Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   P8R99_RS09880 Genome accession   NZ_CP121160
Coordinates   1888943..1889728 (+) Length   261 a.a.
NCBI ID   WP_001133183.1    Uniprot ID   P63847
Organism   Streptococcus agalactiae strain S5     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1883943..1894728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R99_RS09860 - 1884418..1885380 (-) 963 WP_000723063.1 asparaginase -
  P8R99_RS09865 - 1885449..1886831 (+) 1383 WP_000974894.1 HAD-IIB family hydrolase -
  P8R99_RS09870 - 1886887..1887339 (-) 453 WP_000080032.1 universal stress protein -
  P8R99_RS09875 - 1887606..1888817 (+) 1212 WP_000688106.1 pyridoxal phosphate-dependent aminotransferase -
  P8R99_RS09880 codY 1888943..1889728 (+) 786 WP_001133183.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  P8R99_RS09885 - 1889795..1890343 (+) 549 WP_000158742.1 isochorismatase family cysteine hydrolase -
  P8R99_RS09890 - 1890390..1891355 (-) 966 WP_000153120.1 3-hydroxyacyl-CoA dehydrogenase -
  P8R99_RS09895 - 1891523..1892173 (+) 651 WP_071659924.1 helix-turn-helix transcriptional regulator -
  P8R99_RS09900 - 1892184..1893014 (+) 831 WP_000390093.1 pyruvate, water dikinase regulatory protein -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28972.08 Da        Isoelectric Point: 4.4520

>NTDB_id=736281 P8R99_RS09880 WP_001133183.1 1888943..1889728(+) (codY) [Streptococcus agalactiae strain S5]
MPNLLEKTRKITSILQRSVDSLDAELPYNTMAAQLADIIDCNACIINGGGNLLGYAMKYKTNTDRVEEFFETKQFPDYYV
KSASRVYDTEANLSVDNDLSIFPVETKENFQDGITTIAPIYGGGMRLGTFIIWRNDKEFSDDDLILVEIASTVVGIQLLN
LQTENLEENIRKQTAVTMAINTLSYSEMKAVAAILGELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEYN

Nucleotide


Download         Length: 786 bp        

>NTDB_id=736281 P8R99_RS09880 WP_001133183.1 1888943..1889728(+) (codY) [Streptococcus agalactiae strain S5]
ATGCCGAATTTATTAGAAAAAACTAGAAAAATTACATCCATCTTACAGCGTTCCGTAGATAGCTTAGATGCCGAATTACC
ATATAATACAATGGCGGCTCAATTAGCTGATATTATTGACTGTAACGCATGTATTATTAATGGTGGTGGTAACTTACTTG
GCTATGCCATGAAATATAAAACAAACACTGACCGTGTGGAAGAATTTTTTGAAACAAAACAATTCCCAGATTACTATGTT
AAATCTGCTAGTCGTGTTTATGATACAGAAGCTAACTTATCAGTAGATAATGATTTGTCAATTTTCCCAGTTGAGACAAA
GGAAAACTTCCAAGATGGTATTACAACAATCGCTCCAATTTATGGTGGTGGAATGCGCTTGGGAACATTTATTATCTGGC
GTAATGATAAAGAATTTAGCGACGATGATTTGATTTTAGTTGAAATTGCAAGCACCGTTGTTGGTATTCAATTACTTAAC
CTTCAAACAGAAAATCTAGAAGAAAATATTCGTAAACAAACAGCGGTGACAATGGCTATCAACACTCTATCTTATTCAGA
AATGAAAGCTGTAGCTGCTATCTTAGGAGAATTAGATGGACTTGAAGGACGCCTAACGGCATCTGTTATTGCAGACCGTA
TTGGGATTACACGTTCCGTTATTGTAAATGCTCTTCGTAAATTGGAGTCTGCGGGAATCATTGAGAGTCGCTCACTCGGT
ATGAAGGGAACATACCTCAAAGTTATTAATGAAGGTATTTTTGACAAATTAAAAGAATATAATTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(201-261)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63847

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

67.433

100

0.674
  codY Bacillus subtilis subsp. subtilis str. 168

51.822

94.636

0.49