Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HXS60_RS04350 Genome accession   NZ_AP023042
Coordinates   853512..855887 (-) Length   791 a.a.
NCBI ID   WP_176486698.1    Uniprot ID   -
Organism   Helicobacter suis strain NHP19-4004     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 848512..860887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HXS60_RS04325 (NHP194004_08650) - 848655..849575 (+) 921 WP_104683434.1 transaldolase -
  HXS60_RS04330 (NHP194004_08660) - 849567..850454 (-) 888 WP_176486697.1 aspartate carbamoyltransferase catalytic subunit -
  HXS60_RS04335 (NHP194004_08670) - 850485..850985 (+) 501 WP_006565381.1 hypothetical protein -
  HXS60_RS04340 (NHP194004_08680) nusA 851057..852181 (+) 1125 WP_034377202.1 transcription termination factor NusA -
  HXS60_RS04345 (NHP194004_08690) - 852187..853497 (-) 1311 WP_034377204.1 anaerobic C4-dicarboxylate transporter -
  HXS60_RS04350 (NHP194004_08700) comB4 853512..855887 (-) 2376 WP_176486698.1 FtsK/SpoIIIE domain-containing protein Machinery gene
  HXS60_RS04355 (NHP194004_08710) - 855979..856575 (-) 597 WP_006565383.1 outer membrane protein -
  HXS60_RS04360 - 856975..857178 (+) 204 WP_158656545.1 hypothetical protein -
  HXS60_RS04365 (NHP194004_08720) - 857479..857805 (-) 327 Protein_879 type II restriction endonuclease -
  HXS60_RS04370 (NHP194004_08730) - 857828..858727 (-) 900 WP_006565075.1 DNA adenine methylase -
  HXS60_RS04375 (NHP194004_08740) - 858759..859769 (-) 1011 WP_034375552.1 NADPH dehydrogenase -

Sequence

Protein


Download         Length: 791 a.a.        Molecular weight: 90559.02 Da        Isoelectric Point: 8.0923

>NTDB_id=80793 HXS60_RS04350 WP_176486698.1 853512..855887(-) (comB4) [Helicobacter suis strain NHP19-4004]
MFHVLWDFLYNKTLDLLVGALPKVHCMTEENNILGLYDARFLLTKSEQLVGMLQIEGLSANAMAKEELQGYFQSKQNALD
QLQGVVLRVHTKRRKLQLKHDHHLSNPYAQAILNQFENKTIYENTYTLIFETTKSPIKDFLEQKKLEITTSASKQLYEHQ
AKLLSDCMSKITHALQPFKPKPLTATQALNFYAEFINGFFMPLKPTLGFLEDSYIATNVHFKKDYYIQEYHESRVHNRIL
GIKAYASKTLSSLVFTNLLHQEKELDIIFSIEPLETQKALSFIQEKIRLTISSLVKQELQEYYERIQAKQLCLQKIACNL
ILRHPHLETLNQETQEVLSLLSNGHLVGVVETLGLRPAYFSFFPGRLHLNPRLRCQSSQALACLLVFEKPNRGFKSNSWG
NMPLSVFKNLDHSPYLFNFHNQEVPHNTAQHSLHRANGHTMIIGATGTGKTTLMSFLMMSALKYDRLNILALDRAYGLFS
YTHYFSGTYNSGTHFKINPLSLKNSKENIDFLHSFYAAMLNIPLKPQNQLDIQASNAISNTLKTLYATLPPQSFSLQDFK
DAFIHTQALNLEPYLHNPLFNALEDSLEFKTPITTINMDAISTNPKDLGLLAYYIFYKILHQALEYNRGFLLFIDEFKSY
AQNSILNTHINTLITQARKANGVVVLALQDTNQLNSIQDAASFIKNMGTLIFYPQKHIDSTALSRDFGIKLSHMEQHFLE
NTPMHAHQILVKNMGDGSSSIIDVNLQSLGPYLHIFNSNAGLAKHLQGLMQSYPETWREVFLQSQDWEFAI

