Detailed information NTG0752909

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: NUG19_RS03795
• Genome accession: NZ_CP123853
• Coordinates: 751513..754131 (-)
• Length: 872 a.a.
• NCBI ID: WP_000073352.1
• Uniprot ID: P0C1S1
• Organism: Staphylococcus aureus strain FDA209P
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 746513..759131

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NUG19_RS03780	-	747650..748468 (-)	819	WP_001103743.1	MIP/aquaporin family protein	-
NUG19_RS03785	-	748943..749485 (-)	543	WP_001077635.1	glycerol-3-phosphate responsive antiterminator	-
NUG19_RS03790	hexB	749491..751500 (-)	2010	WP_000516264.1	DNA mismatch repair endonuclease MutL	Machinery gene
NUG19_RS03795	hexA	751513..754131 (-)	2619	WP_000073352.1	DNA mismatch repair protein MutS	Machinery gene
NUG19_RS03800	thiW	754434..754925 (-)	492	WP_000842277.1	energy coupling factor transporter S component ThiW	-
NUG19_RS03805	-	754952..755317 (-)	366	WP_000282386.1	RicAFT regulatory complex protein RicA family protein	-
NUG19_RS03810	miaB	755318..756862 (-)	1545	WP_001001521.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
NUG19_RS03815	-	756996..757289 (-)	294	WP_000655669.1	MTH1187 family thiamine-binding protein	-
NUG19_RS03820	-	757383..758249 (-)	867	WP_000190140.1	2-oxoacid:ferredoxin oxidoreductase subunit beta	-

Sequence

Protein

• Length: 872 a.a.
• Molecular weight: 99903.62 Da
• Isoelectric Point: 4.6294

>NTDB_id=752909 NUG19_RS03795 WP_000073352.1 751513..754131(-) (hexA) [Staphylococcus aureus strain FDA209P]
MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNN
GYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATL
LNEITTINPNEVVINDNISDNLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVV
QYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIER
DTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQNTLVQVNQLEPLDDLLDILEQSLVEEPP
ISVKDGGLFKVGFNTQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQ
TLSNAERFITDELKEKEDIILGAEDKAIELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFS
ENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQ
IFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHEL
TTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLKMV
ENEPEINQENLNLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMTPIEALVKLSELQNQLK

