Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   PDI74_RS11050 Genome accession   NZ_CP115480
Coordinates   2350703..2352853 (+) Length   716 a.a.
NCBI ID   WP_003641986.1    Uniprot ID   A0AAW3FTH1
Organism   Lactiplantibacillus plantarum strain EN6     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 2345703..2357853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PDI74_RS11020 (PDI74_11020) - 2346128..2347300 (+) 1173 WP_223843867.1 GHKL domain-containing protein -
  PDI74_RS11025 (PDI74_11025) - 2347301..2348044 (+) 744 WP_011100999.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  PDI74_RS11030 (PDI74_11030) - 2348163..2348906 (+) 744 WP_003641982.1 response regulator transcription factor -
  PDI74_RS11035 (PDI74_11035) - 2349211..2349711 (-) 501 WP_225443014.1 CPBP family intramembrane glutamic endopeptidase -
  PDI74_RS11040 (PDI74_11040) plnF 2350083..2350241 (-) 159 WP_003643811.1 two-peptide bacteriocin plantaricin EF subunit PlnF -
  PDI74_RS11045 (PDI74_11045) plnE 2350266..2350436 (-) 171 WP_003641985.1 two-peptide bacteriocin plantaricin EF subunit PlnE -
  PDI74_RS11050 (PDI74_11050) comA 2350703..2352853 (+) 2151 WP_003641986.1 peptide cleavage/export ABC transporter Regulator
  PDI74_RS11055 (PDI74_11055) - 2352869..2354245 (+) 1377 WP_003641987.1 HlyD family secretion protein -
  PDI74_RS11060 (PDI74_11060) - 2354480..2355025 (+) 546 WP_003641989.1 CPBP family intramembrane glutamic endopeptidase -
  PDI74_RS11065 (PDI74_11065) - 2355092..2355760 (+) 669 WP_003641990.1 CPBP family intramembrane glutamic endopeptidase -
  PDI74_RS11070 (PDI74_11070) - 2355847..2356527 (+) 681 WP_003641991.1 CPBP family intramembrane glutamic endopeptidase -
  PDI74_RS11075 (PDI74_11075) - 2356621..2356935 (+) 315 WP_245190559.1 hypothetical protein -
  PDI74_RS11080 (PDI74_11080) - 2356989..2357312 (+) 324 WP_245190560.1 CPBP family intramembrane glutamic endopeptidase -
  PDI74_RS11085 (PDI74_11085) - 2357450..2357653 (+) 204 WP_003641993.1 hypothetical protein -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 79952.66 Da        Isoelectric Point: 6.6531

>NTDB_id=772528 PDI74_RS11050 WP_003641986.1 2350703..2352853(+) (comA) [Lactiplantibacillus plantarum strain EN6]
MHWRNYVAQVDEMDCGVAALAMILKNYGSTTSLAYLRNIAKTSLEGTTALGLVKTAEKLGFETKAIQADMSLFEVQDLPL
PFIVHVTKNGDLQHFYVVVKTSKTHVVIADPDPTVAVISMSKERFESEWSGVALFFAPKSEYKPVKQDKGSLWGFIPSLL
KQRRLVINIVLAAVLITIISICGSYFLQAVIDTYIPNNMHSTLAVVAIGLIVFYTFQAIFTYAQNFLLAVLGQRLSIEII
LGYIRHVFELPMSFFATRRTGEIVSRFTDASKIIDALASTIVSLFLDVSIVIIMGAILVIQNMTLFWITLLSLPIYAVVI
LAFNKSFERLNQKEMESNAILSSAIIEDLHGIETVKALNGETERYQKIDSEFVDYLRKSLAYLKADTLQQALKLFIQLVL
EVVVLWVGANLVIHNQLSVGELMTYNALLAYFVNPLQNIINLQTKLQSAKVANNRLNEVYLVASEFEASRPIHNESQLNG
DIKLQGVSYRYGYGENVLDDVNLTIRQHDKVAIVGMSGSGKSTLVKLLIDFYQPNSGDVILNGFNVKNIDKHTLRTHINY
IPQEPYIFSATIEENLRLGNRSGITEKDIAKACQLALIDTDINKMAMQYQTKLDENGNTLSGGQRQRLTIARALLSPAQV
LIFDESTSGLDAITEKQLIDNLVAMTDKTIIFIAHRLSIAKRTNHIIVLHDGRVAEEGTHAALLNEHGYYYDLINS

