Detailed information
Bioinformatically predicted
Overview
| Name | comB2 | Type | Machinery gene |
| Locus tag | HXS60_RS02190 | Genome accession | NZ_AP023042 |
| Coordinates | 432835..433119 (+) | Length | 94 a.a. |
| NCBI ID | WP_006563999.1 | Uniprot ID | - |
| Organism | Helicobacter suis strain NHP19-4004 | ||
| Function | transformation-associated type IV transport system (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 432359..469299 | 432835..433119 | within | 0 |
Gene organization within MGE regions
Location: 432359..469299
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HXS60_RS02185 (NHP194004_04430) | - | 432359..432838 (+) | 480 | WP_034375662.1 | hypothetical protein | - |
| HXS60_RS02190 (NHP194004_04440) | comB2 | 432835..433119 (+) | 285 | WP_006563999.1 | TrbC/VirB2 family protein | Machinery gene |
| HXS60_RS02195 (NHP194004_04450) | comB3 | 433130..433393 (+) | 264 | WP_176486646.1 | competence protein ComB | Machinery gene |
| HXS60_RS02200 (NHP194004_04460) | - | 433404..433640 (+) | 237 | WP_034375660.1 | hypothetical protein | - |
| HXS60_RS02205 (NHP194004_04470) | - | 433640..436216 (+) | 2577 | WP_176486647.1 | VirB4 family type IV secretion/conjugal transfer ATPase | - |
| HXS60_RS02210 | - | 436218..436352 (+) | 135 | WP_000738747.1 | hypothetical protein | - |
| HXS60_RS02215 (NHP194004_04480) | - | 436380..437645 (-) | 1266 | WP_176486648.1 | RNA-guided endonuclease TnpB family protein | - |
| HXS60_RS02220 (NHP194004_04490) | tnpA | 437710..438138 (+) | 429 | WP_034376438.1 | IS200/IS605 family transposase | - |
| HXS60_RS09110 | - | 438129..438281 (-) | 153 | WP_232087249.1 | hypothetical protein | - |
| HXS60_RS02225 (NHP194004_04500) | - | 438217..438684 (+) | 468 | Protein_458 | hypothetical protein | - |
| HXS60_RS02230 (NHP194004_04510) | tnpA | 438737..439165 (-) | 429 | WP_034376438.1 | IS200/IS605 family transposase | - |
| HXS60_RS02235 (NHP194004_04520) | - | 439230..440495 (+) | 1266 | WP_176486648.1 | RNA-guided endonuclease TnpB family protein | - |
| HXS60_RS02240 (NHP194004_04530) | - | 440500..441144 (+) | 645 | Protein_461 | type IV secretion system protein | - |
| HXS60_RS02245 (NHP194004_04540) | - | 441141..442808 (+) | 1668 | WP_006565091.1 | TrbG/VirB9 family P-type conjugative transfer protein | - |
| HXS60_RS02250 (NHP194004_04550) | - | 442826..444091 (-) | 1266 | WP_176486648.1 | RNA-guided endonuclease TnpB family protein | - |
| HXS60_RS02255 (NHP194004_04560) | tnpA | 444156..444584 (+) | 429 | WP_034376438.1 | IS200/IS605 family transposase | - |
| HXS60_RS09115 (NHP194004_04570) | - | 444641..444865 (+) | 225 | WP_232087250.1 | hypothetical protein | - |
| HXS60_RS02265 (NHP194004_04580) | - | 444975..447035 (+) | 2061 | WP_034375651.1 | type IA DNA topoisomerase | - |
| HXS60_RS02270 (NHP194004_04590) | - | 447090..447560 (+) | 471 | WP_000965788.1 | hypothetical protein | - |
| HXS60_RS02275 (NHP194004_04600) | - | 447530..447685 (+) | 156 | WP_158650290.1 | hypothetical protein | - |
| HXS60_RS02280 (NHP194004_04610) | - | 447667..448272 (-) | 606 | WP_040499212.1 | hypothetical protein | - |
| HXS60_RS02285 (NHP194004_04620) | - | 448250..448618 (-) | 369 | WP_021305613.1 | hypothetical protein | - |
| HXS60_RS09120 | - | 448665..449332 (-) | 668 | Protein_471 | AAA family ATPase | - |
| HXS60_RS02300 (NHP194004_04650) | - | 449970..450134 (+) | 165 | WP_006564534.1 | hypothetical protein | - |
