Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   PUW49_RS09040 Genome accession   NZ_CP118054
Coordinates   1775138..1775926 (-) Length   262 a.a.
NCBI ID   WP_024052675.1    Uniprot ID   A0A413KRA2
Organism   Streptococcus anginosus strain VSI37     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1770138..1780926
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PUW49_RS09020 (PUW49_09020) gatA 1770472..1771938 (-) 1467 WP_024052672.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  PUW49_RS09025 (PUW49_09025) gatC 1771938..1772240 (-) 303 WP_003026120.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  PUW49_RS09030 (PUW49_09030) aspS 1772317..1774056 (-) 1740 WP_024052673.1 aspartate--tRNA ligase -
  PUW49_RS09035 (PUW49_09035) - 1774563..1775138 (-) 576 WP_070815102.1 isochorismatase family cysteine hydrolase -
  PUW49_RS09040 (PUW49_09040) codY 1775138..1775926 (-) 789 WP_024052675.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  PUW49_RS09045 (PUW49_09045) - 1776167..1777381 (-) 1215 WP_024052676.1 pyridoxal phosphate-dependent aminotransferase -
  PUW49_RS09050 (PUW49_09050) - 1777533..1777985 (+) 453 WP_020999785.1 universal stress protein -
  PUW49_RS09055 (PUW49_09055) - 1778031..1779419 (-) 1389 WP_024052677.1 Cof-type HAD-IIB family hydrolase -
  PUW49_RS09060 (PUW49_09060) - 1779484..1780446 (+) 963 WP_024052678.1 asparaginase -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 29693.01 Da        Isoelectric Point: 5.0797

>NTDB_id=720918 PUW49_RS09040 WP_024052675.1 1775138..1775926(-) (codY) [Streptococcus anginosus strain VSI37]
MANLLAKTRKITSILRRSDERLQDELPYNAITQQLAEIMDCNACIVNSKGRLLGYFMRYKTNNDRVEAFYQTKIFPEEYV
RTANLMYDTEANLPVNHDLSIFPVETKDEFPDGLTTISPIHVSGIRLGTLIVWRNDKEFDDDDLILVEIASTVVGIQLLN
FQREEDEKNIRRRAAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVLIPDVFEEIKKRDY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=720918 PUW49_RS09040 WP_024052675.1 1775138..1775926(-) (codY) [Streptococcus anginosus strain VSI37]
ATGGCAAACTTATTAGCAAAAACACGAAAAATTACATCTATTTTGCGTCGTTCAGATGAGCGATTACAGGATGAATTACC
TTACAATGCAATTACCCAGCAGCTAGCTGAAATTATGGATTGCAATGCTTGTATTGTAAACAGCAAGGGGCGTCTTTTGG
GGTATTTCATGCGCTACAAGACGAACAATGACCGTGTGGAAGCATTTTATCAAACGAAAATCTTCCCAGAAGAATATGTT
CGCACAGCGAATTTAATGTATGACACAGAAGCCAATCTTCCTGTCAATCATGATTTGTCAATTTTTCCAGTTGAAACCAA
AGATGAATTTCCAGACGGCTTGACGACGATTTCGCCTATTCATGTTTCAGGGATTCGCTTAGGAACTTTGATTGTTTGGC
GCAATGATAAAGAATTTGATGATGATGATTTGATTTTGGTTGAAATTGCAAGTACAGTGGTTGGTATTCAGTTGCTCAAC
TTCCAACGAGAAGAAGATGAAAAAAATATTCGTCGCAGAGCAGCGGTAACCATGGCTGTAAATACTTTGTCTTATTCAGA
ATTACGAGCTGTTTCAGCTATTTTAGGTGAATTAAATGGCAATGAAGGTCAATTGACAGCATCGGTCATTGCGGATCGTA
TTGGCATTACTCGCTCGGTAATTGTCAATGCTCTGCGTAAACTAGAGAGTGCAGGCATTATTGAAAGTCGTTCTTTAGGA
ATGAAAGGAACCTATCTTAAAGTCCTTATTCCCGATGTCTTTGAAGAGATTAAAAAGAGAGATTACTGA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-258)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A413KRA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

61.45

100

0.615
  codY Bacillus subtilis subsp. subtilis str. 168

50.813

93.893

0.477