Detailed information NTG0734018

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: P4B08_RS25255
• Genome accession: NZ_CP120704
• Coordinates: 5441683..5444247 (-)
• Length: 854 a.a.
• NCBI ID: WP_003094682.1
• Uniprot ID: A0A0H2ZHB4
• Organism: Pseudomonas aeruginosa strain SE5356
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 5436683..5449247

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P4B08_RS25235 (P4B08_25245)	tpsA4	5436719..5440971 (+)	4253	Protein_5009	two-partner secretion system exoprotein TpsA4	-
P4B08_RS25255 (P4B08_25265)	clpC	5441683..5444247 (-)	2565	WP_003094682.1	ATP-dependent chaperone ClpB	Regulator
P4B08_RS25260 (P4B08_25270)	pgeF	5444403..5445131 (-)	729	WP_003123393.1	peptidoglycan editing factor PgeF	-
P4B08_RS25265 (P4B08_25275)	rluD	5445128..5446090 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
P4B08_RS25270 (P4B08_25280)	-	5446236..5447261 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
P4B08_RS25275 (P4B08_25285)	-	5447418..5447663 (+)	246	WP_003102591.1	PP0621 family protein	-
P4B08_RS25280 (P4B08_25290)	pilS	5447653..5449245 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator

Sequence

Protein

• Length: 854 a.a.
• Molecular weight: 95005.65 Da
• Isoelectric Point: 5.1331

>NTDB_id=734018 P4B08_RS25255 WP_003094682.1 5441683..5444247(-) (clpC) [Pseudomonas aeruginosa strain SE5356]
MRIDRLTSKLQLALSDAQSLAVGHDHPAIEPVHLLSALLEQQGGSIKPLLMQVGFDIAALRSGLNKELDALPKIQSPTGD
VNLSQDLARLLNQADRLAQQKGDQFISSELVLLAAMDENTRLGKLLLGQGVSRKALENAVANLRGGEAVNDPNVEESRQA
LDKYTVDMTKRAEEGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPDGLKDKRLLAL
DMGALIAGAKFRGEFEERLKAVLNELGKQEGRVILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSEEDTIAILRGLKERYEVHHGVSITDGAIIAAAKLSHRYITDRQLPDKAIDLIDEAASR
IRMEIDSKPEELDRLDRRLIQLKIEREALKKEDDEATRKRLAKLEEDIVKLEREYADLEEIWKSEKAEVQGSAQIQQKIE
QAKQEMEAARRKGDLESMARIQYQTIPDLERSLQMVDQHGKTENQLLRNKVTDEEIAEVVSKWTGIPVSKMLEGEREKLL
RMEQELHRRVIGQDEAVVAVSNAVRRSRAGLADPNRPSGSFLFLGPTGVGKTELCKALAEFLFDTEEALVRIDMSEFMEK
HSVARLIGAPPGYVGFEEGGYLTEAIRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRLTDSHGRTVDFRNTVVVMTSNL
GSAQIQELAGDREAQRAAVMDAVNAHFRPEFINRIDEVVVFEPLAREQIAGIAEIQLGRLRKRLAERELSLELSQEALDK
LIAVGFDPVYGARPLKRAIQRWIENPLAQLILAGKFAPGASISAKVEGDEIVFA

