Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   PW252_RS07605 Genome accession   NZ_CP118735
Coordinates   1567667..1568503 (-) Length   278 a.a.
NCBI ID   WP_248049063.1    Uniprot ID   A0AA96VLY2
Organism   Streptococcus iners strain 29887     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1562667..1573503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW252_RS07590 (PW252_07590) uidA 1563014..1564813 (-) 1800 WP_248049061.1 beta-glucuronidase -
  PW252_RS07595 (PW252_07595) - 1564829..1565857 (-) 1029 WP_172050476.1 PfkB family carbohydrate kinase -
  PW252_RS07600 (PW252_07600) - 1565920..1567473 (-) 1554 WP_105113932.1 MFS transporter -
  PW252_RS07605 (PW252_07605) endA 1567667..1568503 (-) 837 WP_248049063.1 DNA/RNA non-specific endonuclease Machinery gene
  PW252_RS07610 (PW252_07610) - 1568533..1568724 (-) 192 WP_105113934.1 DNA-directed RNA polymerase subunit beta -
  PW252_RS07615 (PW252_07615) murA 1568717..1570000 (-) 1284 WP_248049065.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  PW252_RS07620 (PW252_07620) - 1570024..1570248 (-) 225 WP_172050474.1 DUF1146 family protein -
  PW252_RS07625 (PW252_07625) - 1570316..1570732 (-) 417 WP_105113936.1 F0F1 ATP synthase subunit epsilon -
  PW252_RS07630 (PW252_07630) atpD 1570743..1572149 (-) 1407 WP_105113937.1 F0F1 ATP synthase subunit beta -
  PW252_RS07635 (PW252_07635) - 1572169..1573047 (-) 879 WP_024398204.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 278 a.a.        Molecular weight: 30062.33 Da        Isoelectric Point: 7.5543

>NTDB_id=794742 PW252_RS07605 WP_248049063.1 1567667..1568503(-) (endA) [Streptococcus iners strain 29887]
MAKKNVKKQAMSLLSLLATIVVVGGGYFLNNTSSDNAANYSYYVNQSQASEFTPSQELASSVLTEKVRKQLGNSIEWNGA
GAFLINGNKTDLDASVASAPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREATGNGRTSWTPAGWHQIHDLPGEYDHA
VDRGHLLGYALIGGLAGFDASTSNPKNIAVQTAWSNQANDSTSTGQNYFETLVRKALDKNKRVRYRVTLIYAEKDDLIPV
GSHLEAKSSDGSLEFNVFVPNVQSGLSINYHSGEIHAN

Nucleotide


Download         Length: 837 bp        

>NTDB_id=794742 PW252_RS07605 WP_248049063.1 1567667..1568503(-) (endA) [Streptococcus iners strain 29887]
ATGGCGAAGAAAAATGTAAAGAAACAGGCTATGAGCCTACTAAGTTTGTTAGCTACTATTGTTGTAGTTGGTGGTGGCTA
CTTTTTAAATAATACGAGCAGCGACAATGCTGCAAACTATTCTTATTATGTCAATCAGTCGCAAGCAAGCGAGTTTACAC
CTAGCCAGGAGCTGGCTAGTTCGGTATTGACGGAGAAAGTAAGGAAACAACTTGGGAATTCCATTGAATGGAATGGAGCT
GGAGCTTTTCTGATCAACGGCAATAAGACTGATTTAGATGCTTCGGTCGCTAGTGCACCTTATGGGGATAATAAGACTAA
GACTGTGCAGGGAGAAACGGTTCCAACCGTAGCCAATGCCCTATTGGCTAAGTCAACACGTCAGTATAAGGATCGTGAAG
CAACTGGTAATGGGCGTACATCATGGACTCCTGCTGGTTGGCACCAAATTCATGATTTGCCAGGGGAATATGATCATGCA
GTTGATCGTGGACATCTGCTTGGCTATGCCTTGATTGGTGGTCTAGCTGGATTCGATGCCTCAACAAGCAATCCAAAAAA
CATAGCGGTTCAAACAGCCTGGTCTAATCAAGCCAATGATTCTACCTCAACAGGTCAGAATTATTTTGAAACCTTGGTAC
GAAAAGCCTTGGACAAGAACAAGCGTGTCCGCTACCGTGTTACCCTAATCTATGCAGAAAAAGACGACCTAATTCCAGTA
GGAAGCCATCTAGAAGCAAAATCATCCGACGGTAGCTTAGAGTTCAATGTATTTGTCCCAAATGTGCAGAGTGGCTTGAG
TATAAACTACCATAGTGGGGAAATCCATGCTAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

66.932

90.288

0.604
  endA Streptococcus pneumoniae D39

66.932

90.288

0.604
  endA Streptococcus pneumoniae R6

66.932

90.288

0.604
  endA Streptococcus pneumoniae TIGR4

66.932

90.288

0.604