Detailed information NTG0805156

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: P2T63_RS07955
• Genome accession: NZ_CP120352
• Coordinates: 1585555..1586391 (-)
• Length: 278 a.a.
• NCBI ID: WP_004049325.1
• Uniprot ID: A0A4V1PRC4
• Organism: Ligilactobacillus murinus strain PG1-1-10
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1580555..1591391

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P2T63_RS07925 (P2T63_07925)	-	1580696..1581301 (-)	606	WP_004049315.1	response regulator transcription factor	-
P2T63_RS07930 (P2T63_07930)	-	1581279..1582415 (-)	1137	WP_004049316.1	sensor histidine kinase	-
P2T63_RS07935 (P2T63_07935)	-	1582417..1583136 (-)	720	WP_004049317.1	ABC transporter permease	-
P2T63_RS07940 (P2T63_07940)	-	1583120..1584010 (-)	891	WP_004049319.1	ABC transporter ATP-binding protein	-
P2T63_RS07945 (P2T63_07945)	-	1584142..1585017 (-)	876	WP_004049321.1	CPBP family intramembrane glutamic endopeptidase	-
P2T63_RS07950 (P2T63_07950)	-	1585244..1585555 (-)	312	WP_004049323.1	hypothetical protein	-
P2T63_RS07955 (P2T63_07955)	endA	1585555..1586391 (-)	837	WP_004049325.1	DNA/RNA non-specific endonuclease	Machinery gene
P2T63_RS07960 (P2T63_07960)	asnA	1586451..1587458 (-)	1008	WP_004049328.1	aspartate--ammonia ligase	-
P2T63_RS07965 (P2T63_07965)	-	1587639..1588286 (+)	648	WP_004049330.1	nitroreductase	-
P2T63_RS07970 (P2T63_07970)	-	1588455..1588880 (-)	426	WP_004049332.1	N-acetyltransferase	-
P2T63_RS07975 (P2T63_07975)	-	1588948..1589334 (+)	387	WP_004049334.1	iron chaperone	-
P2T63_RS07980 (P2T63_07980)	-	1590106..1590372 (-)	267	WP_004049336.1	hypothetical protein	-
P2T63_RS07985 (P2T63_07985)	-	1590700..1590879 (-)	180	WP_039936126.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30334.02 Da
• Isoelectric Point: 10.5647

>NTDB_id=805156 P2T63_RS07955 WP_004049325.1 1585555..1586391(-) (endA) [Ligilactobacillus murinus strain PG1-1-10]
MKFKKILTGFVAALMLSGAIGAPVTAKATTHYGGWRTHQKNSSSGSGELKKSTPSQQLAQTVLTPDVVKQLGGEQNLKWN
NSGAFIVNNNKTGLKAKVSSAPYATNEVDSLKRPTVANALLNRTTRQYKNRHQTNNGSTKWKPQGFKQLTNLSGAYNHAY
DRGHLLGYALVGNIRGFDASESNPKNIATQTAWANEANAKYSTGQNYYESLVRKALDRNKTVRYRVTNVYSGNNLVPSGA
HLEAKASDGSLEYNVFIPNVQKGLKIDYATGHAIKENN

Nucleotide

• Length: 837 bp

>NTDB_id=805156 P2T63_RS07955 WP_004049325.1 1585555..1586391(-) (endA) [Ligilactobacillus murinus strain PG1-1-10]
ATGAAGTTCAAAAAAATATTGACCGGATTTGTGGCAGCTTTGATGCTCAGTGGTGCGATCGGGGCACCGGTAACAGCTAA
AGCAACGACGCACTATGGTGGTTGGCGCACACATCAAAAAAATAGTTCGAGTGGCTCTGGTGAATTAAAAAAGAGCACTC
CATCACAACAATTAGCCCAAACGGTTTTGACGCCGGATGTTGTTAAACAATTAGGCGGTGAGCAAAATCTCAAATGGAAC
AACAGTGGGGCTTTTATCGTTAATAACAACAAGACAGGTTTAAAAGCTAAGGTTTCTAGTGCTCCTTATGCAACAAATGA
AGTCGATAGCTTAAAACGTCCGACGGTAGCTAATGCCCTTTTGAATAGGACAACACGGCAATACAAGAATCGCCACCAAA
CTAATAATGGTTCGACTAAATGGAAACCACAGGGCTTTAAGCAACTCACTAACTTAAGTGGCGCCTACAACCATGCTTAT
GATCGCGGACACTTACTAGGGTATGCTTTAGTGGGAAATATTCGTGGTTTTGATGCTAGTGAGAGCAATCCCAAAAATAT
TGCGACTCAGACAGCTTGGGCTAATGAAGCTAATGCAAAATATTCAACAGGTCAAAACTATTACGAAAGTCTTGTTCGAA
AAGCCTTAGATCGTAATAAGACTGTCCGTTATCGTGTGACAAATGTCTATAGCGGTAATAATTTAGTACCATCAGGCGCT
CATTTAGAAGCTAAAGCAAGTGATGGTTCGTTAGAGTATAATGTTTTTATCCCTAATGTTCAAAAGGGATTAAAGATCGA
CTATGCTACTGGTCATGCGATAAAGGAGAACAACTGA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (82-250)

3D structure

• AlphaFold DB: A0A4V1PRC4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	65.471	80.216	0.525
endA	Streptococcus pneumoniae D39	65.471	80.216	0.525
endA	Streptococcus pneumoniae R6	65.471	80.216	0.525
endA	Streptococcus pneumoniae TIGR4	65.471	80.216	0.525