Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   P3U12_RS06275 Genome accession   NZ_CP120162
Coordinates   1259761..1260534 (+) Length   257 a.a.
NCBI ID   WP_000055337.1    Uniprot ID   P63843
Organism   Staphylococcus aureus strain Dog025     
Function   repression of comK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1254761..1265534
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3U12_RS06255 (P3U12_06255) trmFO 1255105..1256412 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  P3U12_RS06260 (P3U12_06260) xerC 1256829..1257725 (+) 897 WP_001015597.1 tyrosine recombinase XerC -
  P3U12_RS06265 (P3U12_06265) hslV 1257722..1258267 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  P3U12_RS06270 (P3U12_06270) hslU 1258333..1259736 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  P3U12_RS06275 (P3U12_06275) codY 1259761..1260534 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  P3U12_RS06280 (P3U12_06280) - 1260585..1260677 (+) 93 WP_320409700.1 hypothetical protein -
  P3U12_RS06285 (P3U12_06285) rpsB 1260876..1261643 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  P3U12_RS06290 (P3U12_06290) - 1261677..1261790 (+) 114 WP_320409701.1 hypothetical protein -
  P3U12_RS06295 (P3U12_06295) tsf 1261825..1262706 (+) 882 WP_000201387.1 translation elongation factor Ts -
  P3U12_RS06300 (P3U12_06300) pyrH 1262843..1263565 (+) 723 WP_000057330.1 UMP kinase -
  P3U12_RS06305 (P3U12_06305) frr 1263584..1264138 (+) 555 WP_001280004.1 ribosome recycling factor -
  P3U12_RS06310 (P3U12_06310) - 1264511..1265281 (+) 771 WP_070002588.1 isoprenyl transferase -

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 28755.13 Da        Isoelectric Point: 6.0680

>NTDB_id=731441 P3U12_RS06275 WP_000055337.1 1259761..1260534(+) (codY) [Staphylococcus aureus strain Dog025]
MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLM
EVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKVKKEKFLDELEKSK

Nucleotide


Download         Length: 774 bp        

>NTDB_id=731441 P3U12_RS06275 WP_000055337.1 1259761..1260534(+) (codY) [Staphylococcus aureus strain Dog025]
ATGAGCTTATTATCTAAAACGAGAGAGTTAAACACGTTACTTCAAAAACACAAAGGTATTGCGGTTGATTTTAAAGATGT
AGCACAAACTATTAGTAGCGTAACTGTAACAAATGTATTTATTGTATCGCGTCGAGGTAAAATTTTAGGATCGAGTCTAA
ATGAATTATTAAAAAGTCAAAGAATTATTCAAATGTTGGAAGAAAGACATATTCCAAGTGAATATACAGAACGATTAATG
GAAGTTAAACAAACAGAATCAAATATTGATATCGACAATGTATTAACAGTATTCCCACCTGAAAACAGAGAATTATTCAT
AGATAGTCGTACAACTATCTTCCCAATTTTAGGTGGAGGGGAAAGATTAGGTACATTAGTACTTGGTCGAGTACATGATG
ATTTTAATGAAAATGATTTGGTACTAGGTGAATATGCTGCTACAGTTATTGGTATGGAAATCTTACGTGAGAAGCATAGT
GAAGTAGAAAAAGAAGCGCGCGATAAAGCTGCTATTACAATGGCAATTAATTCATTATCTTATTCTGAAAAAGAAGCAAT
TGAACATATCTTTGAAGAACTAGGCGGTACGGAAGGTCTATTAATCGCATCAAAAGTTGCAGATAGAGTTGGTATTACTA
GATCTGTAATTGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTAATTGAATCACGTTCTTTAGGAATGAAAGGTACT
TTCATTAAAGTTAAAAAAGAAAAATTCTTAGATGAATTAGAAAAAAGTAAATAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63843

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

64.202

100

0.642
  codY Lactococcus lactis subsp. lactis strain DGCC12653

42.802

100

0.428