Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   OS073_RS05990 Genome accession   NZ_CP113005
Coordinates   1164958..1165644 (-) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain Galio     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1159958..1170644
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OS073_RS05970 rpsT 1160872..1161123 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  OS073_RS05975 holA 1161168..1162142 (-) 975 WP_001282562.1 DNA polymerase III subunit delta -
  OS073_RS05980 comEC 1162199..1164400 (-) 2202 WP_001807336.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  OS073_RS05985 - 1164405..1164866 (-) 462 WP_000439693.1 ComE operon protein 2 -
  OS073_RS05990 comEA 1164958..1165644 (-) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  OS073_RS05995 - 1165684..1166400 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  OS073_RS06000 rsfS 1166403..1166756 (-) 354 WP_001088022.1 ribosome silencing factor -
  OS073_RS06005 yqeK 1166757..1167341 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  OS073_RS06010 nadD 1167331..1167900 (-) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  OS073_RS06015 yhbY 1167903..1168193 (-) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  OS073_RS06020 aroE 1168197..1169003 (-) 807 WP_000666761.1 shikimate dehydrogenase -
  OS073_RS06025 yqeH 1169017..1170117 (-) 1101 WP_001280148.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=758932 OS073_RS05990 WP_001792568.1 1164958..1165644(-) (comEA) [Staphylococcus aureus strain Galio]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=758932 OS073_RS05990 WP_001792568.1 1164958..1165644(-) (comEA) [Staphylococcus aureus strain Galio]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969