Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HXS58_RS07165 Genome accession   NZ_AP023036
Coordinates   1387528..1389903 (+) Length   791 a.a.
NCBI ID   WP_006565382.1    Uniprot ID   -
Organism   Helicobacter suis strain NHP19-0020     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1382528..1394903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HXS58_RS07140 (NHP190020_14570) - 1383646..1384656 (+) 1011 WP_034375552.1 NADPH dehydrogenase -
  HXS58_RS07145 (NHP190020_14580) - 1384688..1385587 (+) 900 WP_006565075.1 DNA adenine methylase -
  HXS58_RS07150 (NHP190020_14590) - 1385610..1385936 (+) 327 Protein_1420 type II restriction endonuclease -
  HXS58_RS07155 - 1386237..1386440 (-) 204 WP_158656195.1 hypothetical protein -
  HXS58_RS07160 (NHP190020_14600) - 1386840..1387436 (+) 597 WP_373867759.1 outer membrane protein -
  HXS58_RS07165 (NHP190020_14610) comB4 1387528..1389903 (+) 2376 WP_006565382.1 FtsK/SpoIIIE domain-containing protein Machinery gene
  HXS58_RS07170 (NHP190020_14620) - 1389918..1391226 (+) 1309 Protein_1424 anaerobic C4-dicarboxylate transporter -
  HXS58_RS07175 (NHP190020_14630) nusA 1391232..1392356 (-) 1125 WP_034377202.1 transcription termination factor NusA -
  HXS58_RS07180 (NHP190020_14640) - 1392428..1392928 (-) 501 WP_006565381.1 hypothetical protein -
  HXS58_RS07185 (NHP190020_14650) - 1392959..1393846 (+) 888 WP_006565380.1 aspartate carbamoyltransferase catalytic subunit -
  HXS58_RS07190 (NHP190020_14660) - 1393838..1394758 (-) 921 WP_104683434.1 transaldolase -

Sequence

Protein


Download         Length: 791 a.a.        Molecular weight: 90575.02 Da        Isoelectric Point: 8.0923

>NTDB_id=80760 HXS58_RS07165 WP_006565382.1 1387528..1389903(+) (comB4) [Helicobacter suis strain NHP19-0020]
MFHVLWDFLYNKTLDLLVGALPKVHCMTEENNILGLYDARFLLTKSEQLVGMLQIEGLSANAMAKEELQGYFQSKQNALD
QLQGVVLRVHTKRRKLQLKHDHHLSNPYAQSILNQFENKTIYENTYTLIFETTKSPIKDFLEQKKLEITTSASKQLYEHQ
AKLLSDCMSKITHALQPFKPKPLTATQALNFYAEFINGFFMPLKPTLGFLEDSYIATNVHFKKDYYIQEYHESRVHNRIL
GIKAYASKTLSSLVFTNLLHQEKELDIIFSIEPLETQKALSFIQEKIRLTISSLVKQELQEYYERIQAKQLCLQKIACNL
ILRHPHLETLNQETQEVLSLLSNGHLVGVVETLGLRPAYFSFFPGRLHLNPRLRCQSSQALACLLVFEKPNRGFKSNSWG
NMPLSVFKNLDHSPYLFNFHNQEVPHNTAQHSLHRANGHTMIIGATGTGKTTLMSFLMMSALKYDRLNILALDRAYGLFS
YTHYFSGTYNSGTHFKINPLSLKNSKENIDFLHSFYAAMLNIPLKPQNQLDIQASNAISNTLKTLYATLPPQSFSLQDFK
DAFIHTQALNLEPYLHNPLFNALEDSLEFKTPITTINMDAISTNPKDLGLLAYYIFYKILHQALEYNRGFLLFIDEFKSY
AQNSILNTHINTLITQARKANGVVVLALQDTNQLNSIQDAASFIKNMGTLIFYPQKHIDSTALSRDFGIKLSHMEQHFLE
NTPMHAHQILVKNMGDGSSSIIDVNLQSLGPYLHIFNSNAGLAKHLQGLMQSYPETWREVFLQSQDWEFAI

