Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   RL453_RS01945 Genome accession   NZ_CP134618
Coordinates   429221..431569 (-) Length   782 a.a.
NCBI ID   WP_001249273.1    Uniprot ID   Q8NX56
Organism   Staphylococcus aureus strain IPLA15     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 424221..436569
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RL453_RS01925 (RL453_01920) - 425691..426305 (-) 615 WP_000079317.1 succinate dehydrogenase cytochrome b558 subunit -
  RL453_RS01930 (RL453_01925) uvrC 426629..428410 (-) 1782 WP_000390525.1 excinuclease ABC subunit UvrC Machinery gene
  RL453_RS01935 (RL453_01930) - 428576..428671 (+) 96 WP_001788625.1 hypothetical protein -
  RL453_RS01940 (RL453_01935) trxA 428734..429048 (-) 315 WP_001018928.1 thioredoxin -
  RL453_RS01945 (RL453_01940) mutS/mutS2 429221..431569 (-) 2349 WP_001249273.1 endonuclease MutS2 Machinery gene
  RL453_RS01950 (RL453_01945) polX 431579..433291 (-) 1713 WP_000161942.1 DNA polymerase/3'-5' exonuclease PolX -
  RL453_RS01955 (RL453_01950) - 433364..433885 (-) 522 WP_000234074.1 CvpA family protein -
  RL453_RS01960 (RL453_01955) zapA 433893..434152 (-) 260 Protein_390 cell division protein ZapA -
  RL453_RS01965 (RL453_01960) rnhC 434522..435460 (+) 939 WP_001284280.1 ribonuclease HIII -

Sequence

Protein


Download         Length: 782 a.a.        Molecular weight: 88656.22 Da        Isoelectric Point: 6.2036

>NTDB_id=807025 RL453_RS01945 WP_001249273.1 429221..431569(-) (mutS/mutS2) [Staphylococcus aureus strain IPLA15]
MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADI
GGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFHQINETCDTYDLYDNASYELQGIRS
KISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISR
LRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSVKGTKPIFKEDRTVYLPKAYHPLLNRETVVA
NTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNI
VEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTY
KLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQ
QFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIV
AGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIE
LDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK

