Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   RL452_RS05375 Genome accession   NZ_CP134620
Coordinates   1100948..1103296 (+) Length   782 a.a.
NCBI ID   WP_001249278.1    Uniprot ID   Q2YXD1
Organism   Staphylococcus aureus strain Sa9     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1095948..1108296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL452_RS05355 (RL452_05350) rnhC 1097052..1097990 (-) 939 WP_001284268.1 ribonuclease HIII -
  RL452_RS05360 (RL452_05355) zapA 1098365..1098624 (+) 260 Protein_1042 cell division protein ZapA -
  RL452_RS05365 (RL452_05360) - 1098632..1099153 (+) 522 WP_000234076.1 CvpA family protein -
  RL452_RS05370 (RL452_05365) polX 1099226..1100938 (+) 1713 WP_000161929.1 DNA polymerase/3'-5' exonuclease PolX -
  RL452_RS05375 (RL452_05370) mutS/mutS2 1100948..1103296 (+) 2349 WP_001249278.1 endonuclease MutS2 Machinery gene
  RL452_RS05380 (RL452_05375) trxA 1103469..1103783 (+) 315 WP_001018928.1 thioredoxin -
  RL452_RS05385 (RL452_05380) - 1103846..1103941 (-) 96 WP_031844936.1 hypothetical protein -
  RL452_RS05390 (RL452_05385) uvrC 1104107..1105888 (+) 1782 WP_000390530.1 excinuclease ABC subunit UvrC Machinery gene
  RL452_RS05395 (RL452_05390) - 1106212..1106826 (+) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -

Sequence

Protein


Download         Length: 782 a.a.        Molecular weight: 88638.26 Da        Isoelectric Point: 6.2034

>NTDB_id=807124 RL452_RS05375 WP_001249278.1 1100948..1103296(+) (mutS/mutS2) [Staphylococcus aureus strain Sa9]
MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADI
GGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRS
KISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISR
LRHDEAIEKERILTQLTGYVAADKDALLVAEHVMGQLDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVA
NTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIIMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNI
VEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSCNREGVMNASVEFDVDTLSPTY
KLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQ
QFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIV
AGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIE
LDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK

Nucleotide


Download         Length: 2349 bp        

>NTDB_id=807124 RL452_RS05375 WP_001249278.1 1100948..1103296(+) (mutS/mutS2) [Staphylococcus aureus strain Sa9]
ATGAGACAAAAAACATTAGACGTCTTAGAATTTGAAAAAATAAAATCACTCGTTGCCAATGAAACTATTAGTGACTTAGG
CTTGGAAAAGGTCAATCAAATGATGCCAGCTACTAATTTTGAAACGGTTGTTTTTCAAATGGAAGAAACGGATGAGATTG
CTCAAATCTATAATAAGCATCGTTTACCAAGCTTGAGTGGCTTATCTAAAGTATCAGCATTCATTCATCGCGCTGATATT
GGCGGCGTTTTAAATGTATCAGAGCTTAACTTGATAAAAAGATTAATTCAAGTACAAAATCAATTTAAGACATTTTATAA
TCAATTGGTTGAAGAAGATGAAGGTGTTAAATATCCAATATTAGATGACAAGATGAATCAATTACCTGTGTTAACCGATC
TTTTTCAACAAATAAATGAAACATGTGATACGTACGATTTATATGATAATGCGAGTTATGAATTGCAAGGGATTAGAAGT
AAAATTTCTAGCACGAATCAACGTATTAGACAAAATTTGGACCGTATTGTTAAAAGCCAAGCAAATCAGAAAAAATTATC
AGATGCTATTGTAACAGTTAGGAATGAAAGAAACGTTATACCTGTCAAAGCTGAATATCGACAAGATTTTAATGGGATTG
TACATGATCAATCTGCTTCAGGACAAACATTGTATATTGAGCCATCATCAGTTGTTGAAATGAATAATCAAATTAGTCGA
TTACGTCATGATGAAGCAATTGAAAAAGAACGCATTTTAACGCAACTAACTGGTTATGTGGCTGCGGACAAAGATGCACT
ACTTGTGGCAGAACATGTCATGGGTCAGTTAGATTTTTTAATCGCAAAAGCGAGATATAGTAGAAGTATTAAAGGAACAA
AGCCGATATTTAAAGAGGAACGTACTGTATATTTACCTAAAGCATACCATCCATTATTAAATCGTGAGACTGTTGTAGCT
AATACCATCGAATTTATGGAAGATATTGAAACGGTAATTATTACAGGACCGAATACAGGTGGTAAAACAGTAACATTAAA
AACATTAGGTTTAATTATTATTATGGCTCAATCAGGATTGTTGATTCCAACACTTGATGGTAGTCAGTTAAGTGTATTTA
AAAATGTATATTGCGATATCGGAGATGAACAATCAATAGAACAATCATTATCAACTTTTTCATCTCATATGACGAATATA
GTTGAGATTTTAAAGCATGCAGACAAACATAGTTTAGTTTTATTTGATGAATTAGGTGCAGGTACAGATCCAAGTGAAGG
TGCTGCCTTAGCAATGAGCATTTTAGATCATGTTAGAAAAATTGGTTCTCTAGTAATGGCAACGACGCACTATCCTGAAC
TTAAAGCATATAGTTGTAATCGAGAAGGCGTTATGAATGCGAGTGTAGAATTTGATGTAGATACTTTGAGTCCAACGTAT
AAGTTATTAATGGGTGTGCCGGGTCGTTCAAATGCTTTTGACATTTCTAAAAAGTTAGGTCTTAGTTTGAATATTATTAA
TAAGGCTAAGACGATGATTGGTACTGATGAAAAAGAAATAAATGAAATGATTGAATCATTAGAGCGTAATTACAAACGTG
TAGAGACACAGAGGTTAGAACTGGACCGTCTTGTAAAAGAAGCGGAGCAAGTGCATGATGATTTATCTAAGCAGTATCAA
CAATTCCAAAATTATGAAAAGTCTCTAATAGAGGAAGCGAAAGAAAAAGCAAATCAAAAGATTAAAGCTGCAACAAAAGA
AGCTGACGATATTATTAAAGATTTAAGACAATTGCGTGAACAAAAAGGTGCAGATGTTAAAGAACATGAATTGATTGATA
AAAAGAAACGATTAGATGATCATTATGAAGCGAAATCTATAAAGCAAAATGTACAAAAGCAAAAATACGATAAAATTGTT
GCTGGTGATGAAGTAAAAGTATTATCTTACGGTCAAAAGGGTGAAGTTTTAGAAATTGTCAATGATGAAGAAGCAATTGT
TCAAATGGGAATTATTAAAATGAAGTTACCTATTGAAGATTTAGAGAAAAAACAAAAAGAAAAAGTTAAGCCAACGAAAA
TGGTTACACGTCAAAATCGTCAAACAATTAAAACTGAACTTGACTTACGAGGCTACCGTTATGAGGATGCTTTAATTGAA
CTAGATCAATATTTAGATCAAGCCGTTTTAAGTAATTACGAACAAGTTTATATCATTCATGGTAAAGGTACAGGTGCACT
TCAAAAAGGTGTACAACAACATTTGAAAAAGCATAAAAGTGTTAGTGACTTTAGAGGTGGTATGCCAAGCGAAGGTGGAT
TTGGCGTTACCGTTGCAACACTAAAATAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(332-512)

MutS2 and Smr-associated SH3 domain (MSSS)

(641-681)

Smr domain (Smr)

(707-782)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2YXD1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

49.683

100

0.501