Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   PW220_RS06595 Genome accession   NZ_CP118734
Coordinates   1322763..1323602 (-) Length   279 a.a.
NCBI ID   WP_248055070.1    Uniprot ID   A0AA96VH01
Organism   Streptococcus iners subsp. hyiners strain 29892     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1317763..1328602
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PW220_RS06580 (PW220_06585) - 1319855..1320376 (-) 522 WP_248055226.1 GNAT family N-acetyltransferase -
  PW220_RS06585 (PW220_06590) pheS 1320693..1321736 (-) 1044 WP_024378481.1 phenylalanine--tRNA ligase subunit alpha -
  PW220_RS06590 (PW220_06595) - 1321997..1322770 (-) 774 WP_105124185.1 hypothetical protein -
  PW220_RS06595 (PW220_06600) endA 1322763..1323602 (-) 840 WP_248055070.1 DNA/RNA non-specific endonuclease Machinery gene
  PW220_RS06600 (PW220_06605) - 1323632..1323823 (-) 192 WP_105113934.1 DNA-directed RNA polymerase subunit beta -
  PW220_RS06605 (PW220_06610) murA 1323816..1325099 (-) 1284 WP_248055069.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  PW220_RS06610 (PW220_06615) - 1325123..1325347 (-) 225 WP_105113989.1 DUF1146 family protein -
  PW220_RS06615 (PW220_06620) - 1325415..1325831 (-) 417 WP_105145390.1 F0F1 ATP synthase subunit epsilon -
  PW220_RS06620 (PW220_06625) atpD 1325842..1327248 (-) 1407 WP_105113937.1 F0F1 ATP synthase subunit beta -
  PW220_RS06625 (PW220_06630) - 1327268..1328146 (-) 879 WP_248055068.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 30223.59 Da        Isoelectric Point: 7.0738

>NTDB_id=794698 PW220_RS06595 WP_248055070.1 1322763..1323602(-) (endA) [Streptococcus iners subsp. hyiners strain 29892]
MAKKNVKKQAMSLLSLLATIVVVGGGYFLNNTSSDNAANYSYYVNQSQASEFTPSQELASSVLTEKVRKQLGNSIEWNGA
GAFLINGNKTDLDASVASAPYGDNKTKTVQGETVPTVANALLAKSTRQYKDREATGNGRTSWTPAGWHQIHDLPGEYDHA
VDRGHLLGYALIGGLAGFDASTSNPKNIAVQTAWSNQANDPTSTGQNYFETLVRKALDKNKRVRYRVTLIYAEKDDLIPV
GSHLEAKSSDGSLEFNVFVPNVQSGLSINYHSGEIMVNE

Nucleotide


Download         Length: 840 bp        

>NTDB_id=794698 PW220_RS06595 WP_248055070.1 1322763..1323602(-) (endA) [Streptococcus iners subsp. hyiners strain 29892]
ATGGCGAAGAAAAATGTAAAGAAACAGGCTATGAGCCTACTAAGTTTGTTAGCTACTATTGTTGTAGTTGGTGGTGGCTA
CTTTTTAAATAATACGAGCAGCGACAATGCTGCAAACTATTCTTATTATGTCAATCAGTCGCAAGCAAGCGAGTTTACAC
CTAGCCAGGAGCTGGCTAGTTCGGTATTGACGGAGAAAGTAAGGAAACAACTTGGGAATTCCATTGAATGGAATGGAGCT
GGAGCTTTTCTAATCAACGGCAATAAGACCGATTTAGATGCTTCAGTCGCTAGTGCACCTTATGGGGATAACAAGACTAA
GACTGTGCAAGGAGAAACGGTTCCAACGGTAGCCAATGCCCTATTGGCTAAGTCAACACGTCAGTATAAGGATCGTGAAG
CAACTGGTAATGGGCGTACATCATGGACTCCTGCTGGCTGGCACCAAATTCATGATTTGCCAGGGGAATATGATCATGCA
GTTGATCGTGGACATCTGCTTGGCTATGCTTTGATTGGTGGTCTAGCTGGATTCGATGCCTCAACAAGCAATCCAAAAAA
CATAGCGGTTCAAACAGCCTGGTCTAACCAAGCCAATGATCCTACCTCAACAGGTCAGAATTACTTTGAAACCTTGGTAC
GAAAAGCTTTGGACAAGAACAAGCGTGTCCGCTACCGTGTTACCCTAATCTATGCAGAAAAAGACGACCTAATTCCCGTA
GGAAGCCATCTAGAAGCAAAATCATCCGACGGTAGCTTAGAGTTCAATGTATTTGTTCCAAATGTGCAGAGTGGTTTGAG
TATCAATTATCATAGTGGGGAGATTATGGTGAATGAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(81-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

66.275

91.398

0.606
  endA Streptococcus pneumoniae D39

66.275

91.398

0.606
  endA Streptococcus pneumoniae R6

66.275

91.398

0.606
  endA Streptococcus pneumoniae TIGR4

66.275

91.398

0.606