Detailed information NTG0769908

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: QQO09_RS05845
• Genome accession: NZ_CP127017
• Coordinates: 1204419..1205192 (+)
• Length: 257 a.a.
• NCBI ID: WP_000055337.1
• Uniprot ID: P63843
• Organism: Staphylococcus aureus strain CC8-MSSA (PVL+) isolate Trinidad&Tobago_2020-042_7641M
• Function: repression of comK (predicted from homology) Competence regulation

Genomic Context

Location: 1199419..1210192

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QQO09_RS05825 (QQO09_05825)	trmFO	1199763..1201070 (+)	1308	WP_000195254.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
QQO09_RS05830 (QQO09_05830)	xerC	1201487..1202383 (+)	897	WP_001015597.1	tyrosine recombinase XerC	-
QQO09_RS05835 (QQO09_05835)	hslV	1202380..1202925 (+)	546	WP_000072681.1	ATP-dependent protease subunit HslV	-
QQO09_RS05840 (QQO09_05840)	hslU	1202991..1204394 (+)	1404	WP_000379054.1	ATP-dependent protease ATPase subunit HslU	-
QQO09_RS05845 (QQO09_05845)	codY	1204419..1205192 (+)	774	WP_000055337.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
QQO09_RS05850 (QQO09_05850)	-	1205243..1205335 (+)	93	WP_001790530.1	hypothetical protein	-
QQO09_RS05855 (QQO09_05855)	rpsB	1205534..1206301 (+)	768	WP_000268484.1	30S ribosomal protein S2	-
QQO09_RS05860 (QQO09_05860)	-	1206335..1206448 (+)	114	WP_001789890.1	hypothetical protein	-
QQO09_RS05865 (QQO09_05865)	tsf	1206483..1207364 (+)	882	WP_000201387.1	translation elongation factor Ts	-
QQO09_RS05870 (QQO09_05870)	pyrH	1207501..1208223 (+)	723	WP_000057330.1	UMP kinase	-
QQO09_RS05875 (QQO09_05875)	frr	1208242..1208796 (+)	555	WP_285239032.1	ribosome recycling factor	-
QQO09_RS05880 (QQO09_05880)	-	1209169..1209939 (+)	771	WP_000473705.1	isoprenyl transferase	-

Sequence

Protein

• Length: 257 a.a.
• Molecular weight: 28755.13 Da
• Isoelectric Point: 6.0680

>NTDB_id=769908 QQO09_RS05845 WP_000055337.1 1204419..1205192(+) (codY) [Staphylococcus aureus strain CC8-MSSA (PVL+) isolate Trinidad&Tobago_2020-042_7641M]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide

• Length: 774 bp

>NTDB_id=769908 QQO09_RS05845 WP_000055337.1 1204419..1205192(+) (codY) [Staphylococcus aureus strain CC8-MSSA (PVL+) isolate Trinidad&Tobago_2020-042_7641M]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

• CodY GAF-like domain (CodY) (2-178)

• CodY helix-turn-helix domain (HTH_CodY) (198-255)

3D structure

• AlphaFold DB: P63843

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Bacillus subtilis subsp. subtilis str. 168	64.202	100	0.642
codY	Lactococcus lactis subsp. lactis strain DGCC12653	42.802	100	0.428