Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   P1J77_RS07225 Genome accession   NZ_CP119597
Coordinates   1492497..1493450 (-) Length   317 a.a.
NCBI ID   WP_136274080.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1039     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1487497..1498450
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1J77_RS07195 (P1J77_07195) - 1487716..1488033 (-) 318 WP_011285355.1 thioredoxin family protein -
  P1J77_RS07200 (P1J77_07200) - 1488030..1488314 (-) 285 WP_002992749.1 DUF4651 domain-containing protein -
  P1J77_RS07205 (P1J77_07205) pepA 1488779..1489846 (+) 1068 WP_136263717.1 glutamyl aminopeptidase -
  P1J77_RS07210 (P1J77_07210) proC 1489894..1490664 (+) 771 WP_136274084.1 pyrroline-5-carboxylate reductase -
  P1J77_RS07215 (P1J77_07215) - 1490747..1491055 (-) 309 WP_010921804.1 hypothetical protein -
  P1J77_RS07220 (P1J77_07220) - 1491242..1492438 (-) 1197 WP_023612537.1 acetate kinase -
  P1J77_RS07225 (P1J77_07225) comYH 1492497..1493450 (-) 954 WP_136274080.1 class I SAM-dependent methyltransferase Machinery gene
  P1J77_RS07230 (P1J77_07230) comGG 1493548..1493874 (-) 327 WP_136274078.1 competence type IV pilus minor pilin ComGG -
  P1J77_RS07235 (P1J77_07235) comYF 1493858..1494292 (-) 435 WP_023612536.1 competence type IV pilus minor pilin ComGF Machinery gene
  P1J77_RS07240 (P1J77_07240) comGE 1494285..1494569 (-) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  P1J77_RS07245 (P1J77_07245) comGD 1494526..1494954 (-) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  P1J77_RS07250 (P1J77_07250) comYC 1494929..1495255 (-) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  P1J77_RS07255 (P1J77_07255) comYB 1495257..1496291 (-) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  P1J77_RS07260 (P1J77_07260) comYA 1496227..1497165 (-) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  P1J77_RS07265 (P1J77_07265) - 1497258..1497623 (-) 366 WP_002986560.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36013.13 Da        Isoelectric Point: 4.7205

>NTDB_id=799968 P1J77_RS07225 WP_136274080.1 1492497..1493450(-) (comYH) [Streptococcus pyogenes strain 1039]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLVPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=799968 P1J77_RS07225 WP_136274080.1 1492497..1493450(-) (comYH) [Streptococcus pyogenes strain 1039]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAAATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGTACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACACTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-288)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

65.823

99.685

0.656
  comYH Streptococcus mutans UA140

65.506

99.685

0.653