Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   OCX18_RS06235 Genome accession   NZ_AP024728
Coordinates   1272086..1272859 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain 59553     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1267086..1277859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCX18_RS06215 trmFO 1267430..1268737 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  OCX18_RS06220 xerC 1269154..1270050 (+) 897 WP_001015602.1 tyrosine recombinase XerC -
  OCX18_RS06225 hslV 1270047..1270592 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  OCX18_RS06230 hslU 1270658..1272061 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  OCX18_RS06235 codY 1272086..1272859 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  OCX18_RS06240 - 1272910..1273002 (+) 93 WP_031788481.1 hypothetical protein -
  OCX18_RS06245 rpsB 1273201..1273968 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  OCX18_RS06250 - 1274002..1274115 (+) 114 WP_001789890.1 hypothetical protein -
  OCX18_RS06255 tsf 1274150..1275031 (+) 882 WP_000201387.1 translation elongation factor Ts -
  OCX18_RS06260 pyrH 1275168..1275890 (+) 723 WP_000057330.1 UMP kinase -
  OCX18_RS06265 frr 1275909..1276463 (+) 555 WP_001280006.1 ribosome recycling factor -
  OCX18_RS06270 - 1276836..1277606 (+) 771 WP_000473705.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=75014 OCX18_RS06235 WP_000055337.1 1272086..1272859(+) (codY) [Staphylococcus aureus strain 59553]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=75014 OCX18_RS06235 WP_000055337.1 1272086..1272859(+) (codY) [Staphylococcus aureus strain 59553]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACGATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGGTCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATCCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTTTTTCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGAGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCGAT
TGAACATATCTTTGAAGAACTTGGCGGTACGGAAGGCCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428

Multiple sequence alignment