Nucleotide


Download         Length: 2349 bp        

>NTDB_id=807025 RL453_RS01945 WP_001249273.1 429221..431569(-) (mutS/mutS2) [Staphylococcus aureus strain IPLA15]
ATGAGACAAAAAACATTAGACGTCTTAGAATTTGAAAAAATAAAATCACTCGTTGCCAATGAAACTATTAGTGACTTAGG
CTTGGAAAAGGTCAATCAAATGATGCCAGCTACTAATTTTGAAACGGTTGTTTTTCAAATGGAAGAAACGGATGAGATTG
CTCAAATTTATAATAAGCATCGTTTACCAAGCTTGAGTGGCTTATCTAAAGTATCAGCATTCATTCATCGCGCTGATATT
GGCGGCGTTTTAAATGTATCAGAGCTTAACTTGATAAAAAGATTAATTCAAGTACAAAATCAATTCAAGACATTTTATAA
TCAATTGGTTGAAGAAGATGAAGGTGTTAAATACCCAATATTAGATGACAAGATGAATCAATTACCTGTGTTAACTGATC
TTTTTCATCAAATAAATGAAACATGCGATACGTATGATTTATATGATAATGCGAGTTATGAATTGCAAGGGATTAGAAGT
AAAATTTCTAGCACGAATCAACGTATTAGACAAAATTTGGACCGTATTGTTAAAAGCCAAGCAAATCAGAAAAAATTATC
AGATGCTATTGTAACAGTTAGGAATGAAAGAAACGTTATACCTGTCAAAGCTGAATATCGACAAGATTTTAATGGGATTG
TACATGATCAATCTGCTTCAGGACAAACATTGTATATTGAGCCATCATCAGTTGTTGAAATGAATAATCAAATTAGTCGA
TTACGTCATGACGAAGCAATTGAAAAAGAACGCATTTTAACGCAACTAACTGGTTATGTGGCTGCGGACAAAGATGCACT
ACTTGTGGCAGAACAAGTCATGGGTCAGTTAGATTTTTTAATCGCAAAAGCGAGATATAGTAGAAGTGTTAAAGGAACAA
AGCCGATATTTAAAGAGGACCGTACTGTATATTTACCTAAAGCATACCATCCATTATTAAATCGTGAGACTGTTGTAGCT
AATACCATCGAATTTATGGAAGATATTGAAACGGTAATTATTACAGGACCGAATACAGGTGGTAAAACTGTAACATTAAA
AACATTAGGTTTAATTATTGTTATGGCTCAATCAGGATTGTTGATTCCCACACTTGATGGTAGTCAGTTAAGTGTATTTA
AAAATGTATATTGCGATATCGGAGATGAACAATCAATAGAACAATCATTATCAACTTTTTCATCTCATATGACGAATATA
GTTGAAATTTTAAAGCATGCAGACAAACATAGTTTAGTTTTATTTGATGAATTAGGTGCAGGTACAGATCCGAGTGAAGG
TGCTGCATTAGCAATGAGCATTTTAGATCATGTTAGAAAAATTGGTTCTCTAGTAATGGCAACGACGCACTATCCTGAAC
TTAAAGCATATAGTTATAATCGAGAAGGCGTTATGAATGCGAGTGTAGAATTTGATGTAGATACTTTGAGTCCAACGTAT
AAGTTATTAATGGGTGTGCCGGGTCGTTCAAATGCTTTTGACATTTCTAAAAAGTTAGGTCTTAGTTTGAATATTATTAA
TAAGGCTAAGACGATGATTGGTACTGATGAAAAAGAAATAAATGAAATGATTGAATCATTAGAGCGTAATTACAAACGTG
TAGAGACACAGAGGTTAGAACTGGACCGTCTTGTAAAAGAAGCGGAGCAAGTGCATGATGATTTATCTAAGCAGTATCAA
CAATTCCAAAATTATGAAAAGTCTCTAATAGAGGAAGCGAAAGAAAAAGCAAATCAGAAGATTAAGGCTGCAACAAAAGA
AGCTGACGATATTATTAAAGACTTAAGACAATTGCGTGAACAAAAAGGTGCAGATGTTAAAGAACATGAATTGATTGATA
AGAAGAAACGATTAGATGATCATTATGAAGCGAAATCTATAAAGCAAAATGTACAAAAGCAAAAATACGATAAAATTGTT
GCTGGTGATGAAGTAAAAGTATTATCTTACGGTCAAAAGGGTGAAGTTTTAGAAATTGTCAATGATGAAGAAGCAATTGT
TCAAATGGGAATTATTAAAATGAAGTTACCTATTGAAGATTTAGAGAAAAAACAAAAAGAAAAAGTTAAGCCAACGAAAA
TGGTTACACGTCAAAATCGTCAAACAATTAAAACTGAACTTGACTTACGAGGCTATCGTTATGAGGATGCTTTAATTGAA
CTAGATCAATATTTAGATCAAGCCGTTTTAAGTAATTACGAACAAGTTTATATCATTCATGGTAAAGGTACAGGTGCACT
TCAAAAAGGTGTACAACAACATTTGAAAAAGCATAAAAGTGTTAGTGACTTTAGAGGTGGTATGCCAAGCGAAGGTGGAT
TTGGCGTTACCGTTGCAACACTAAAATAA

Domains

Predicted by InterProScan.

Smr domain (Smr)

(707-782)

MutS2 and Smr-associated SH3 domain (MSSS)

(641-681)

MutS domain V (MutS_V)

(332-512)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8NX56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

50.063

100

0.505