Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   PUW74_RS08735 Genome accession   NZ_CP118080
Coordinates   1714733..1715518 (-) Length   261 a.a.
NCBI ID   WP_001133183.1    Uniprot ID   P63847
Organism   Streptococcus agalactiae strain VSI14     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1709733..1720518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW74_RS08715 (PUW74_08715) - 1711447..1712277 (-) 831 WP_000390093.1 pyruvate, water dikinase regulatory protein -
  PUW74_RS08720 (PUW74_08720) - 1712288..1712938 (-) 651 WP_071659924.1 helix-turn-helix transcriptional regulator -
  PUW74_RS08725 (PUW74_08725) - 1713091..1714071 (+) 981 WP_267471247.1 3-hydroxyacyl-CoA dehydrogenase -
  PUW74_RS08730 (PUW74_08730) - 1714118..1714666 (-) 549 WP_000158740.1 isochorismatase family cysteine hydrolase -
  PUW74_RS08735 (PUW74_08735) codY 1714733..1715518 (-) 786 WP_001133183.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  PUW74_RS08740 (PUW74_08740) - 1715644..1716855 (-) 1212 WP_000688108.1 pyridoxal phosphate-dependent aminotransferase -
  PUW74_RS08745 (PUW74_08745) - 1717122..1717574 (+) 453 WP_000080032.1 universal stress protein -
  PUW74_RS08750 (PUW74_08750) - 1717630..1719012 (-) 1383 WP_000974899.1 HAD-IIB family hydrolase -
  PUW74_RS08755 (PUW74_08755) - 1719081..1720043 (+) 963 WP_000723059.1 asparaginase domain-containing protein -

Sequence

Protein


Download         Length: 261 a.a.        Molecular weight: 28972.08 Da        Isoelectric Point: 4.4520

>NTDB_id=721250 PUW74_RS08735 WP_001133183.1 1714733..1715518(-) (codY) [Streptococcus agalactiae strain VSI14]
MPNLLEKTRKITSILQRSVDSLDAELPYNTMAAQLADIIDCNACIINGGGNLLGYAMKYKTNTDRVEEFFETKQFPDYYV
KSASRVYDTEANLSVDNDLSIFPVETKENFQDGITTIAPIYGGGMRLGTFIIWRNDKEFSDDDLILVEIASTVVGIQLLN
LQTENLEENIRKQTAVTMAINTLSYSEMKAVAAILGELDGLEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEYN

Nucleotide


Download         Length: 786 bp        

>NTDB_id=721250 PUW74_RS08735 WP_001133183.1 1714733..1715518(-) (codY) [Streptococcus agalactiae strain VSI14]
ATGCCGAATTTATTAGAAAAAACTAGAAAAATTACATCCATCTTACAGCGTTCCGTAGATAGCTTAGATGCCGAACTACC
ATATAATACAATGGCGGCTCAATTAGCTGATATTATTGACTGTAACGCATGTATTATTAATGGTGGTGGTAACTTACTTG
GCTATGCCATGAAATATAAAACAAACACTGACCGTGTGGAAGAATTTTTTGAAACAAAACAATTCCCAGATTACTATGTT
AAATCTGCTAGTCGTGTTTATGATACAGAAGCTAACTTATCAGTAGATAATGATTTGTCAATTTTCCCAGTTGAGACAAA
GGAAAACTTCCAAGATGGTATTACAACAATCGCTCCAATTTATGGTGGTGGAATGCGCTTGGGAACATTTATTATCTGGC
GTAATGATAAAGAATTTAGCGACGATGATTTGATTTTAGTTGAAATTGCAAGCACCGTTGTTGGTATTCAATTACTTAAC
CTTCAAACAGAAAATCTAGAAGAAAATATTCGTAAACAAACAGCGGTGACAATGGCTATCAACACTCTATCTTATTCAGA
AATGAAAGCTGTAGCTGCTATCTTAGGAGAATTAGATGGACTTGAAGGACGCCTAACGGCATCTGTTATTGCAGACCGTA
TTGGAATTACACGTTCCGTTATTGTAAATGCTCTTCGTAAATTGGAGTCTGCGGGAATCATTGAGAGCCGCTCACTCGGT
ATGAAGGGAACATACCTCAAAGTTATTAACGAAGGTATTTTTGACAAATTAAAAGAATATAATTAA

Domains

Predicted by InterProScan.

CodY GAF-like domain (CodY)

(3-182)

CodY helix-turn-helix domain (HTH_CodY)

(201-261)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63847

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

67.433

100

0.674
  codY Bacillus subtilis subsp. subtilis str. 168

51.822

94.636

0.49