Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   R4701_RS08585 Genome accession   NZ_CP137114
Coordinates   1671033..1671821 (+) Length   262 a.a.
NCBI ID   WP_000940734.1    Uniprot ID   Q8DP01
Organism   Streptococcus pneumoniae strain 15P3054     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1666033..1676821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS08570 - 1666263..1667579 (-) 1317 WP_000958944.1 FAD-containing oxidoreductase -
  R4701_RS08575 - 1667770..1668996 (+) 1227 WP_000841578.1 OFA family MFS transporter -
  R4701_RS08580 - 1669195..1670769 (+) 1575 WP_000671113.1 DEAD/DEAH box helicase -
  R4701_RS08585 codY 1671033..1671821 (+) 789 WP_000940734.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  R4701_RS08590 - 1671821..1672396 (+) 576 WP_050254956.1 cysteine hydrolase family protein -
  R4701_RS08600 - 1672847..1673977 (+) 1131 WP_000229962.1 ABC transporter ATP-binding protein -
  R4701_RS08605 - 1674124..1674270 (-) 147 WP_000403100.1 hypothetical protein -
  R4701_RS08610 - 1674478..1675236 (+) 759 WP_001287242.1 class I SAM-dependent methyltransferase -
  R4701_RS08615 - 1675323..1675835 (+) 513 WP_001049323.1 adenine phosphoribosyltransferase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29756.11 Da        Isoelectric Point: 5.4646

>NTDB_id=820156 R4701_RS08585 WP_000940734.1 1671033..1671821(+) (codY) [Streptococcus pneumoniae strain 15P3054]
MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYV
QGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLISDIFEEVKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=820156 R4701_RS08585 WP_000940734.1 1671033..1671821(+) (codY) [Streptococcus pneumoniae strain 15P3054]
ATGGCACATTTATTAGAAAAAACTAGAAAAATTACATCAATTTTGAAACGCTCAGAGGAGCAGTTGCAGGATGAGCTCCC
TTACAACGCTATTACGCGTCAGTTAGCGGATATTATTCATTGCAATGCCTGCATTATCAATAGTAAGGGACGTCTGCTTG
GCTATTTTATGCGTTATAAAACAAATACAGATCGCGTAGAGCAATTCTTCCAAACTAAGATTTTCCCAGATGACTACGTT
CAAGGGGCTAATATGATTTACGAAACAGAAGCAAACTTGCCTGTTGAGCATGATATGAGTATTTTCCCTGTTGAGAGTAG
AGATGATTTTCCAGATGGCTTGACGACTATTGCACCGATTCATGTATCGGGGATTCGCCTTGGTTCTTTGATTATTTGGC
GTAATGATAAAAAATTCGAAGATGAGGACTTGGTTCTTGTTGAGATTGCCAGTACCGTTGTTGGGATTCAGCTTCTTAAC
TTCCAACGTGAAGAAGATGAGAAAAATATTCGTCGTCGTACTGCTGTCACCATGGCGGTCAATACCCTTTCTTACTCCGA
ACTCCGTGCTGTTTCAGCAATTTTAGGGGAATTAAATGGAAATGAAGGGCAGTTGACTGCGTCAGTGATTGCAGATCGTA
TCGGAATCACTCGCTCTGTGATTGTCAATGCTCTTCGTAAACTTGAGTCTGCGGGGATTATTGAAAGTCGCTCACTTGGA
ATGAAGGGAACCTATCTTAAGGTCTTGATTTCAGATATTTTTGAAGAAGTGAAGAAAAGAGATTACTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DP01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

62.595

100

0.626
  codY Bacillus subtilis subsp. subtilis str. 168

48.374

93.893

0.454