Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   RL452_RS05935 Genome accession   NZ_CP134620
Coordinates   1219255..1220028 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain Sa9     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1214255..1225028
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL452_RS05915 (RL452_05910) trmFO 1214597..1215904 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  RL452_RS05920 (RL452_05915) xerC 1216323..1217219 (+) 897 WP_338597474.1 tyrosine recombinase XerC -
  RL452_RS05925 (RL452_05920) hslV 1217216..1217761 (+) 546 WP_000072680.1 ATP-dependent protease subunit HslV -
  RL452_RS05930 (RL452_05925) hslU 1217827..1219230 (+) 1404 WP_045158023.1 ATP-dependent protease ATPase subunit HslU -
  RL452_RS05935 (RL452_05930) codY 1219255..1220028 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  RL452_RS05940 (RL452_05935) - 1220079..1220171 (+) 93 WP_031788481.1 hypothetical protein -
  RL452_RS05945 (RL452_05940) rpsB 1220370..1221137 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  RL452_RS05950 (RL452_05945) - 1221171..1221284 (+) 114 WP_001789890.1 hypothetical protein -
  RL452_RS05955 (RL452_05950) tsf 1221319..1222200 (+) 882 WP_045158025.1 translation elongation factor Ts -
  RL452_RS05960 (RL452_05955) pyrH 1222337..1223059 (+) 723 WP_000057330.1 UMP kinase -
  RL452_RS05965 (RL452_05960) frr 1223078..1223632 (+) 555 WP_001280006.1 ribosome recycling factor -
  RL452_RS05970 (RL452_05965) - 1224005..1224775 (+) 771 WP_045158027.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=807130 RL452_RS05935 WP_000055337.1 1219255..1220028(+) (codY) [Staphylococcus aureus strain Sa9]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=807130 RL452_RS05935 WP_000055337.1 1219255..1220028(+) (codY) [Staphylococcus aureus strain Sa9]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCGATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
AGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTTATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428