Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutS/mutS2   Type   Machinery gene
Locus tag   P1J77_RS00370 Genome accession   NZ_CP119597
Coordinates   74310..76649 (+) Length   779 a.a.
NCBI ID   WP_010922633.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 1039     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 69310..81649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1J77_RS00350 (P1J77_00350) lepB 71642..72235 (-) 594 WP_002983074.1 signal peptidase I -
  P1J77_RS00355 (P1J77_00355) rnhC 72246..73148 (-) 903 WP_010922635.1 ribonuclease HIII -
  P1J77_RS00360 (P1J77_00360) - 73305..73613 (+) 309 WP_002993251.1 hypothetical protein -
  P1J77_RS00365 (P1J77_00365) - 73616..74161 (+) 546 WP_136278122.1 CvpA family protein -
  P1J77_RS00370 (P1J77_00370) mutS/mutS2 74310..76649 (+) 2340 WP_010922633.1 endonuclease MutS2 Machinery gene
  P1J77_RS00375 (P1J77_00375) - 76653..77153 (+) 501 WP_015055998.1 phosphatase PAP2 family protein -
  P1J77_RS00380 (P1J77_00380) trxA 77216..77548 (+) 333 WP_001932060.1 thioredoxin -
  P1J77_RS00385 (P1J77_00385) - 77600..78187 (-) 588 WP_010922631.1 helix-turn-helix transcriptional regulator -
  P1J77_RS00390 (P1J77_00390) mutY 78263..79417 (-) 1155 WP_015055997.1 A/G-specific adenine glycosylase -
  P1J77_RS00395 (P1J77_00395) - 79585..79878 (+) 294 WP_002983113.1 hypothetical protein -
  P1J77_RS00400 (P1J77_00400) rpsF 80051..80341 (+) 291 WP_002983117.1 30S ribosomal protein S6 -
  P1J77_RS00405 (P1J77_00405) ssb 80363..80854 (+) 492 WP_002983122.1 single-stranded DNA-binding protein Machinery gene
  P1J77_RS00410 (P1J77_00410) rpsR 81019..81258 (+) 240 WP_002983142.1 30S ribosomal protein S18 -

Sequence

Protein


Download         Length: 779 a.a.        Molecular weight: 87803.99 Da        Isoelectric Point: 6.4851

>NTDB_id=726945 P1J77_RS00370 WP_010922633.1 74310..76649(+) (mutS/mutS2) [Streptococcus pyogenes strain 1039]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
STDLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHAFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISNDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKIAVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
HNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFSLVRVQEEQKVKNKQINVVKKADGSGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide


Download         Length: 2340 bp        

>NTDB_id=726945 P1J77_RS00370 WP_010922633.1 74310..76649(+) (mutS/mutS2) [Streptococcus pyogenes strain 1039]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTCAAGACAGAACAATC
ACAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAACTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAGAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACGCATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATTTCTAATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTGTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTGCAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CACAATAGTTTAGTTCTCTTTGATGAACTAGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCCATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGCCCCACATATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAACGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGCCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCACCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCCCCTAGAATTGGTGATGATATTATAGTGACT
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTAGCCTCGTTAGAGTCCAAGAAGAACAGAAAGTCAAAAATAAACAGATTAATGTGGTTAAAA
AGGCTGATGGTTCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCAATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGTATTGGTACAGGCGTTATTCGTGAGGG
AGTGACAAAATATCTTCGTCGTAATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGTGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

MutS domain V (MutS_V)

(324-505)

Smr domain (Smr)

(704-778)

MutS2 and Smr-associated SH3 domain (MSSS)

(633-669)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutS/mutS2 Bacillus subtilis subsp. subtilis str. 168

40.506

100

0.411