Nucleotide


Download         Length: 2376 bp        

>NTDB_id=80760 HXS58_RS07165 WP_006565382.1 1387528..1389903(+) (comB4) [Helicobacter suis strain NHP19-0020]
ATGTTCCATGTGCTGTGGGATTTTTTATACAATAAAACCCTAGATTTATTAGTAGGTGCTTTGCCAAAAGTACATTGCAT
GACTGAGGAAAATAATATTCTAGGGCTATATGATGCGCGCTTTTTACTCACTAAGAGCGAACAGTTAGTAGGAATGCTAC
AAATTGAGGGCTTGAGTGCAAATGCGATGGCCAAAGAGGAGCTACAAGGGTATTTTCAAAGTAAGCAAAATGCTTTAGAT
CAGTTGCAAGGGGTTGTTTTGCGCGTACACACTAAACGCCGTAAATTACAACTCAAACATGACCACCATTTGAGTAACCC
TTATGCCCAATCCATCCTTAATCAATTTGAAAACAAAACTATTTATGAAAACACCTACACTCTTATTTTTGAAACCACTA
AAAGCCCTATTAAAGATTTTTTAGAACAAAAGAAGCTAGAGATCACTACAAGTGCCTCCAAACAGCTGTATGAACACCAA
GCTAAACTGCTCTCTGATTGCATGTCTAAAATAACCCATGCACTCCAGCCCTTTAAACCAAAACCCCTCACCGCCACGCA
AGCCCTAAATTTCTACGCAGAATTTATCAACGGCTTTTTTATGCCTCTTAAGCCTACTTTGGGTTTTTTAGAAGATAGTT
ACATTGCGACTAATGTACATTTTAAAAAAGATTATTATATTCAAGAATATCATGAATCGCGCGTGCATAACCGCATTTTG
GGGATTAAGGCCTATGCTAGTAAAACTCTAAGCTCTTTAGTCTTTACAAACTTATTACACCAAGAAAAAGAATTAGACAT
TATTTTTTCTATAGAGCCTTTAGAGACGCAAAAAGCCCTGTCCTTTATCCAAGAAAAAATCCGTTTGACCATTAGCTCAC
TAGTCAAGCAAGAGTTACAAGAATATTATGAGCGTATCCAAGCCAAACAGCTTTGTTTACAAAAAATTGCCTGTAATCTT
ATTCTTAGACACCCCCATTTAGAAACACTCAACCAAGAAACCCAAGAGGTTTTAAGCCTTTTATCTAATGGACATCTAGT
AGGCGTTGTAGAAACCTTAGGACTTAGACCCGCTTATTTTTCCTTCTTTCCCGGGCGTTTGCATTTAAACCCTCGTTTGC
GTTGCCAAAGTTCTCAAGCCCTAGCTTGTTTACTCGTCTTTGAAAAGCCAAATCGTGGTTTTAAATCAAACTCTTGGGGA
AACATGCCCCTTAGTGTGTTTAAAAACCTCGATCATTCGCCCTATCTTTTTAATTTCCATAACCAAGAAGTACCACACAA
TACAGCACAACATAGTTTACATAGGGCTAATGGGCATACCATGATTATTGGCGCTACAGGGACGGGTAAGACGACTTTAA
TGAGTTTTTTAATGATGAGTGCGCTTAAATACGATCGGCTTAATATTCTAGCTTTAGATCGCGCTTATGGGTTGTTTTCC
TACACCCATTATTTTAGCGGCACTTACAACTCAGGTACGCATTTTAAAATCAACCCCCTATCTCTTAAAAACTCCAAAGA
AAATATAGATTTTTTACACTCTTTTTATGCGGCTATGCTAAATATCCCCCTAAAGCCACAAAACCAGCTAGATATTCAAG
CCAGTAACGCCATTTCTAACACCCTTAAAACTTTATACGCTACCTTGCCCCCTCAAAGTTTTTCTTTGCAAGATTTTAAA
GACGCATTCATTCATACCCAAGCTTTAAATTTAGAACCCTATTTACATAACCCGCTTTTTAACGCCTTAGAAGATAGCCT
AGAATTTAAAACGCCTATCACAACTATTAACATGGACGCTATTAGTACTAATCCTAAAGATTTAGGGCTTTTGGCTTACT
ATATTTTCTATAAGATTTTACACCAAGCCCTAGAATACAACCGCGGCTTTTTACTCTTTATAGATGAATTTAAAAGTTAT
GCGCAAAACTCTATTTTAAACACACATATCAATACCCTAATCACCCAAGCCAGAAAGGCTAATGGCGTGGTGGTTTTGGC
CTTGCAAGATACAAACCAGTTAAACTCTATCCAAGATGCGGCCAGTTTTATTAAAAACATGGGTACTTTGATCTTTTATC
CACAAAAGCACATTGATAGTACAGCCCTTAGCCGTGATTTTGGAATCAAACTTAGCCACATGGAACAACACTTTTTAGAA
AACACCCCCATGCATGCCCACCAAATTCTAGTTAAAAACATGGGCGATGGTAGTTCTAGTATTATTGATGTTAATTTACA
ATCTCTAGGCCCTTATTTACATATTTTTAATTCCAATGCAGGCTTAGCCAAACATTTACAGGGTCTAATGCAAAGCTATC
CTGAGACTTGGCGAGAGGTGTTTTTGCAATCTCAAGATTGGGAGTTTGCAATTTAA

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(397-464)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(178-372)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

51.263

100

0.513

Multiple sequence alignment