Nucleotide


Download         Length: 2376 bp        

>NTDB_id=80793 HXS60_RS04350 WP_176486698.1 853512..855887(-) (comB4) [Helicobacter suis strain NHP19-4004]
ATGTTCCATGTGCTGTGGGATTTTTTATACAATAAAACCCTAGATTTATTAGTAGGTGCTTTGCCAAAAGTACATTGCAT
GACTGAGGAAAATAATATTCTAGGGCTATATGATGCGCGCTTTTTACTCACTAAGAGCGAACAGTTAGTAGGAATGCTAC
AAATTGAGGGCTTGAGTGCAAATGCGATGGCCAAAGAGGAGCTACAAGGGTATTTTCAAAGTAAGCAAAATGCTTTAGAT
CAGTTGCAAGGGGTTGTTTTGCGCGTACACACTAAACGCCGTAAATTACAACTCAAACATGACCACCATTTGAGTAACCC
TTATGCCCAAGCCATCCTTAATCAATTTGAAAACAAAACTATTTATGAAAACACCTACACTCTTATTTTTGAAACCACTA
AAAGCCCTATTAAAGATTTTTTAGAACAAAAGAAGCTAGAGATCACTACAAGTGCCTCCAAACAGCTGTATGAACACCAA
GCTAAACTGCTCTCTGATTGCATGTCTAAAATAACCCATGCACTCCAGCCCTTTAAACCAAAACCCCTCACCGCCACGCA
AGCCCTAAATTTCTACGCAGAATTTATCAACGGCTTTTTTATGCCTCTTAAGCCTACTTTGGGTTTTTTAGAAGATAGTT
ACATTGCGACTAATGTACATTTTAAAAAAGATTATTATATTCAAGAATATCATGAATCGCGCGTGCATAACCGCATTTTG
GGGATTAAGGCCTATGCTAGTAAAACTCTAAGCTCTTTAGTCTTTACAAACTTATTACACCAAGAAAAAGAATTAGACAT
TATTTTTTCTATAGAGCCTTTAGAGACGCAAAAAGCCCTGTCCTTTATCCAAGAAAAAATCCGTTTGACCATTAGCTCAC
TAGTCAAGCAAGAGTTACAAGAATATTATGAGCGTATCCAAGCCAAACAGCTTTGTTTACAAAAAATTGCCTGTAATCTT
ATTCTTAGACACCCCCATTTAGAAACACTCAACCAAGAAACCCAAGAGGTTTTAAGCCTTTTATCTAATGGACATCTAGT
AGGCGTTGTAGAAACCTTAGGACTTAGACCCGCTTATTTTTCCTTCTTTCCCGGGCGTTTGCATTTAAACCCTCGTTTGC
GTTGCCAAAGTTCTCAAGCCCTAGCTTGTTTACTCGTCTTTGAAAAGCCAAATCGTGGTTTTAAATCAAACTCTTGGGGA
AACATGCCCCTTAGTGTGTTTAAAAACCTCGATCATTCGCCCTATCTTTTTAATTTCCATAACCAAGAAGTACCACACAA
TACAGCACAACATAGTTTACATAGGGCTAATGGGCATACCATGATTATTGGCGCTACAGGGACGGGTAAGACGACTTTAA
TGAGTTTTTTAATGATGAGTGCGCTTAAATACGATCGGCTTAATATTCTAGCTTTAGATCGCGCTTATGGGTTGTTTTCC
TACACCCATTATTTTAGCGGCACTTACAACTCAGGTACGCATTTTAAAATCAACCCCCTATCTCTTAAAAACTCCAAAGA
AAATATAGATTTTTTACACTCTTTTTATGCGGCTATGCTAAATATCCCCCTAAAGCCACAAAACCAGCTAGATATTCAAG
CCAGTAACGCCATTTCTAACACCCTTAAAACTTTATACGCTACCTTGCCCCCTCAAAGTTTTTCTTTGCAAGATTTTAAA
GACGCATTCATTCATACCCAAGCTTTAAATTTAGAACCCTATTTACATAACCCGCTTTTTAACGCCTTAGAAGATAGCCT
AGAATTTAAAACGCCTATCACAACTATTAACATGGACGCTATTAGTACTAATCCTAAAGATTTAGGGCTTTTGGCTTACT
ATATTTTCTATAAGATTTTACACCAAGCCCTAGAATACAACCGCGGCTTTTTACTCTTTATAGATGAATTTAAAAGTTAT
GCGCAAAATTCTATCCTAAACACACATATTAACACTTTAATCACCCAAGCTAGAAAGGCTAATGGGGTGGTGGTTTTGGC
CTTGCAAGATACAAACCAACTTAACTCTATCCAAGATGCGGCTAGTTTTATTAAAAACATGGGTACTTTGATCTTTTATC
CACAAAAACACATTGATAGTACAGCCCTTAGCCGTGATTTTGGAATCAAACTTAGCCACATGGAACAACACTTTTTAGAA
AACACCCCCATGCATGCCCACCAAATTCTAGTTAAAAACATGGGCGATGGTAGTTCTAGTATTATTGATGTTAATTTACA
ATCTCTAGGCCCTTATTTACATATTTTTAATTCCAATGCAGGCTTAGCCAAACATTTACAGGGTCTAATGCAAAGCTATC
CTGAGACTTGGCGAGAGGTGTTTTTGCAATCTCAAGATTGGGAGTTTGCAATTTAA

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(397-464)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(178-372)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

51.389

100

0.515

Multiple sequence alignment