Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | NDL69_RS02675 | Genome accession | NZ_CP104548 |
| Coordinates | 517121..517783 (+) | Length | 220 a.a. |
| NCBI ID | WP_041421240.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain 10538 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 515461..559145 | 517121..517783 | within | 0 |
Gene organization within MGE regions
Location: 515461..559145
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NDL69_RS02670 (NDL69_02665) | dnaB | 515461..516864 (+) | 1404 | WP_012503477.1 | replicative DNA helicase | - |
| NDL69_RS12060 | - | 516858..516970 (-) | 113 | Protein_519 | IS5/IS1182 family transposase | - |
| NDL69_RS02675 (NDL69_02670) | pilH | 517121..517783 (+) | 663 | WP_041421240.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| NDL69_RS02680 (NDL69_02675) | pilI | 517815..518429 (+) | 615 | WP_012503479.1 | type IV pilus modification protein PilV | Machinery gene |
| NDL69_RS02685 (NDL69_02680) | pilJ | 518426..519385 (+) | 960 | WP_260247272.1 | PilW family protein | Machinery gene |
| NDL69_RS02690 (NDL69_02685) | pilK | 519364..519963 (+) | 600 | WP_260247273.1 | pilus assembly protein | Machinery gene |
| NDL69_RS02695 (NDL69_02690) | pilL | 519978..520451 (+) | 474 | WP_012503482.1 | PilX family type IV pilin | Machinery gene |
| NDL69_RS02700 (NDL69_02695) | - | 520521..520829 (-) | 309 | WP_003706588.1 | AzlD family protein | - |
| NDL69_RS02705 (NDL69_02700) | - | 520826..521537 (-) | 712 | Protein_526 | AzlC family ABC transporter permease | - |
| NDL69_RS02710 (NDL69_02705) | dut | 521703..522155 (+) | 453 | WP_003701071.1 | dUTP diphosphatase | - |
| NDL69_RS02715 (NDL69_02710) | dapC | 522227..523414 (+) | 1188 | WP_003701073.1 | succinyldiaminopimelate transaminase | - |
| NDL69_RS02720 (NDL69_02715) | yaaA | 523570..524349 (+) | 780 | WP_003687925.1 | peroxide stress protein YaaA | - |
| NDL69_RS02735 (NDL69_02730) | - | 524879..526080 (+) | 1202 | Protein_530 | tyrosine-type recombinase/integrase | - |
| NDL69_RS02740 (NDL69_02735) | - | 526436..526705 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| NDL69_RS02745 (NDL69_02740) | - | 526900..527583 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| NDL69_RS11880 | - | 527864..528130 (-) | 267 | Protein_533 | hypothetical protein | - |
| NDL69_RS02755 (NDL69_02750) | - | 528241..528456 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| NDL69_RS02760 (NDL69_02755) | - | 528508..528999 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| NDL69_RS02765 (NDL69_02760) | - | 528996..529178 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| NDL69_RS02770 (NDL69_02765) | - | 529318..530004 (-) | 687 | WP_012503754.1 | phage replication initiation protein, NGO0469 family | - |
| NDL69_RS02775 (NDL69_02770) | - | 530073..530234 (-) | 162 | WP_003702497.1 | hypothetical protein | - |
| NDL69_RS02780 (NDL69_02775) | - | 530231..530509 (-) | 279 | WP_003691529.1 | NGO1622 family putative holin | - |
| NDL69_RS02785 (NDL69_02780) | - | 530662..530994 (-) | 333 | WP_003687946.1 | hypothetical protein | - |
| NDL69_RS02790 (NDL69_02790) | - | 531215..531691 (-) | 477 | WP_012504141.1 | DUF6948 domain-containing protein | - |
| NDL69_RS02795 (NDL69_02795) | - | 531724..531924 (-) | 201 | WP_003704298.1 | hypothetical protein | - |
| NDL69_RS02800 (NDL69_02800) | - | 532123..532536 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| NDL69_RS02805 (NDL69_02805) | - | 532533..532994 (-) | 462 | WP_003687965.1 | helix-turn-helix domain-containing protein | - |
| NDL69_RS02810 (NDL69_02810) | - | 533011..533448 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| NDL69_RS02815 (NDL69_02815) | - | 533563..534279 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| NDL69_RS02820 (NDL69_02820) | - | 534354..534584 (+) | 231 | WP_020997318.1 | transcriptional regulator | - |
| NDL69_RS02825 (NDL69_02825) | - | 534664..534819 (+) | 156 | WP_003691446.1 | hypothetical protein | - |
| NDL69_RS02830 (NDL69_02830) | - | 534796..534984 (-) | 189 | WP_003698903.1 | hypothetical protein | - |
| NDL69_RS02835 (NDL69_02835) | - | 535157..535384 (+) | 228 | WP_003698261.1 | helix-turn-helix domain-containing protein | - |
| NDL69_RS02840 (NDL69_02840) | - | 535381..535518 (+) | 138 | WP_010359998.1 | hypothetical protein | - |
| NDL69_RS02845 (NDL69_02845) | - | 536063..536566 (+) | 504 | WP_010360005.1 | hypothetical protein | - |
