Detailed information NTG0737578

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ODS73_RS10230
• Genome accession: NZ_CP107038
• Coordinates: 1964814..1965851 (-)
• Length: 345 a.a.
• NCBI ID: WP_284060547.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BM6001
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1959814..1970851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ODS73_RS10205 (ODS73_10195)	-	1960553..1961884 (-)	1332	WP_000390044.1	hemolysin family protein	-
ODS73_RS10210 (ODS73_10200)	endA	1962175..1962999 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
ODS73_RS10215 (ODS73_10205)	-	1963038..1963226 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
ODS73_RS10220 (ODS73_10210)	murA	1963219..1964502 (-)	1284	WP_284060546.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ODS73_RS10225 (ODS73_10215)	-	1964526..1964756 (-)	231	WP_000250392.1	DUF1146 family protein	-
ODS73_RS10230 (ODS73_10220)	sepM	1964814..1965851 (-)	1038	WP_284060547.1	SepM family pheromone-processing serine protease	Regulator
ODS73_RS10235 (ODS73_10225)	coaD	1965835..1966323 (-)	489	WP_001280731.1	pantetheine-phosphate adenylyltransferase	-
ODS73_RS10240 (ODS73_10230)	rsmD	1966313..1966852 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ODS73_RS10245 (ODS73_10235)	asnA	1966917..1967909 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
ODS73_RS10250 (ODS73_10240)	-	1968020..1968703 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
ODS73_RS10255 (ODS73_10245)	-	1968759..1969499 (-)	741	WP_000152692.1	RNA methyltransferase	-
ODS73_RS10260 (ODS73_10250)	-	1969533..1969811 (+)	279	WP_001174613.1	acylphosphatase	-
ODS73_RS10265 (ODS73_10255)	yidC	1969889..1970815 (+)	927	WP_000835941.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37551.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=737578 ODS73_RS10230 WP_284060547.1 1964814..1965851(-) (sepM) [Streptococcus pneumoniae strain BM6001]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNAIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=737578 ODS73_RS10230 WP_284060547.1 1964814..1965851(-) (sepM) [Streptococcus pneumoniae strain BM6001]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGCAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGCATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCCATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (231-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588