Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   QPR37_RS10680 Genome accession   NZ_CP126631
Coordinates   2167410..2168183 (-) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain 33-40     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2162410..2173183
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QPR37_RS10645 (QPR37_10645) - 2162654..2163424 (-) 771 WP_000473705.1 isoprenyl transferase -
  QPR37_RS10650 (QPR37_10650) frr 2163797..2164351 (-) 555 WP_001280006.1 ribosome recycling factor -
  QPR37_RS10655 (QPR37_10655) pyrH 2164370..2165092 (-) 723 WP_000057330.1 UMP kinase -
  QPR37_RS10660 (QPR37_10660) tsf 2165229..2166110 (-) 882 WP_000201387.1 translation elongation factor Ts -
  QPR37_RS10665 (QPR37_10665) - 2166145..2166258 (-) 114 WP_001789890.1 hypothetical protein -
  QPR37_RS10670 (QPR37_10670) rpsB 2166292..2167068 (-) 777 WP_063651283.1 30S ribosomal protein S2 -
  QPR37_RS10675 (QPR37_10675) - 2167267..2167359 (-) 93 WP_259378595.1 hypothetical protein -
  QPR37_RS10680 (QPR37_10680) codY 2167410..2168183 (-) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  QPR37_RS10685 (QPR37_10685) hslU 2168208..2169611 (-) 1404 WP_063651285.1 ATP-dependent protease ATPase subunit HslU -
  QPR37_RS10690 (QPR37_10690) hslV 2169677..2170222 (-) 546 WP_072527682.1 ATP-dependent protease subunit HslV -
  QPR37_RS10695 (QPR37_10695) xerC 2170219..2171115 (-) 897 WP_001015604.1 tyrosine recombinase XerC -
  QPR37_RS10700 (QPR37_10700) trmFO 2171533..2172840 (-) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=768018 QPR37_RS10680 WP_000055337.1 2167410..2168183(-) (codY) [Staphylococcus aureus strain 33-40]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=768018 QPR37_RS10680 WP_000055337.1 2167410..2168183(-) (codY) [Staphylococcus aureus strain 33-40]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCGATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428