Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   OM981_RS09810 Genome accession   NZ_CP110281
Coordinates   1906438..1907217 (-) Length   259 a.a.
NCBI ID   WP_000421288.1    Uniprot ID   Q81WK7
Organism   Bacillus anthracis strain BA749     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1872116..1946039 1906438..1907217 within 0


Gene organization within MGE regions


Location: 1872116..1946039
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OM981_RS09660 (OM981_09660) - 1872460..1874130 (-) 1671 WP_000823085.1 ribonuclease J -
  OM981_RS09665 (OM981_09665) dapA 1874896..1875774 (-) 879 WP_000564761.1 4-hydroxy-tetrahydrodipicolinate synthase -
  OM981_RS09670 (OM981_09670) dapG 1875786..1877018 (-) 1233 WP_000692470.1 aspartate kinase -
  OM981_RS09675 (OM981_09675) asd 1877042..1878088 (-) 1047 WP_000414849.1 aspartate-semialdehyde dehydrogenase -
  OM981_RS09680 (OM981_09680) dpaB 1878239..1878838 (-) 600 WP_001049484.1 dipicolinate synthase subunit B -
  OM981_RS09685 (OM981_09685) dpaA 1878835..1879737 (-) 903 WP_000954726.1 dipicolinic acid synthetase subunit A -
  OM981_RS09690 (OM981_09690) - 1880012..1880263 (-) 252 WP_001239752.1 YlmC/YmxH family sporulation protein -
  OM981_RS09695 (OM981_09695) - 1880390..1881631 (-) 1242 WP_000592993.1 M16 family metallopeptidase -
  OM981_RS09700 (OM981_09700) - 1881718..1882617 (-) 900 WP_000647529.1 polysaccharide deacetylase family protein -
  OM981_RS09705 (OM981_09705) pnp 1882769..1884907 (-) 2139 WP_000076733.1 polyribonucleotide nucleotidyltransferase -
  OM981_RS09710 (OM981_09710) rpsO 1885068..1885337 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  OM981_RS09715 (OM981_09715) ribF 1885438..1886409 (-) 972 WP_000766711.1 bifunctional riboflavin kinase/FAD synthetase -
  OM981_RS09720 (OM981_09720) truB 1886453..1887376 (-) 924 WP_000399357.1 tRNA pseudouridine(55) synthase TruB -
  OM981_RS09725 (OM981_09725) rbfA 1887463..1887819 (-) 357 WP_000776446.1 30S ribosome-binding factor RbfA -
  OM981_RS09730 (OM981_09730) - 1887835..1888116 (-) 282 WP_000582364.1 DUF503 domain-containing protein -
  OM981_RS09735 (OM981_09735) infB 1888113..1890173 (-) 2061 WP_000036339.1 translation initiation factor IF-2 -
  OM981_RS09740 (OM981_09740) - 1890178..1890489 (-) 312 WP_001286523.1 YlxQ family RNA-binding protein -
  OM981_RS09745 (OM981_09745) rnpM 1890490..1890762 (-) 273 WP_000071128.1 RNase P modulator RnpM -
  OM981_RS09750 (OM981_09750) nusA 1890774..1891880 (-) 1107 WP_000102609.1 transcription termination factor NusA -
  OM981_RS09755 (OM981_09755) rimP 1891898..1892368 (-) 471 WP_000359097.1 ribosome maturation factor RimP -
  OM981_RS09760 (OM981_09760) - 1892701..1897002 (-) 4302 WP_000059985.1 PolC-type DNA polymerase III -
  OM981_RS09765 (OM981_09765) - 1897127..1898827 (-) 1701 WP_000814312.1 proline--tRNA ligase -
  OM981_RS09770 (OM981_09770) rseP 1898937..1900193 (-) 1257 WP_001090228.1 RIP metalloprotease RseP -
  OM981_RS09775 (OM981_09775) dxr 1900210..1901352 (-) 1143 WP_000790359.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  OM981_RS09780 (OM981_09780) cdsA 1901376..1902167 (-) 792 WP_000813581.1 phosphatidate cytidylyltransferase -
  OM981_RS09785 (OM981_09785) uppS 1902185..1902961 (-) 777 WP_000971303.1 isoprenyl transferase -
  OM981_RS09790 (OM981_09790) frr 1903047..1903604 (-) 558 WP_000531498.1 ribosome recycling factor -
  OM981_RS09795 (OM981_09795) pyrH 1903607..1904329 (-) 723 WP_000042663.1 UMP kinase -
  OM981_RS09800 (OM981_09800) tsf 1904396..1905283 (-) 888 WP_001018581.1 translation elongation factor Ts -
  OM981_RS09805 (OM981_09805) rpsB 1905387..1906088 (-) 702 WP_000111483.1 30S ribosomal protein S2 -
  OM981_RS09810 (OM981_09810) codY 1906438..1907217 (-) 780 WP_000421288.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  OM981_RS09815 (OM981_09815) hslU 1907295..1908686 (-) 1392 WP_000550088.1 ATP-dependent protease ATPase subunit HslU -
  OM981_RS09820 (OM981_09820) hslV 1908709..1909251 (-) 543 WP_000526272.1 ATP-dependent protease proteolytic subunit HslV -
  OM981_RS09825 (OM981_09825) xerC 1909294..1910193 (-) 900 WP_001101226.1 tyrosine recombinase XerC -
  OM981_RS09830 (OM981_09830) trmFO 1910259..1911563 (-) 1305 WP_003161605.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  OM981_RS09835 (OM981_09835) topA 1911614..1913692 (-) 2079 WP_001286969.1 type I DNA topoisomerase -
  OM981_RS09840 (OM981_09840) dprA 1913837..1914585 (-) 749 Protein_1970 DNA-processing protein DprA -
  OM981_RS09845 (OM981_09845) sucD 1914793..1915695 (-) 903 WP_000115178.1 succinate--CoA ligase subunit alpha -
  OM981_RS09850 (OM981_09850) sucC 1915716..1916876 (-) 1161 WP_001020786.1 ADP-forming succinate--CoA ligase subunit beta -
  OM981_RS09855 (OM981_09855) rnhB 1917070..1917843 (-) 774 WP_001174712.1 ribonuclease HII -
  OM981_RS09860 (OM981_09860) ylqF 1917895..1918785 (-) 891 WP_000236707.1 ribosome biogenesis GTPase YlqF -
  OM981_RS09865 (OM981_09865) lepB 1918806..1919357 (-) 552 WP_000711857.1 signal peptidase I -
  OM981_RS09870 (OM981_09870) rplS 1919459..1919803 (-) 345 WP_001186516.1 50S ribosomal protein L19 -
  OM981_RS09875 (OM981_09875) trmD 1919950..1920684 (-) 735 WP_000686892.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  OM981_RS09880 (OM981_09880) rimM 1920684..1921199 (-) 516 WP_000170269.1 ribosome maturation factor RimM -
  OM981_RS09885 (OM981_09885) - 1921320..1921547 (-) 228 WP_000737398.1 KH domain-containing protein -
  OM981_RS09890 (OM981_09890) rpsP 1921562..1921834 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  OM981_RS09895 (OM981_09895) ffh 1921935..1923284 (-) 1350 WP_000863456.1 signal recognition particle protein -
  OM981_RS09900 (OM981_09900) - 1923297..1923629 (-) 333 WP_000891062.1 putative DNA-binding protein -
  OM981_RS09905 (OM981_09905) ftsY 1923762..1924751 (-) 990 WP_000007650.1 signal recognition particle-docking protein FtsY -
  OM981_RS09910 (OM981_09910) smc 1924767..1928336 (-) 3570 WP_000478985.1 chromosome segregation protein SMC -
  OM981_RS09915 (OM981_09915) rncS 1928483..1929220 (-) 738 WP_001146873.1 ribonuclease III -
  OM981_RS09920 (OM981_09920) acpP 1929279..1929512 (-) 234 WP_000786062.1 acyl carrier protein -
  OM981_RS09925 (OM981_09925) fabG 1929582..1930322 (-) 741 WP_000911782.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  OM981_RS09930 (OM981_09930) fabD 1930322..1931266 (-) 945 WP_000516958.1 ACP S-malonyltransferase -
  OM981_RS09935 (OM981_09935) plsX 1931281..1932273 (-) 993 WP_000684111.1 phosphate acyltransferase PlsX -
  OM981_RS09940 (OM981_09940) fapR 1932270..1932863 (-) 594 WP_000747352.1 transcription factor FapR -
  OM981_RS09945 (OM981_09945) recG 1932952..1935000 (-) 2049 WP_001006884.1 ATP-dependent DNA helicase RecG -
  OM981_RS09950 (OM981_09950) - 1935290..1936966 (-) 1677 WP_000027136.1 DAK2 domain-containing protein -
  OM981_RS09955 (OM981_09955) - 1936989..1937351 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  OM981_RS09960 (OM981_09960) rpmB 1937730..1937918 (+) 189 WP_000124778.1 50S ribosomal protein L28 -
  OM981_RS09965 (OM981_09965) spoVM 1937991..1938071 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  OM981_RS09970 (OM981_09970) - 1938138..1938818 (-) 681 WP_025388434.1 thiamine diphosphokinase -
  OM981_RS09975 (OM981_09975) rpe 1938918..1939562 (-) 645 WP_000589966.1 ribulose-phosphate 3-epimerase -
  OM981_RS09980 (OM981_09980) rsgA 1939565..1940446 (-) 882 WP_001113935.1 ribosome small subunit-dependent GTPase A -
  OM981_RS09985 (OM981_09985) prkC 1940715..1942688 (-) 1974 WP_000904759.1 serine/threonine protein kinase PrkC -
  OM981_RS09990 (OM981_09990) - 1942697..1943449 (-) 753 WP_000648699.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  OM981_RS09995 (OM981_09995) rlmN 1943454..1944542 (-) 1089 WP_000450543.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  OM981_RS10000 (OM981_10000) rsmB 1944547..1945881 (-) 1335 WP_001249680.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.05 Da        Isoelectric Point: 4.7947