Nucleotide

• Length: 2619 bp

>NTDB_id=752909 NUG19_RS03795 WP_000073352.1 751513..754131(-) (hexA) [Staphylococcus aureus strain FDA209P]
ATGTCTAATGTTACACCAATGATGCAGCAATATTTAAAAATAAAATCAGAATACCAAGATTGCTTATTATTTTTTAGACT
AGGTGATTTCTATGAAATGTTTTATGAAGATGCCAAGGAGGCATCACGTGTACTTGAAATTACTTTGACTAAAAGAGATG
CTAAAAAAGAAAATCCAATTCCGATGTGTGGTGTTCCGTATCATTCTGCAGATAGTTATATAGATACACTTGTTAATAAT
GGATATAAAGTAGCTATTTGTGAACAGATGGAAGATCCGAAACAAACGAAAGGTATGGTTAGACGTGAGGTAGTAAGAAT
TGTGACTCCAGGAACTGTGATGGAGCAAGGTGGTGTAGATGATAAACAAAATAACTATATTTTAAGTTTTGTTATGAATC
AACCTGAAATTGCGCTTAGTTACTGTGATGTTTCTACTGGCGAATTAAAGGTTACACATTTTAATGATGAAGCGACTTTA
TTAAATGAAATTACGACGATAAACCCTAACGAAGTTGTTATCAATGACAATATTTCCGATAATTTAAAAAGACAAATTAA
TATGGTGACAGAAACAATAACAGTCAGGGAAACGTTATCATCAGAAATCTATAGTGTGAATCAAACTGAACATAAATTAA
TGTATCAAGCGACACAATTATTGCTAGATTATATTCATCATACACAAAAACGTGATTTATCGCATATCGAGGATGTTGTT
CAATATGCAGCTATAGATTATATGAAAATGGATTTTTATGCTAAGAGAAACCTTGAGTTAACGGAAAGCATTCGATTAAA
ATCAAAAAAAGGAACGCTACTTTGGCTAATGGACGAAACGAAAACACCAATGGGAGCACGCCGCTTAAAACAATGGATAG
ATAGACCACTAATAAGTAAAGAACAAATTGAAGCACGATTAGATATCGTTGATGAATTTAGTGCTCATTTCATAGAAAGA
GACACCTTAAGAACATATCTTAATCAAGTGTATGATATTGAACGTCTTGTTGGGCGTGTTAGTTACGGAAATGTTAATGC
GAGAGATTTAATTCAACTTAAACATTCCATTTCTGAAATACCGAATATTAAAGCATTACTAAATTCTATGAATCAGAATA
CGCTTGTACAAGTTAATCAACTAGAACCCCTTGATGATTTACTTGATATATTAGAACAGAGTTTAGTAGAAGAACCACCA
ATTTCAGTTAAAGATGGCGGACTATTCAAAGTTGGTTTTAATACGCAATTAGATGAATATCTTGAAGCTTCAAAAAACGG
AAAAACATGGTTAGCAGAATTACAAGCCAAAGAAAGACAACGTACAGGAATAAAATCATTGAAAATAAGCTTTAATAAAG
TGTTTGGTTATTTTATAGAAATAACACGTGCCAACTTGCAAAATTTTGAACCAAGTGAATTTGGTTATATGAGGAAGCAA
ACGTTATCGAATGCTGAACGTTTTATAACTGATGAACTTAAAGAAAAAGAAGATATCATTTTAGGTGCGGAAGACAAAGC
CATCGAATTAGAATATCAATTATTTGTTCAGCTACGTGAAGAAGTTAAAAAATATACTGAACGTTTACAACAACAAGCTA
AAATTATTTCAGAGCTAGATTGTTTACAGAGCTTTGCAGAAATTGCTCAAAAATATAATTACACTAGGCCTTCATTTAGT
GAAAATAAAACATTAGAATTAGTGGAATCTAGGCACCCAGTAGTGGAAAGAGTAATGGATTATAATGACTATGTGCCTAA
TAATTGTCGATTAGATAATGAAACATTTATATATTTAATTACAGGTCCGAATATGTCTGGTAAATCGACATATATGAGAC
AAGTTGCCATAATTAGTATAATGGCCCAAATGGGAGCTTATGTCCCTTGTAAAGAGGCAGTGTTACCTATATTTGATCAA
ATATTCACTAGAATAGGTGCGGCAGATGATTTGGTTTCAGGTAAGAGTACGTTTATGGTAGAAATGCTAGAAGCACAAAA
GGCATTAACTTATGCAACAGAGGATAGTTTGATTATTTTCGATGAAATTGGACGTGGTACTTCAACGTATGACGGTTTAG
CTTTAGCGCAGGCAATGATAGAGTATGTAGCTGAAACATCGCATGCTAAAACGTTATTTTCAACACATTATCATGAATTG
ACAACATTAGATCAAGCATTACCAAGTCTAAAAAATGTTCACGTCGCTGCTAATGAATATAAAGGTGAACTTATATTCTT
GCATAAAGTCAAAGATGGTGCAGTTGACGATAGTTATGGTATTCAAGTTGCGAAATTAGCTGATTTACCTGAAAAAGTTA
TTAGCAGAGCACAAGTGATCCTAAGCGAGTTTGAAGCGTCTGCTGGTAAAAAATCATCGATATCAAATTTAAAAATGGTC
GAAAATGAACCTGAAATTAATCAAGAAAATTTAAACTTAAGTGTTGAAGAAACAACTGATACTTTATCTCAAAAAGACTT
TGAACAAGCATCATTTGATTTGTTTGAAAATGATCAAGAAAGCGAGATTGAACTACAAATTAAAAATTTGAATTTATCTA
ATATGACACCAATTGAGGCATTGGTGAAGTTAAGTGAATTACAAAATCAATTAAAATAG

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS family domain IV (MutS_IV) (412-505)

• MutS domain I (MutS_I) (5-115)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (125-237)

3D structure

• AlphaFold DB: P0C1S1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	45.455	100	0.459