Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   CC22TP_RS05705 Genome accession   NZ_AP025177
Coordinates   1197998..1198771 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain TPS6281     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1192998..1203771
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CC22TP_RS05685 (TPS6281TP_10770) trmFO 1193342..1194649 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  CC22TP_RS05690 (TPS6281TP_10780) xerC 1195066..1195962 (+) 897 WP_001015609.1 tyrosine recombinase XerC -
  CC22TP_RS05695 (TPS6281TP_10790) hslV 1195959..1196504 (+) 546 WP_217654605.1 ATP-dependent protease subunit HslV -
  CC22TP_RS05700 (TPS6281TP_10800) hslU 1196570..1197973 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  CC22TP_RS05705 (TPS6281TP_10810) codY 1197998..1198771 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  CC22TP_RS05710 - 1198822..1198914 (+) 93 WP_031788481.1 hypothetical protein -
  CC22TP_RS05715 (TPS6281TP_10820) rpsB 1199113..1199880 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  CC22TP_RS05720 - 1199914..1200027 (+) 114 WP_001789890.1 hypothetical protein -
  CC22TP_RS05725 (TPS6281TP_10830) tsf 1200062..1200943 (+) 882 WP_000201387.1 translation elongation factor Ts -
  CC22TP_RS05730 (TPS6281TP_10840) pyrH 1201080..1201802 (+) 723 WP_000057330.1 UMP kinase -
  CC22TP_RS05735 (TPS6281TP_10850) frr 1201821..1202375 (+) 555 WP_001280006.1 ribosome recycling factor -
  CC22TP_RS05740 (TPS6281TP_10860) - 1202748..1203518 (+) 771 WP_000473699.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=76592 CC22TP_RS05705 WP_000055337.1 1197998..1198771(+) (codY) [Staphylococcus aureus strain TPS6281]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=76592 CC22TP_RS05705 WP_000055337.1 1197998..1198771(+) (codY) [Staphylococcus aureus strain TPS6281]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAGTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment