Detailed information NTG0772450

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: PDI59_RS09505
• Genome accession: NZ_CP115478
• Coordinates: 1886275..1887318 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain HP20814-062
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1881275..1892318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PDI59_RS09475 (PDI59_09475)	-	1881696..1882952 (-)	1257	WP_001795108.1	aminopeptidase	-
PDI59_RS09480 (PDI59_09480)	-	1882955..1883155 (-)	201	WP_000180460.1	DUF1128 family protein	-
PDI59_RS09485 (PDI59_09485)	-	1883302..1883766 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
PDI59_RS09490 (PDI59_09490)	-	1883773..1884048 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
PDI59_RS09495 (PDI59_09495)	-	1884326..1885543 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
PDI59_RS09500 (PDI59_09500)	vraR	1885656..1886285 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
PDI59_RS09505 (PDI59_09505)	vraS	1886275..1887318 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
PDI59_RS09510 (PDI59_09510)	liaF	1887315..1888016 (-)	702	WP_001558031.1	cell wall-active antibiotics response protein LiaF	-
PDI59_RS09515 (PDI59_09515)	-	1888031..1888417 (-)	387	WP_001110179.1	hypothetical protein	-
PDI59_RS09520 (PDI59_09520)	map	1888634..1889392 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
PDI59_RS09525 (PDI59_09525)	-	1889923..1890909 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
PDI59_RS09530 (PDI59_09530)	-	1891340..1891753 (-)	414	WP_001557448.1	hypothetical protein	-
PDI59_RS09535 (PDI59_09535)	-	1891782..1891892 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=772450 PDI59_RS09505 WP_001017131.1 1886275..1887318(-) (vraS) [Staphylococcus aureus strain HP20814-062]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=772450 PDI59_RS09505 WP_001017131.1 1886275..1887318(-) (vraS) [Staphylococcus aureus strain HP20814-062]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1