Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   PUW49_RS03720 Genome accession   NZ_CP118054
Coordinates   734297..735142 (+) Length   281 a.a.
NCBI ID   WP_024051891.1    Uniprot ID   A0A412PPI9
Organism   Streptococcus anginosus strain VSI37     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 729297..740142
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS03690 (PUW49_03690) - 729519..730397 (+) 879 WP_024051896.1 F0F1 ATP synthase subunit gamma -
  PUW49_RS03695 (PUW49_03695) atpD 730432..731838 (+) 1407 WP_024051895.1 F0F1 ATP synthase subunit beta -
  PUW49_RS03700 (PUW49_03700) - 731849..732268 (+) 420 WP_003069748.1 F0F1 ATP synthase subunit epsilon -
  PUW49_RS03705 (PUW49_03705) - 732372..732602 (+) 231 WP_081333905.1 DUF1146 family protein -
  PUW49_RS03710 (PUW49_03710) murA 732640..733920 (+) 1281 WP_274995060.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  PUW49_RS03715 (PUW49_03715) - 733913..734089 (+) 177 WP_024051892.1 DNA-directed RNA polymerase subunit beta -
  PUW49_RS03720 (PUW49_03720) endA 734297..735142 (+) 846 WP_024051891.1 DNA/RNA non-specific endonuclease Machinery gene
  PUW49_RS03725 (PUW49_03725) - 735553..736697 (-) 1145 Protein_697 IS110 family transposase -
  PUW49_RS03730 (PUW49_03730) - 736949..738685 (+) 1737 WP_024051888.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 281 a.a.        Molecular weight: 30753.54 Da        Isoelectric Point: 10.4823

>NTDB_id=789668 PUW49_RS03720 WP_024051891.1 734297..735142(+) (endA) [Streptococcus anginosus strain VSI37]
MVRKKSNQKVTQSVAGLVIALVLALGGYSFSNHHSSPKPSDSTAINRSIRTNHAAPSQELAQSVVIESVKRQLKGKIEWN
GAGAFIVNENKNDLDAKVGSIPYADNKTKLVRGRTVPTVANALLSKATRQYRNREETGNGSTTWTPAGWHQVKHLSGEYH
HAVDRGHLLGYALIGNLKGFDASTSNPKNIALQTAWANQANTGHSTGQNFYETKVRKALDKNKRVRYRVTLIYANEQDLV
PVGSHIEAKSSDSSLEINVFVPNVQTGLRLNYQTGEVTVTN

Nucleotide


Download         Length: 846 bp        

>NTDB_id=789668 PUW49_RS03720 WP_024051891.1 734297..735142(+) (endA) [Streptococcus anginosus strain VSI37]
ATGGTGAGAAAGAAATCCAACCAGAAAGTAACACAAAGTGTAGCTGGTCTGGTTATAGCACTGGTTCTTGCGCTAGGAGG
TTATTCTTTTAGCAATCATCATAGTAGTCCGAAGCCTTCTGACAGCACTGCTATTAATCGAAGCATTCGGACGAATCATG
CAGCACCCAGTCAAGAATTAGCACAGAGCGTTGTAATAGAATCTGTCAAACGACAGCTCAAAGGGAAAATCGAGTGGAAT
GGCGCAGGGGCTTTTATTGTCAATGAGAATAAAAATGATTTAGATGCTAAAGTGGGCAGTATTCCTTATGCGGATAATAA
GACAAAATTGGTCAGAGGTCGAACTGTTCCGACGGTAGCAAATGCTCTTTTGTCTAAAGCTACTCGTCAGTATAGGAATC
GTGAAGAAACAGGTAATGGTTCAACAACTTGGACACCTGCTGGCTGGCATCAGGTGAAGCATTTATCGGGTGAATATCAT
CATGCAGTTGACCGTGGACATCTGCTAGGTTATGCCTTGATTGGTAACTTGAAAGGCTTTGATGCTTCGACTAGCAATCC
TAAAAATATTGCGCTGCAAACGGCTTGGGCCAATCAAGCAAATACTGGTCATTCTACGGGTCAAAATTTTTATGAAACAA
AGGTACGTAAGGCACTAGACAAAAATAAACGAGTTCGGTATCGGGTGACTTTAATTTATGCTAATGAACAGGATTTGGTG
CCGGTTGGTTCGCATATTGAAGCTAAATCAAGCGATAGTAGCTTGGAAATAAATGTCTTTGTTCCCAACGTACAGACAGG
ACTTCGGCTAAATTATCAAACAGGAGAAGTGACTGTTACCAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(112-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A412PPI9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

68

97.865

0.665
  endA Streptococcus pneumoniae D39

68

97.865

0.665
  endA Streptococcus pneumoniae R6

68

97.865

0.665
  endA Streptococcus pneumoniae TIGR4

68

97.865

0.665