Detailed information NTG0797096

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: RA106_RS07700
• Genome accession: NZ_CP132900
• Coordinates: 1490094..1490879 (-)
• Length: 261 a.a.
• NCBI ID: WP_002951720.1
• Uniprot ID: Q5M305
• Organism: Streptococcus thermophilus strain CICC 20372
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1485094..1495879

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RA106_RS07665 (RA106_07660)	gatC	1485159..1485461 (-)	303	WP_002884769.1	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	-
RA106_RS07670 (RA106_07665)	-	1485601..1485855 (-)	255	WP_024010053.1	glycosyl transferase	-
RA106_RS07675 (RA106_07670)	-	1485868..1486065 (-)	198	WP_014608644.1	glycosyltransferase	-
RA106_RS07680 (RA106_07675)	-	1486393..1487834 (-)	1442	Protein_1473	6-phospho-beta-glucosidase	-
RA106_RS07685 (RA106_07680)	msrA	1487987..1488496 (-)	510	WP_024703984.1	peptide-methionine (S)-S-oxide reductase MsrA	-
RA106_RS07690 (RA106_07685)	-	1488508..1489356 (-)	849	WP_024703985.1	MetQ/NlpA family ABC transporter substrate-binding protein	-
RA106_RS07695 (RA106_07690)	-	1489480..1490031 (-)	552	WP_002946999.1	cysteine hydrolase family protein	-
RA106_RS07700 (RA106_07695)	codY	1490094..1490879 (-)	786	WP_002951720.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
RA106_RS07705 (RA106_07700)	-	1491139..1492353 (-)	1215	WP_002951721.1	pyridoxal phosphate-dependent aminotransferase	-
RA106_RS07710 (RA106_07705)	-	1492708..1493160 (+)	453	WP_002946987.1	universal stress protein	-
RA106_RS07715 (RA106_07710)	-	1493340..1493911 (+)	572	Protein_1480	IS30 family transposase	-
RA106_RS07720 (RA106_07715)	-	1493983..1494156 (-)	174	WP_011681546.1	hypothetical protein	-
RA106_RS07725 (RA106_07720)	-	1494217..1494591 (-)	375	WP_011681547.1	membrane protein	-
RA106_RS07730 (RA106_07725)	pflA	1494803..1495603 (-)	801	WP_002946980.1	pyruvate formate-lyase-activating protein	-

Sequence

Protein

• Length: 261 a.a.
• Molecular weight: 28919.13 Da
• Isoelectric Point: 4.5802

>NTDB_id=797096 RA106_RS07700 WP_002951720.1 1490094..1490879(-) (codY) [Streptococcus thermophilus strain CICC 20372]
MANLLDKTRKITSILQRSVDSLEGDLPYNNMAAQLADIIDCNAAIVNGGGALLGFAMKYKTNNDRVEKFFKAKQLPEEYI
RGISRVYDTQENIGIDSDLTIFPVELKDDFPDGLTTIAPIYGGGMRLGSFIIWRNDHDFVDDDLILVEIASTVVGLQLLH
LQTENLEETIRKQTAINMAINTLSYSEIKAVSAILNELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLNEGIYDKLKEYE

Nucleotide

• Length: 786 bp

>NTDB_id=797096 RA106_RS07700 WP_002951720.1 1490094..1490879(-) (codY) [Streptococcus thermophilus strain CICC 20372]
ATGGCAAATTTGCTTGATAAAACACGTAAAATTACTTCTATCTTGCAACGCTCAGTAGATAGTTTGGAAGGAGATCTTCC
ATACAACAACATGGCTGCTCAGTTGGCAGATATTATTGATTGTAATGCTGCTATTGTAAATGGTGGAGGTGCTCTCCTTG
GTTTTGCTATGAAATACAAAACCAACAATGACCGTGTGGAAAAGTTTTTTAAAGCTAAACAACTTCCAGAGGAATACATA
CGTGGTATCAGCCGTGTTTATGATACTCAAGAAAATATCGGTATTGACAGTGACTTGACCATCTTCCCAGTGGAATTAAA
AGATGATTTCCCTGACGGTTTGACTACAATTGCACCAATCTATGGTGGTGGTATGCGTCTTGGTTCTTTCATTATTTGGC
GTAACGACCATGATTTTGTGGACGACGACCTTATCTTGGTTGAGATTGCATCTACAGTAGTTGGTTTGCAATTGTTGCAT
CTTCAAACAGAAAACTTGGAAGAAACGATTCGTAAACAAACAGCTATTAATATGGCTATTAATACCTTGTCTTACTCAGA
AATCAAGGCAGTTTCAGCTATCTTGAATGAGTTGGACGGTTTAGAAGGTCGTTTGACAGCCTCTGTTATCGCGGACCGTA
TCGGAATTACTCGTTCTGTTATTGTTAATGCTCTTCGTAAATTAGAATCAGCTGGTATTATTGAAAGTCGTTCGCTTGGT
ATGAAAGGCACTTACCTTAAAGTCCTTAACGAAGGTATCTACGACAAATTGAAAGAATACGAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (3-182)

• CodY helix-turn-helix domain (HTH_CodY) (201-261)

3D structure

• AlphaFold DB: Q5M305

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	64.591	98.467	0.636
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	94.636	0.502