| NDL69_RS02850 (NDL69_02850) | - | 536563..537924 (+) | 1362 | WP_003689132.1 | DnaB-like helicase C-terminal domain-containing protein | - |
| NDL69_RS02855 (NDL69_02855) | - | 537941..538171 (+) | 231 | WP_012503490.1 | hypothetical protein | - |
| NDL69_RS02860 (NDL69_02860) | - | 538263..538757 (+) | 495 | WP_041421248.1 | DUF3310 domain-containing protein | - |
| NDL69_RS02865 (NDL69_02865) | - | 539141..539290 (+) | 150 | WP_012503493.1 | hypothetical protein | - |
| NDL69_RS02870 (NDL69_02870) | - | 539319..539600 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| NDL69_RS02875 (NDL69_02875) | - | 539591..540028 (+) | 438 | WP_041421250.1 | RusA family crossover junction endodeoxyribonuclease | - |
| NDL69_RS02880 (NDL69_02880) | - | 540021..540326 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| NDL69_RS02885 (NDL69_02885) | - | 540323..540706 (+) | 384 | WP_003687982.1 | recombination protein NinB | - |
| NDL69_RS02890 (NDL69_02890) | - | 540697..541215 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| NDL69_RS02895 (NDL69_02895) | - | 541280..541702 (+) | 423 | WP_003690919.1 | hypothetical protein | - |
| NDL69_RS02900 (NDL69_02900) | - | 541702..542241 (+) | 540 | WP_003690920.1 | hypothetical protein | - |
| NDL69_RS02905 (NDL69_02905) | - | 542222..543496 (+) | 1275 | WP_003701186.1 | PBSX family phage terminase large subunit | - |
| NDL69_RS02910 (NDL69_02910) | - | 543481..545748 (+) | 2268 | WP_228369784.1 | hypothetical protein | - |
| NDL69_RS02915 (NDL69_02915) | - | 545985..547181 (+) | 1197 | WP_003687992.1 | hypothetical protein | - |
| NDL69_RS02920 (NDL69_02920) | - | 547178..548392 (+) | 1215 | WP_044270986.1 | hypothetical protein | - |
| NDL69_RS12065 | - | 548595..554504 (+) | 5910 | WP_033909227.1 | PLxRFG domain-containing protein | - |
| NDL69_RS02935 (NDL69_02935) | - | 555130..556416 (+) | 1287 | WP_071200297.1 | DUF4043 family protein | - |
| NDL69_RS02940 (NDL69_02940) | - | 556471..556944 (+) | 474 | WP_003690936.1 | hypothetical protein | - |
| NDL69_RS02945 (NDL69_02945) | - | 556950..557435 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| NDL69_RS02950 (NDL69_02950) | - | 557432..557707 (+) | 276 | WP_010358526.1 | hypothetical protein | - |
| NDL69_RS02955 (NDL69_02955) | - | 557698..558105 (+) | 408 | WP_010358525.1 | hypothetical protein | - |
| NDL69_RS02960 (NDL69_02960) | - | 558096..558257 (+) | 162 | WP_003687999.1 | hypothetical protein | - |
| NDL69_RS02965 (NDL69_02965) | - | 558294..559145 (-) | 852 | WP_260247274.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 220 a.a. Molecular weight: 24496.91 Da Isoelectric Point: 9.6166
>NTDB_id=730360 NDL69_RS02675 WP_041421240.1 517121..517783(+) (pilH) [Neisseria gonorrhoeae strain 10538]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKDGASN
NRCDFSKKGWGMLAFGDKNDNKAYDGDATDVFLRSVVLNDTDDSRINYTFNHIAFGSSQPKADRVVWTFNQNGTFGYLPD
QNLKNNSKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCRKNDTRAVCKH
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKDGASN
NRCDFSKKGWGMLAFGDKNDNKAYDGDATDVFLRSVVLNDTDDSRINYTFNHIAFGSSQPKADRVVWTFNQNGTFGYLPD
QNLKNNSKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLINSSGRVEVCRKNDTRAVCKH
Nucleotide
Download Length: 663 bp
>NTDB_id=730360 NDL69_RS02675 WP_041421240.1 517121..517783(+) (pilH) [Neisseria gonorrhoeae strain 10538]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATCGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCGACGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTACACCTTCAATCATATCG
CTTTCGGTTCGTCTCAGCCGAAAGCCGACCGTGTAGTTTGGACTTTCAACCAAAACGGGACATTCGGCTATTTGCCCGAT
CAGAATCTCAAGAATAATTCCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACGATA
CGCGCGCCGTATGCAAACATTAA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATCGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTGCGTCCAAC
AATAGATGTGACTTCAGCAAGAAGGGGTGGGGAATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCGACGGATGTTTTCCTCCGCAGCGTGGTGTTGAATGATACCGACGACAGCCGGATTAATTACACCTTCAATCATATCG
CTTTCGGTTCGTCTCAGCCGAAAGCCGACCGTGTAGTTTGGACTTTCAACCAAAACGGGACATTCGGCTATTTGCCCGAT
CAGAATCTCAAGAATAATTCCAAATTTGTTTATTCTGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGTTTC
AGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTAACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACGATA
CGCGCGCCGTATGCAAACATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
95.909 |
100 |
0.959 |