Detailed information NTG0770171

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: QQO08_RS06630
• Genome accession: NZ_CP127024
• Coordinates: 1335059..1335832 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain CC239-MRSA-III(var.) isolate Trinidad&Tobago_2020-048_8421A
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1330059..1340832

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QQO08_RS06610 (QQO08_06610)	trmFO	1330403..1331710 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
QQO08_RS06615 (QQO08_06615)	xerC	1332127..1333023 (+)	897	WP_001015597.1	tyrosine recombinase XerC	-
QQO08_RS06620 (QQO08_06620)	hslV	1333020..1333565 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
QQO08_RS06625 (QQO08_06625)	hslU	1333631..1335034 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
QQO08_RS06630 (QQO08_06630)	codY	1335059..1335832 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
QQO08_RS06635 (QQO08_06635)	-	1335883..1335975 (+)	93	WP_001790530.1	hypothetical protein	-
QQO08_RS06640 (QQO08_06640)	rpsB	1336174..1336941 (+)	768	WP_285236857.1	30S ribosomal protein S2	-
QQO08_RS06645 (QQO08_06645)	-	1336975..1337088 (+)	114	WP_001789890.1	hypothetical protein	-
QQO08_RS06650 (QQO08_06650)	tsf	1337123..1338004 (+)	882	WP_000201387.1	translation elongation factor Ts	-
QQO08_RS06655 (QQO08_06655)	pyrH	1338141..1338863 (+)	723	WP_000057330.1	UMP kinase	-
QQO08_RS06660 (QQO08_06660)	frr	1338882..1339436 (+)	555	WP_044116402.1	ribosome recycling factor	-
QQO08_RS06665 (QQO08_06665)	-	1339813..1340583 (+)	771	WP_000473701.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=770171 QQO08_RS06630 WP_000055337.1 1335059..1335832(+) (codY) [Staphylococcus aureus strain CC239-MRSA-III(var.) isolate Trinidad&Tobago_2020-048_8421A]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=770171 QQO08_RS06630 WP_000055337.1 1335059..1335832(+) (codY) [Staphylococcus aureus strain CC239-MRSA-III(var.) isolate Trinidad&Tobago_2020-048_8421A]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428