Detailed information NTG0818704

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY70_RS10365
• Genome accession: NZ_CP123099
• Coordinates: 2114084..2114971 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IT-MSSA55
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2109084..2119971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY70_RS10335 (QAY70_10330)	-	2109816..2110577 (+)	762	WP_000323447.1	alpha/beta hydrolase	-
QAY70_RS10340 (QAY70_10335)	-	2110822..2111277 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY70_RS10345 (QAY70_10340)	-	2111399..2111500 (+)	102	WP_000731972.1	SE2200 family small protein	-
QAY70_RS10350 (QAY70_10345)	-	2111560..2112984 (-)	1425	WP_000953762.1	alkaline phosphatase	-
QAY70_RS10355 (QAY70_10350)	-	2113182..2113382 (+)	201	WP_000604727.1	hypothetical protein	-
QAY70_RS10360 (QAY70_10355)	braR	2113408..2114073 (+)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY70_RS10365 (QAY70_10360)	braS	2114084..2114971 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY70_RS10370 (QAY70_10365)	-	2115080..2115835 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAY70_RS10375 (QAY70_10370)	-	2115832..2117832 (+)	2001	WP_000776739.1	ABC transporter permease	-
QAY70_RS10380 (QAY70_10375)	-	2118491..2118604 (+)	114	Protein_2007	hypothetical protein	-
QAY70_RS10385 (QAY70_10380)	-	2118986..2119246 (+)	261	WP_001789910.1	hypothetical protein	-
QAY70_RS10390 (QAY70_10385)	-	2119256..2119753 (+)	498	WP_001065269.1	glutathione peroxidase	-
QAY70_RS10395 (QAY70_10390)	-	2119861..2119953 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=818704 QAY70_RS10365 WP_000143420.1 2114084..2114971(+) (braS) [Staphylococcus aureus strain IT-MSSA55]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=818704 QAY70_RS10365 WP_000143420.1 2114084..2114971(+) (braS) [Staphylococcus aureus strain IT-MSSA55]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993