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=772528 PDI74_RS11050 WP_003641986.1 2350703..2352853(+) (comA) [Lactiplantibacillus plantarum strain EN6]
ATGCATTGGAGAAACTATGTTGCGCAAGTTGACGAGATGGACTGTGGGGTCGCAGCTTTAGCAATGATTTTGAAAAATTA
TGGTTCGACAACATCATTGGCCTATCTAAGAAATATTGCTAAAACGAGTTTAGAAGGGACTACGGCATTAGGATTAGTAA
AAACGGCCGAAAAGTTAGGTTTTGAAACCAAAGCAATTCAAGCAGATATGAGTCTTTTCGAGGTACAAGATTTACCATTG
CCATTCATTGTGCATGTTACCAAAAATGGGGATCTACAGCATTTTTATGTCGTTGTAAAAACCTCGAAAACGCATGTCGT
GATTGCTGATCCGGACCCAACAGTTGCGGTTATCAGTATGTCAAAGGAACGGTTTGAAAGCGAATGGTCCGGAGTTGCCC
TTTTCTTTGCACCGAAGTCGGAATATAAGCCAGTTAAGCAAGATAAGGGCTCACTATGGGGATTTATTCCAAGCTTATTA
AAGCAGCGCCGACTGGTTATTAATATTGTGCTTGCTGCAGTTTTAATCACGATTATTAGTATCTGTGGGTCTTATTTCTT
ACAAGCGGTGATTGATACTTATATTCCCAATAATATGCACAGTACATTGGCAGTGGTGGCCATTGGTCTAATCGTTTTTT
ATACCTTTCAGGCTATCTTTACTTATGCCCAGAATTTTTTATTGGCGGTTTTAGGTCAACGACTTTCGATTGAAATTATT
TTAGGCTATATTCGGCACGTCTTTGAATTGCCAATGAGTTTTTTTGCCACTCGGCGGACGGGGGAAATTGTTTCGAGGTT
TACGGATGCCAGTAAGATTATTGATGCGTTAGCTAGCACAATTGTTTCGCTGTTTTTAGATGTCAGCATCGTTATTATTA
TGGGGGCAATCTTGGTAATCCAGAATATGACACTTTTTTGGATTACGTTACTCTCGTTGCCAATCTACGCGGTTGTCATC
TTAGCCTTTAATAAATCCTTTGAACGATTGAATCAAAAGGAAATGGAGAGCAATGCTATTTTGAGTTCAGCCATTATTGA
GGATCTTCATGGGATTGAAACTGTTAAGGCGCTGAATGGTGAGACGGAACGTTATCAGAAAATTGATTCAGAATTTGTTG
ATTATCTACGTAAGAGTTTAGCCTATCTTAAAGCGGATACTTTGCAACAGGCATTAAAACTGTTTATACAGTTAGTCTTA
GAAGTTGTTGTTCTATGGGTGGGCGCCAATCTCGTCATTCATAATCAGTTATCAGTTGGGGAGCTCATGACATATAATGC
TTTATTAGCCTATTTTGTTAATCCACTACAGAATATTATTAATTTGCAGACTAAGCTTCAAAGCGCTAAGGTCGCTAACA
ACCGGTTAAATGAAGTGTATTTGGTCGCTAGTGAATTTGAGGCGTCACGGCCAATTCATAATGAAAGTCAATTAAATGGT
GATATTAAGTTACAAGGGGTCAGCTATCGTTATGGTTACGGTGAAAATGTCTTAGATGATGTTAATTTGACGATTCGACA
ACATGATAAGGTTGCAATTGTGGGGATGAGTGGCTCTGGCAAGTCCACGTTAGTTAAATTGCTTATTGATTTTTATCAAC
CAAATAGTGGTGATGTCATATTGAATGGCTTCAACGTTAAGAACATCGATAAGCATACATTGCGGACCCATATTAACTAC
ATCCCGCAGGAACCATACATCTTTTCAGCGACCATTGAAGAAAATTTAAGATTAGGTAATCGCAGCGGTATTACTGAGAA
AGATATTGCGAAGGCTTGCCAATTGGCGTTAATTGATACGGATATTAATAAAATGGCCATGCAATACCAAACTAAGCTAG
ATGAGAATGGTAATACACTATCAGGTGGTCAGCGACAACGATTAACGATTGCGAGAGCGTTATTATCACCCGCTCAAGTC
TTGATATTTGATGAGTCGACGAGTGGACTGGATGCAATTACTGAAAAACAATTAATTGATAATTTAGTGGCAATGACTGA
CAAGACGATTATTTTTATTGCCCACCGGTTGTCGATTGCAAAGCGGACGAATCATATCATCGTTCTGCATGATGGTCGGG
TCGCTGAAGAGGGGACCCATGCGGCATTGTTGAATGAACATGGTTACTATTACGACTTGATCAATAGCTGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(5-140)

ABC transporter transmembrane region (ABC_membrane)

(166-436)

ABC transporter (ABC_tran)

(498-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

58.906

99.581

0.587
  comA Streptococcus pneumoniae D39

58.626

99.581

0.584
  comA Streptococcus pneumoniae R6

58.626

99.581

0.584
  comA Streptococcus pneumoniae Rx1

58.626

99.581

0.584
  comA Streptococcus pneumoniae TIGR4

58.485

99.581

0.582
  comA Streptococcus mitis SK321

58.345

99.581

0.581
  comA Streptococcus gordonii str. Challis substr. CH1

57.103

100

0.573
  comA/nlmT Streptococcus mutans UA159

54.596

100

0.547