Detailed information NTG0721357

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: MGCS35922_RS08970
• Genome accession: NZ_CP118097
• Coordinates: 1807912..1808694 (-)
• Length: 260 a.a.
• NCBI ID: WP_003053880.1
• Uniprot ID: A0A9X9SKT8
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1802912..1813694

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS35922_RS08940 (MGCS35922_03634)	-	1803558..1804151 (-)	594	WP_274047907.1	helix-turn-helix transcriptional regulator	-
MGCS35922_RS08945 (MGCS35922_03636)	-	1804382..1804681 (-)	300	WP_015058017.1	rhodanese-like domain-containing protein	-
MGCS35922_RS08950 (MGCS35922_03638)	-	1804674..1806326 (-)	1653	WP_084916741.1	FAD-dependent oxidoreductase	-
MGCS35922_RS08955 (MGCS35922_03640)	-	1806344..1806682 (-)	339	WP_003061685.1	rhodanese-like domain-containing protein	-
MGCS35922_RS08960 (MGCS35922_03642)	-	1806896..1807156 (+)	261	WP_003053835.1	metal-sensitive transcriptional regulator	-
MGCS35922_RS08965 (MGCS35922_03644)	-	1807223..1807774 (-)	552	WP_171841618.1	isochorismatase family cysteine hydrolase	-
MGCS35922_RS08970 (MGCS35922_03646)	codY	1807912..1808694 (-)	783	WP_003053880.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
MGCS35922_RS08975 (MGCS35922_03648)	-	1808959..1810173 (-)	1215	WP_003060547.1	pyridoxal phosphate-dependent aminotransferase	-
MGCS35922_RS08980 (MGCS35922_03650)	-	1810510..1810962 (+)	453	WP_003052566.1	universal stress protein	-
MGCS35922_RS08985 (MGCS35922_03652)	-	1811125..1812513 (-)	1389	WP_012767516.1	Cof-type HAD-IIB family hydrolase	-
MGCS35922_RS08990 (MGCS35922_03654)	-	1812586..1813551 (+)	966	WP_275926347.1	asparaginase	-

Sequence

Protein

• Length: 260 a.a.
• Molecular weight: 28748.89 Da
• Isoelectric Point: 4.4678

>NTDB_id=721357 MGCS35922_RS08970 WP_003053880.1 1807912..1808694(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVESELTIFPVESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDNEFSDEDLILVEISSTVVGIQLLN
LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEF

Nucleotide

• Length: 783 bp

>NTDB_id=721357 MGCS35922_RS08970 WP_003053880.1 1807912..1808694(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS35922]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATTACGTCTATTCTACAGCGCTCTGTAGATAGCTTGGAGACAGAACTCCC
ATATAATACGATGGCGTCTCGCTTGGCAGATATTATTGACTGTAATGCCTGCATTATCAATGGCGGAGGAACTCTACTTG
GTTATGCCATGAAATATAAAACCAACACAGACCGTGTTGAGGAATTTTTTGAAGCTAAGCAATTTCCAGATACTTATGTC
AAAGCAGCTAGCCGTGTCTACGACACTGAGGCCAATCTTTCAGTGGAAAGTGAATTAACCATTTTTCCTGTGGAATCGAA
AGACATCTATCCAGATGGTTTGACAACAATTGCACCGATTTATGGTGGAGGTATGCGTCTAGGATCTCTTATCATTTGGC
GCAACGATAATGAGTTTAGTGATGAGGACCTCATCTTGGTTGAAATTTCAAGCACGGTTGTTGGGATTCAGTTGTTAAAC
CTTCAAACAGAAAACCTGGAAGAAACGATCCGCAAGCAAACTGCTGTCAACATGGCTATTAACACCCTATCTTATTCAGA
AATGAAGGCTGTTGCAGCTATTCTTGGTGAATTGGATGGTAACGAAGGGCGTTTAACAGCTTCTGTCATTGCTGACCGTA
TTGGCATTACACGATCTGTGATCGTCAATGCCCTTCGTAAATTGGAAAGTGCTGGTATTATTGAAAGTCGCTCTCTCGGC
ATGAAGGGAACCTACCTCAAAGTTATTAATGAGGGTATTTTTGATAAATTGAAAGAATTTTAA

Domains

Predicted by InterProScan.

• CodY helix-turn-helix domain (HTH_CodY) (202-260)

• CodY GAF-like domain (CodY) (3-182)

3D structure

• AlphaFold DB: A0A9X9SKT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	66.537	98.846	0.658
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	95	0.504