYKSREQTNNGSTSWRPQGFKQVTGLSGTYNHAYDR
GHLLGYALVGNIRGFDASESNPKNIATQTAWANEANARYSTGQNYYESLVRKALDKNKTVRYRVTNIYDGNALVPAGAHI
EAKASDGSLEYNVFIPNVQKGLKINYMTGQVTKG

Nucleotide


Download         Length: 825 bp        

>NTDB_id=821857 QFX10_RS07020 WP_280605543.1 1545526..1546350(+) (endA) [Ligilactobacillus faecis strain WILCCON 0062]
ATGAAGTTAAAAAAGATATTGTTGAGCTTAGCGGCACTCTTTGTGCTTGGAGGCACGTTAGCGCCAACGACAGTCCAAAG
TGAGACGCTTGCTAGTCGCAGAACGCATTACTATCGTTCGAGCAGTAGTCAAGGGACGCTCAAAGAGAGCACGCCTTCAG
AACAGCTGGCTCGTTCAGTTTTAACACCCACAGTCGTCAAACAACTTGGGGGCGAGCAAAATATCAAATGGAACCAACAC
GGAGCTTTTATCATCAATAATGATAAAACAAAACTGAAGGCTAAAGTATCCAGTGCACCGTATGCGACTAATACAGTCGA
TCAATTGCAACGACCGACAGTTGCTAACGCGCTTTTAAATAAAACGACACGCCAATATAAGAGTCGAGAACAGACCAACA
ATGGTTCGACTAGTTGGCGTCCTCAAGGTTTCAAGCAAGTTACCGGCCTGTCTGGAACGTATAATCACGCCTATGATCGG
GGACACTTGCTAGGTTACGCTCTTGTTGGGAATATTAGAGGTTTTGATGCTAGCGAGAGCAACCCTAAAAATATCGCGAC
TCAAACTGCCTGGGCCAATGAAGCCAATGCACGTTATTCAACAGGGCAAAACTATTATGAAAGTTTAGTTCGTAAAGCTT
TAGATAAAAATAAAACAGTGCGTTACCGCGTTACAAATATTTATGATGGAAATGCTTTAGTTCCAGCAGGCGCTCACATA
GAAGCGAAAGCTAGTGATGGTAGTTTAGAATACAATGTCTTTATCCCAAATGTACAAAAAGGCTTAAAGATCAACTATAT
GACTGGACAAGTAACAAAGGGGTGA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(83-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

63.248

85.401

0.54
  endA Streptococcus pneumoniae D39

63.248

85.401

0.54
  endA Streptococcus pneumoniae R6

63.248

85.401

0.54
  endA Streptococcus pneumoniae TIGR4

63.248

85.401

0.54