Detailed information NTG0081322

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: R8474_RS00235
• Genome accession: NZ_AP026914
• Coordinates: 40668..41561 (+)
• Length: 297 a.a.
• NCBI ID: WP_069288092.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700003
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 35668..46561

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8474_RS00195 (PC0003_00330)	-	35981..37150 (+)	1170	WP_000366376.1	pyridoxal phosphate-dependent aminotransferase	-
R8474_RS00200 (PC0003_00340)	recO	37147..37917 (+)	771	WP_000616164.1	DNA repair protein RecO	Machinery gene
R8474_RS00205 (PC0003_00350)	plsX	37914..38906 (+)	993	WP_000717462.1	phosphate acyltransferase PlsX	-
R8474_RS00210 (PC0003_00360)	-	38912..39145 (+)	234	WP_000136447.1	acyl carrier protein	-
R8474_RS00215 (PC0003_00370)	-	39182..39481 (+)	300	Protein_35	transposase family protein	-
R8474_RS00220 (PC0003_00380)	blpU	39684..39914 (+)	231	WP_050280078.1	bacteriocin-like peptide BlpU	-
R8474_RS00225	-	39917..40042 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
R8474_RS00230	-	40453..40647 (+)	195	WP_000756776.1	hypothetical protein	-
R8474_RS00235 (PC0003_00390)	comR	40668..41561 (+)	894	WP_069288092.1	XRE family transcriptional regulator	Regulator
R8474_RS00240 (PC0003_00400)	-	42091..42387 (+)	297	WP_000837726.1	uberolysin/carnocyclin family circular bacteriocin	-
R8474_RS00245	-	42394..43530 (+)	1137	WP_081573910.1	hypothetical protein	-
R8474_RS00250 (PC0003_00410)	-	43527..44009 (+)	483	WP_001232094.1	stage II sporulation protein M	-
R8474_RS00255 (PC0003_00420)	-	44006..44602 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
R8474_RS00260 (PC0003_00430)	-	44583..45074 (+)	492	WP_000671990.1	hypothetical protein	-

Sequence

Protein

• Length: 297 a.a.
• Molecular weight: 34543.10 Da
• Isoelectric Point: 4.6498

>NTDB_id=81322 R8474_RS00235 WP_069288092.1 40668..41561(+) (comR) [Streptococcus pneumoniae strain PZ900700003]
MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENGQALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFL
KLKDELIHSQTYADKGRIERKEAILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLILFIQIQTEDSLIYIQTFEKIIAKTRHVF
YRPHLFLLKAKYALFVDKNILEAESFYEKAISLAELLDDQVLVQRILAEKQIDFPTT

Nucleotide

• Length: 894 bp

>NTDB_id=81322 R8474_RS00235 WP_069288092.1 40668..41561(+) (comR) [Streptococcus pneumoniae strain PZ900700003]
ATGGATGAGTTGAAACGTGAAATTGGTTATAAAATCAAAACTATTAGGCGATCTTGTGGAAAAACTCAGATAGATATTTG
TGGTGATGAATCAGAGTTGACGATTCGTCAGCTAGCACGTATTGAAAATGGGCAAGCTTTAGCAACACTTCCTAAATTAT
TATTGATTGCGGATAAACTTGGAGTATCATTACAGAATATTGTGGATGTTAAGGTTATAGAGATTCCAAAAGGATTCCTA
AAACTCAAAGATGAGCTGATTCATTCTCAAACCTACGCTGATAAGGGAAGAATCGAACGAAAAGAAGCTATACTTGAGGA
AATATATGAAAACTATTATGAGAATTTGCCTGAGGAAGAGCAGTTAATTGTGGATGTGACACAAGCTCGTTTTGATATTT
ATGGTAGTTCAGATGTGACCTACGGTTTAGGGTTAGTGGAAGAATATTTCCAGCAGTTATTAAAAAAGAAATATTTTTCT
GTAAATGATTTGTTGATTATTGAATTGTATTTCTTTTGTTGTGCTATGGGATTAGAAGATAAAGAACATTTTGAGGAGTT
AGCTCAAAAAGTATTGCTATGTTCAGAATATGAAGATAAGGCTAGCCTAGTTCAAATGGAAAAAGTTCTTCTGATCCTAT
TTATCCAAATTCAGACAGAGGATAGTCTGATATATATTCAAACATTTGAGAAAATTATTGCTAAAACAAGACATGTTTTT
TACCGACCTCATCTATTTTTGCTAAAGGCAAAATATGCTTTATTTGTAGACAAGAATATTTTAGAGGCAGAAAGTTTCTA
TGAAAAGGCGATTTCTCTAGCAGAATTGCTAGACGATCAGGTATTAGTTCAGAGAATTTTAGCAGAAAAACAGATAGATT
TCCCAACAACCTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (76-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	36.667	100	0.37