Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   PWK65_RS07455 Genome accession   NZ_CP118481
Coordinates   1457055..1457837 (-) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain 20185322     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1452055..1462837
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWK65_RS07430 (PWK65_07365) gatB 1452152..1453591 (-) 1440 WP_002988563.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
  PWK65_RS07435 (PWK65_07370) gatA 1453591..1455057 (-) 1467 WP_002988562.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  PWK65_RS07440 (PWK65_07375) gatC 1455057..1455359 (-) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  PWK65_RS07445 (PWK65_07380) - 1455591..1455815 (-) 225 WP_002988560.1 putative PEP-binding protein -
  PWK65_RS07450 (PWK65_07385) - 1456354..1456908 (-) 555 WP_002988559.1 cysteine hydrolase family protein -
  PWK65_RS07455 (PWK65_07390) codY 1457055..1457837 (-) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  PWK65_RS07460 (PWK65_07395) - 1458055..1459269 (-) 1215 WP_002988558.1 pyridoxal phosphate-dependent aminotransferase -
  PWK65_RS07465 (PWK65_07400) - 1459500..1459952 (+) 453 WP_002983265.1 universal stress protein -
  PWK65_RS07470 (PWK65_07405) - 1460075..1461463 (-) 1389 WP_397610610.1 Cof-type HAD-IIB family hydrolase -
  PWK65_RS07475 (PWK65_07410) - 1461535..1462500 (+) 966 WP_002983258.1 asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=722506 PWK65_RS07455 WP_002983278.1 1457055..1457837(-) (codY) [Streptococcus pyogenes strain 20185322]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=722506 PWK65_RS07455 WP_002983278.1 1457055..1457837(-) (codY) [Streptococcus pyogenes strain 20185322]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAACTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAATTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504