Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   OPT59_RS10960 Genome accession   NZ_CP125360
Coordinates   2217716..2219698 (-) Length   660 a.a.
NCBI ID   WP_003060855.1    Uniprot ID   A0ABU0A6M3
Organism   Streptococcus dysgalactiae subsp. equisimilis strain UT_120444     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2212716..2224698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OPT59_RS10935 (OPT59_10935) recA 2212736..2213872 (-) 1137 WP_003058758.1 recombinase RecA Machinery gene
  OPT59_RS10940 (OPT59_10940) cinA 2213977..2215248 (-) 1272 WP_003058772.1 competence/damage-inducible protein A Machinery gene
  OPT59_RS10945 (OPT59_10945) - 2215317..2215877 (-) 561 WP_011018314.1 DNA-3-methyladenine glycosylase I -
  OPT59_RS10950 (OPT59_10950) ruvA 2215887..2216483 (-) 597 WP_015017499.1 Holliday junction branch migration protein RuvA Machinery gene
  OPT59_RS10955 (OPT59_10955) - 2216485..2217705 (-) 1221 WP_003058727.1 MFS transporter -
  OPT59_RS10960 (OPT59_10960) hexB 2217716..2219698 (-) 1983 WP_003060855.1 DNA mismatch repair endonuclease MutL Machinery gene
  OPT59_RS10965 (OPT59_10965) hexA 2219824..2222379 (-) 2556 WP_003061429.1 DNA mismatch repair protein MutS Machinery gene
  OPT59_RS10970 (OPT59_10970) - 2222366..2222719 (-) 354 WP_003062220.1 YlbF family regulator -
  OPT59_RS10975 (OPT59_10975) argR 2222716..2223153 (-) 438 WP_003055516.1 arginine repressor -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74539.01 Da        Isoelectric Point: 5.6832

>NTDB_id=762549 OPT59_RS10960 WP_003060855.1 2217716..2219698(-) (hexB) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
MTKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQVTIDIEESGLKKIQITDNGEGMSPEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEDNHGSLLVAIGGEIETLEETSTPVGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVSFILISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISNADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSKGLYYDPQRNDFFVKESDVSEKIPESNFHNTEIDKTVKDQR
TKQFPDLGENTGFSSVKRASRSQDEITDADHPGLDLKNKQKLSQMLTRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=762549 OPT59_RS10960 WP_003060855.1 2217716..2219698(-) (hexB) [Streptococcus dysgalactiae subsp. equisimilis strain UT_120444]
ATGACAAAAATTATTGAATTACCAGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATCGATGCTAAGAGTAGCCAAGTCACCATTGATATTGAAGAGTCTGGTCTCAAAA
AGATACAGATTACGGACAATGGTGAAGGGATGTCGCCTGAAGACCTTCCTTTGAGTTTGCGGCGACATGCTACCAGTAAA
ATAAAAAGTCAAAGTGATCTCTTTCGAATTAGAACACTTGGTTTTAGGGGAGAAGCCTTACCATCGGTTGCTTCTATCAG
TAAAATCACAATAAAAACAGCTACTAAGGAAGATAATCACGGTTCTCTTTTAGTTGCTATCGGCGGAGAGATTGAAACGC
TCGAGGAAACGTCGACGCCTGTAGGTACCAAGATTAAGGTTGAAAACCTTTTTTATAACACGCCTGCTCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAGTTAGCCCATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCAGAAGTTTCTTT
CATCCTTATTAGTGATGGCCGTCAATTAACTCAGACATCAGGGACGGGGGACCTGCGGCAGGCTATTGCAGGGATTTATG
GCTTGAATACTGCCAAAAAAATGATTGCTATTTCCAATGCCGATTTGGACTTTGAAGTGTCGGGCTATGTCAGTTTACCA
GAGTTGACACGCGCCAACCGCAATTATATGACCATTTTAATCAATGGACGCTACATTAAAAATTTCTTGCTCAATCGGGC
TATTTTAGATGGTTACGGCTCTAAGTTGATGGTTGGACGTTTCCCAATTGTGGTGATTGATATTCAGATTGACCCCTATT
TGGCCGATGTCAATGTTCACCCTACTAAGCAAGAGGTCCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATTAGTACG
GCGATTTCTGAAAGTCTTAAGGAGCAAGATTTGATTCCAGATGCTCTGGAGAACTTAGCTAAATCAAGCACACGACACTT
TTCTAAACCAGAGCAAACACAACTTCCATTACAATCTAAAGGGCTTTATTATGATCCTCAAAGAAATGACTTTTTTGTTA
AAGAATCGGATGTTTCTGAAAAAATACCTGAGAGTAATTTTCATAATACAGAGATTGACAAGACTGTAAAGGATCAAAGG
ACGAAGCAGTTTCCTGATTTAGGAGAGAATACAGGATTTTCCTCAGTAAAACGTGCTAGTCGATCACAGGATGAGATAAC
TGATGCTGATCACCCTGGACTTGATTTGAAAAACAAACAGAAATTATCTCAAATGCTAACCCGTTTGGAAAATGAAGAGC
AATCAGTATTTCCCGAATTGGATTATTTTGGTCAGATGCACGGAACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATAGGTGAGGTTGACAGTAGTTT
ACAGCAGCTGTTGGTGCCCTATTTGTTTGAGTTTTCCGGCTCGGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGTATCTTCCTAGAAGTTTATGGGCACAATACTTTCATTTTGAGAGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTCTCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGTTTGGATGATTATTCAGCAAGAAATCTGCTAC
TGCAATTAGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTGTTGATTAATTTCAGTAAGGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCATACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(462-604)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.012

100

0.689