>NTDB_id=753758 OM981_RS09810 WP_000421288.1 1906438..1907217(-) (codY) [Bacillus anthracis strain BA749]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENKELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLHELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=753758 OM981_RS09810 WP_000421288.1 1906438..1907217(-) (codY) [Bacillus anthracis strain BA749]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGTCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATCGAGAATGAGCGTATGAAACAAATGCTTGCAGAACGTCAATTCCCAGAAGAGTATACACAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAAAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCGATCGTTGGTGGCGGTGAGCGTCTAGGTACATTAGTTTTAGCTCGTCTTGGTCAAG
AGTTCTTAGATGATGATTTAATTCTTGCTGAGTACAGCTCAACTGTTGTAGGTATGGAAATTTTACGTGAAAAAGCAGAA
GAAATCGAAGAAGAAGCACGTAGCAAAGCTGTTGTTCAAATGGCGATCAGCTCATTATCTTACAGTGAATTAGAAGCAAT
CGAGCACATCTTCGAAGAATTAAACGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGACCGCGTAGGAATCACTC
GTTCGGTAATCGTAAATGCACTTCGTAAATTAGAAAGTGCTGGTGTAATTGAGTCGCGTTCTTTAGGTATGAAAGGAACA
TACATTAAAGTATTAAACGACAAATTCTTACATGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q81WK7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459