Detailed information NTG0769996

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: QQO11_RS06650
• Genome accession: NZ_CP127019
• Coordinates: 1338221..1338994 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain CC239-MRSA-III(var.) isolate Trinidad&Tobago_2020-009_371M
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1333221..1343994

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QQO11_RS06630 (QQO11_06630)	trmFO	1333565..1334872 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
QQO11_RS06635 (QQO11_06635)	xerC	1335289..1336185 (+)	897	WP_001015597.1	tyrosine recombinase XerC	-
QQO11_RS06640 (QQO11_06640)	hslV	1336182..1336727 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
QQO11_RS06645 (QQO11_06645)	hslU	1336793..1338196 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
QQO11_RS06650 (QQO11_06650)	codY	1338221..1338994 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
QQO11_RS06655 (QQO11_06655)	-	1339045..1339137 (+)	93	WP_001790530.1	hypothetical protein	-
QQO11_RS06660 (QQO11_06660)	rpsB	1339336..1340103 (+)	768	WP_285236857.1	30S ribosomal protein S2	-
QQO11_RS06665 (QQO11_06665)	-	1340137..1340250 (+)	114	WP_001789890.1	hypothetical protein	-
QQO11_RS06670 (QQO11_06670)	tsf	1340285..1341166 (+)	882	WP_000201387.1	translation elongation factor Ts	-
QQO11_RS06675 (QQO11_06675)	pyrH	1341303..1342025 (+)	723	WP_000057330.1	UMP kinase	-
QQO11_RS06680 (QQO11_06680)	frr	1342044..1342598 (+)	555	WP_044116402.1	ribosome recycling factor	-
QQO11_RS06685 (QQO11_06685)	-	1342971..1343741 (+)	771	WP_000473701.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=769996 QQO11_RS06650 WP_000055337.1 1338221..1338994(+) (codY) [Staphylococcus aureus strain CC239-MRSA-III(var.) isolate Trinidad&Tobago_2020-009_371M]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=769996 QQO11_RS06650 WP_000055337.1 1338221..1338994(+) (codY) [Staphylococcus aureus strain CC239-MRSA-III(var.) isolate Trinidad&Tobago_2020-009_371M]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428