Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   PVK49_RS01985 Genome accession   NZ_CP118306
Coordinates   388033..388815 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain 20154608     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 383033..393815
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVK49_RS01965 (PVK49_01960) - 383371..384336 (-) 966 WP_047235689.1 asparaginase -
  PVK49_RS01970 (PVK49_01965) - 384408..385796 (+) 1389 WP_002992572.1 Cof-type HAD-IIB family hydrolase -
  PVK49_RS01975 (PVK49_01970) - 385918..386370 (-) 453 WP_002992571.1 universal stress protein -
  PVK49_RS01980 (PVK49_01975) - 386601..387815 (+) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  PVK49_RS01985 (PVK49_01980) codY 388033..388815 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  PVK49_RS01990 (PVK49_01985) - 388962..389516 (+) 555 WP_002983281.1 cysteine hydrolase family protein -
  PVK49_RS01995 (PVK49_01990) - 390055..390279 (+) 225 WP_002988560.1 putative PEP-binding protein -
  PVK49_RS02000 (PVK49_01995) gatC 390511..390813 (+) 303 WP_002988561.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  PVK49_RS02005 (PVK49_02000) gatA 390813..392279 (+) 1467 WP_023611911.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  PVK49_RS02010 (PVK49_02005) gatB 392279..393718 (+) 1440 WP_047235690.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=721624 PVK49_RS01985 WP_002983278.1 388033..388815(+) (codY) [Streptococcus pyogenes strain 20154608]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=721624 PVK49_RS01985 WP_002983278.1 388033..388815(+) (codY) [Streptococcus pyogenes strain 20154608]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAATTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTAACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504