Nucleotide

• Length: 2565 bp

>NTDB_id=734018 P4B08_RS25255 WP_003094682.1 5441683..5444247(-) (clpC) [Pseudomonas aeruginosa strain SE5356]
ATGCGAATAGACCGTTTGACCAGCAAGCTGCAACTGGCGCTCTCCGACGCCCAGTCCCTGGCCGTTGGCCATGACCATCC
GGCCATCGAGCCGGTGCACCTGCTTTCCGCCCTGCTCGAGCAGCAAGGCGGTTCGATCAAGCCCCTGCTGATGCAGGTCG
GCTTCGATATCGCCGCCCTGCGCAGCGGCCTCAACAAAGAACTCGACGCGCTGCCGAAGATCCAGAGCCCGACCGGCGAC
GTGAACCTGTCCCAGGATCTCGCACGCCTGCTCAACCAGGCTGACCGCCTGGCCCAGCAGAAGGGCGACCAGTTCATCTC
CAGCGAGCTGGTATTGCTGGCCGCGATGGACGAGAACACCAGGCTCGGCAAGCTGCTGCTCGGCCAGGGCGTGTCGCGCA
AGGCGCTGGAGAATGCCGTGGCCAACCTGCGTGGCGGCGAAGCGGTGAACGACCCGAACGTCGAGGAGTCGCGCCAGGCG
CTGGACAAGTACACCGTCGACATGACCAAGCGCGCCGAGGAAGGCAAGCTCGACCCGGTGATCGGTCGCGACGACGAGAT
CCGCCGGACCATCCAGGTCCTGCAGCGGCGGACCAAGAACAACCCGGTGCTGATCGGCGAACCCGGCGTCGGCAAGACCG
CCATCGTCGAGGGCCTGGCCCAGCGCATCATCAACGGCGAAGTGCCGGACGGCCTCAAGGACAAGCGCCTGCTGGCCCTG
GACATGGGGGCGCTGATCGCCGGTGCCAAGTTCCGCGGCGAGTTCGAGGAACGCCTGAAGGCAGTCCTCAACGAACTGGG
CAAGCAGGAAGGCCGGGTCATCCTGTTCATCGACGAACTGCACACCATGGTCGGCGCCGGCAAGGCGGAAGGCGCCATGG
ACGCCGGCAACATGCTCAAGCCGGCTCTGGCGCGCGGCGAGCTGCACTGCGTCGGTGCTACTACCCTCGACGAGTATCGC
CAGTACATCGAGAAGGATGCCGCGCTGGAGCGCCGCTTCCAGAAGGTGCTGGTGGACGAACCGAGCGAGGAAGACACCAT
CGCCATCCTCCGTGGCCTCAAGGAACGCTATGAAGTGCACCACGGGGTGAGCATCACCGACGGCGCGATCATCGCCGCGG
CCAAGCTGTCGCACCGCTACATCACCGATCGGCAACTGCCGGACAAGGCCATCGACCTGATCGACGAGGCCGCCAGCCGC
ATCCGCATGGAGATCGACTCCAAGCCGGAGGAACTGGATCGTCTCGACCGTCGCCTGATCCAGCTGAAGATCGAGCGCGA
GGCGCTGAAGAAGGAAGACGACGAAGCCACCAGGAAGCGCCTGGCCAAGCTGGAGGAGGATATCGTCAAGCTCGAGCGCG
AATACGCCGACCTCGAGGAGATCTGGAAGTCCGAGAAGGCCGAGGTGCAGGGCTCGGCGCAGATCCAGCAGAAGATCGAG
CAGGCCAAGCAGGAGATGGAGGCGGCGCGGCGCAAGGGCGACCTCGAGAGCATGGCGCGCATCCAGTACCAGACCATCCC
GGACCTGGAACGCAGCCTGCAGATGGTCGACCAGCACGGCAAGACCGAGAACCAGTTGCTGCGCAACAAGGTGACCGACG
AGGAAATCGCCGAAGTGGTTTCCAAGTGGACCGGTATCCCGGTGTCGAAGATGCTCGAGGGCGAGCGCGAGAAGCTGCTG
CGCATGGAGCAGGAGCTGCATCGGCGAGTGATCGGCCAGGACGAGGCGGTAGTCGCCGTGTCCAACGCCGTGCGCCGTTC
GCGCGCCGGCCTCGCCGATCCGAACCGGCCGAGCGGCTCGTTCCTCTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGT
TGTGCAAGGCGCTGGCCGAGTTCCTCTTCGATACCGAGGAGGCGCTGGTGCGGATCGATATGTCCGAGTTCATGGAGAAA
CACTCGGTGGCCCGCCTGATCGGCGCGCCTCCGGGCTACGTCGGCTTCGAGGAAGGCGGCTACCTGACCGAGGCGATCCG
CCGCAAGCCTTACTCGGTGGTGCTGCTGGACGAGGTGGAGAAGGCCCATCCGGATGTATTCAACATTCTCCTCCAGGTGC
TCGAGGACGGACGCCTGACCGACAGTCACGGGCGTACGGTGGACTTCCGCAACACCGTGGTGGTGATGACCTCCAACCTC
GGTTCGGCACAGATCCAGGAGCTGGCCGGCGACCGCGAGGCGCAACGTGCCGCAGTGATGGACGCGGTCAATGCGCACTT
CCGTCCGGAATTCATCAACCGGATCGACGAAGTGGTGGTATTCGAGCCGCTGGCTCGCGAGCAGATCGCCGGCATCGCCG
AGATCCAGCTCGGTCGCCTGCGCAAGCGCCTGGCCGAGCGCGAGCTGAGCCTGGAACTGAGCCAGGAGGCGCTGGACAAG
CTGATCGCCGTCGGCTTCGACCCGGTCTATGGCGCACGCCCGCTGAAGCGGGCCATCCAGCGCTGGATCGAGAACCCGCT
GGCGCAACTGATCCTGGCCGGCAAATTCGCGCCGGGTGCCAGTATCTCGGCGAAGGTGGAAGGCGACGAGATCGTCTTCG
CCTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (764-842)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-334)

3D structure

• AlphaFold DB: A0A0H2ZHB4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	48.391	100	0.493
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.417	100	0.436