| HXS60_RS02305 (NHP194004_04660) | - | 450135..450779 (+) | 645 | Protein_473 | ArdC family protein | - |
| HXS60_RS02310 (NHP194004_04670) | tnpA | 450829..451257 (-) | 429 | WP_034376438.1 | IS200/IS605 family transposase | - |
| HXS60_RS02315 (NHP194004_04680) | - | 451322..452587 (+) | 1266 | WP_176486648.1 | RNA-guided endonuclease TnpB family protein | - |
| HXS60_RS02320 (NHP194004_04690) | - | 452592..453002 (+) | 411 | Protein_476 | hypothetical protein | - |
| HXS60_RS02325 (NHP194004_04700) | - | 453002..454858 (+) | 1857 | WP_176486650.1 | hypothetical protein | - |
| HXS60_RS02330 (NHP194004_04710) | - | 454953..456386 (+) | 1434 | WP_176485349.1 | hypothetical protein | - |
| HXS60_RS02335 (NHP194004_04720) | - | 456383..457624 (+) | 1242 | WP_176486651.1 | P-type conjugative transfer protein TrbL | - |
| HXS60_RS02340 | - | 457746..457913 (-) | 168 | WP_176486652.1 | hypothetical protein | - |
| HXS60_RS02345 (NHP194004_04730) | - | 457898..459163 (+) | 1266 | WP_034375704.1 | hypothetical protein | - |
| HXS60_RS02350 (NHP194004_04740) | - | 459168..460181 (-) | 1014 | WP_034375706.1 | hypothetical protein | - |
| HXS60_RS02355 | - | 460401..460855 (+) | 455 | Protein_483 | CAAX protease | - |
| HXS60_RS02360 (NHP194004_04770) | - | 460896..461147 (+) | 252 | WP_000006537.1 | hypothetical protein | - |
| HXS60_RS02365 (NHP194004_04780) | - | 461119..461922 (+) | 804 | WP_034375708.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| HXS60_RS02370 (NHP194004_04790) | - | 462239..463306 (-) | 1068 | WP_001120380.1 | tyrosine-type recombinase/integrase | - |
| HXS60_RS02375 (NHP194004_04800) | - | 464403..466388 (-) | 1986 | WP_176485362.1 | relaxase/mobilization nuclease domain-containing protein | - |
| HXS60_RS02380 (NHP194004_04810) | - | 467541..467708 (+) | 168 | Protein_488 | ATP phosphoribosyltransferase regulatory subunit | - |
| HXS60_RS02385 (NHP194004_04820) | - | 467673..468155 (-) | 483 | WP_309298907.1 | nitrate- and nitrite sensing domain-containing protein | - |
| HXS60_RS02390 (NHP194004_04830) | - | 468475..469299 (+) | 825 | WP_176486132.1 | site-specific integrase | - |
Sequence
Protein
Download Length: 94 a.a. Molecular weight: 10736.06 Da Isoelectric Point: 11.1589
>NTDB_id=80790 HXS60_RS02190 WP_006563999.1 432835..433119(+) (comB2) [Helicobacter suis strain NHP19-4004]
MKKLRHFRKLIAFLGFSPPLLQADMTTFFNSIEQQLTSPTAKGILMVIFLGLAIFIWKNLDRWKEILMTVLAIAIGAAIF
FKAPALANWFMSIF
MKKLRHFRKLIAFLGFSPPLLQADMTTFFNSIEQQLTSPTAKGILMVIFLGLAIFIWKNLDRWKEILMTVLAIAIGAAIF
FKAPALANWFMSIF
Nucleotide
Download Length: 285 bp
>NTDB_id=80790 HXS60_RS02190 WP_006563999.1 432835..433119(+) (comB2) [Helicobacter suis strain NHP19-4004]
ATGAAAAAATTAAGGCATTTTAGAAAGCTTATCGCCTTTTTAGGTTTTTCACCACCTTTATTACAAGCGGATATGACTAC
CTTTTTTAATAGCATTGAACAACAACTCACTAGCCCCACCGCTAAGGGTATTTTGATGGTCATTTTTTTAGGGCTTGCTA
TTTTCATATGGAAAAATTTAGACAGATGGAAAGAAATCTTAATGACAGTCCTTGCTATTGCCATAGGCGCTGCAATCTTT
TTTAAAGCCCCAGCCTTAGCTAATTGGTTTATGAGTATTTTTTAA
ATGAAAAAATTAAGGCATTTTAGAAAGCTTATCGCCTTTTTAGGTTTTTCACCACCTTTATTACAAGCGGATATGACTAC
CTTTTTTAATAGCATTGAACAACAACTCACTAGCCCCACCGCTAAGGGTATTTTGATGGTCATTTTTTTAGGGCTTGCTA
TTTTCATATGGAAAAATTTAGACAGATGGAAAGAAATCTTAATGACAGTCCTTGCTATTGCCATAGGCGCTGCAATCTTT
TTTAAAGCCCCAGCCTTAGCTAATTGGTTTATGAGTATTTTTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB2 | Helicobacter pylori 26695 |
57.778 |
95.745 |
0.553 |