Detailed information NTG0081331

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: R8474_RS01590
• Genome accession: NZ_AP026914
• Coordinates: 299372..301477 (+)
• Length: 701 a.a.
• NCBI ID: WP_081573859.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700003
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 294372..306477

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8474_RS01570 (PC0003_03020)	rsmH	294415..295365 (+)	951	WP_000159402.1	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	-
R8474_RS01575 (PC0003_03030)	ftsL	295375..295692 (+)	318	WP_000227826.1	cell division protein FtsL	-
R8474_RS01580 (PC0003_03040)	pbp2X	295696..297948 (+)	2253	WP_081573857.1	penicillin-binding protein PBP2X	-
R8474_RS01585 (PC0003_03050)	mraY	297950..298930 (+)	981	WP_081573858.1	phospho-N-acetylmuramoyl-pentapeptide- transferase	-
R8474_RS01590 (PC0003_03060)	clpC	299372..301477 (+)	2106	WP_081573859.1	AAA family ATPase	Regulator
R8474_RS01595 (PC0003_03070)	-	301773..302255 (-)	483	WP_000032550.1	S-ribosylhomocysteine lyase	-
R8474_RS01600 (PC0003_03080)	-	302350..303834 (-)	1485	WP_000743611.1	DUF1846 domain-containing protein	-
R8474_RS01605 (PC0003_03090)	-	303987..305594 (+)	1608	WP_001156827.1	alpha-glucosidase	-
R8474_RS01610	-	305759..305926 (+)	168	WP_033607931.1	S-ribosylhomocysteinase	-
R8474_RS01615	-	305919..306440 (-)	522	Protein_315	transposase	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77531.37 Da
• Isoelectric Point: 4.7627

>NTDB_id=81331 R8474_RS01590 WP_081573859.1 299372..301477(+) (clpC) [Streptococcus pneumoniae strain PZ900700003]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAHYRATGQLPGNAEVDGKMPQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAKDTYKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPELLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKV

Nucleotide

• Length: 2106 bp

>NTDB_id=81331 R8474_RS01590 WP_081573859.1 299372..301477(+) (clpC) [Streptococcus pneumoniae strain PZ900700003]
ATGAACAACAACTTTAATAATTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATATAGTTC
TGAAAATCGCCGTTACTTGATTAATGGTCGTGAAGTGACACCTGAGGAATTTGCTCACTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAAGTTGATGGAAAAATGCCACAACAGGCATCAGGTATGAAGCAAGACGGTGTCCTTGCTAAACTGGGT
CGAAACTTGACAGCAGAAGCGCGTGAGGGCAAGCTGGATCCTGTTATCGGACGAAATAAGGAAATTCAAGAAACATCTGA
AATCCTTTCACGCCGTACCAAGAACAATCCTGTACTTGTCGGAGATGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGTT
TAGCACAAGCTATTGTGAATGGCGATGTTCCTGCTGCTATTAAGAATAAGGAAATTATTTCCATTGACATCTCAGGTCTT
GAGGCTGGGACTCAATATCGTGGTAGCTTTGAAGAAAATGTCCAAAACCTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATCCTTGGCGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGGCTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACGACTCAAGATGAATACCGTAATACCATC
TTGAAGAATGCAGCTCTTGCTCGTCGTTTCAACGAAGTCAAGGTCAATGCTCCTTCAGCAAAGGATACATATAAAATCCT
TCAAGGAATTCGTGATCTATATCAACAACACCACAATGTCATCTTGCCAGACGAAGTTTTGAAAGCAGCGGTGGATTATT
CTGTTCAGTATATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTTACGGCAGCTCACTTGGCAGCT
CAGCATCCTGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAAGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCCGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGCTGT
AGCTCGTGCTATCCGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAGCTTCCTCTTTGTAGGATCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGCTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGATCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCTTTCTTCCGTCCAGAACTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGTCTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (259-354)

• ATPase family associated with various cellular activities (AAA) (AAA) (118-250)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (610-680)

• AAA domain (Cdc48 subfamily) (AAA_2) (443-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	47.293	100	0.474
clpE	Streptococcus mutans UA159	49.065	91.583	0.449
clpE	Streptococcus pneumoniae TIGR4	47.792	90.442	0.432
clpE	Streptococcus pneumoniae Rx1	47.792	90.442	0.432
clpE	Streptococcus pneumoniae D39	47.792	90.442	0.432
clpE	Streptococcus pneumoniae R6	47.792	90.442	0.432
clpC	Bacillus subtilis subsp. subtilis str. 168	44.737	92.154	0.412
clpC	Streptococcus pneumoniae Rx1	42.654	90.3	0.385
clpC	Streptococcus pneumoniae D39	42.654	90.3	0.385
clpC	Streptococcus pneumoniae TIGR4	42.496	90.3	0.384
clpC	Streptococcus thermophilus LMD-9	42.54	89.872	0.382
clpC	Streptococcus thermophilus LMG 18311	42.381	89.872	0.381
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.95	88.017	0.378
clpC	Streptococcus mutans UA159	41.748	88.16	0.368