Detailed information NTG0071842

Bioinformatically predicted

Overview

• Name: rcrP
• Type: Regulator
• Locus tag: EL277_RS12435
• Genome accession: NZ_AP018936
• Coordinates: 1848270..1849091 (-)
• Length: 273 a.a.
• NCBI ID: WP_000601684.1
• Uniprot ID: A0A4M9J287
• Organism: Streptococcus pneumoniae strain NU83127
• Function: regulate competence (predicted from homology) Competence regulation

Genomic Context

Location: 1843270..1854091

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL277_RS09795 (SPNU_1853)	-	1843762..1844079 (-)	318	WP_000615765.1	thioredoxin family protein	-
EL277_RS09800 (SPNU_1854)	-	1844076..1844375 (-)	300	WP_001013974.1	DUF4651 domain-containing protein	-
EL277_RS12625	-	1844469..1844600 (+)	132	WP_001811306.1	hypothetical protein	-
EL277_RS12425	-	1844625..1844687 (-)	63	WP_219335539.1	hypothetical protein	-
EL277_RS09805	-	1844712..1844903 (-)	192	WP_000291826.1	cell wall-binding protein	-
EL277_RS09810 (SPNU_1855)	-	1845064..1845738 (-)	675	WP_000725749.1	LiaF transmembrane domain-containing protein	-
EL277_RS09815 (SPNU_1856)	-	1845744..1846190 (-)	447	WP_000776589.1	LytTR family DNA-binding domain-containing protein	-
EL277_RS09820 (SPNU_1857)	-	1846304..1846807 (-)	504	WP_000800931.1	phosphatase PAP2 family protein	-
EL277_RS09825 (SPNU_1858)	-	1846804..1847166 (-)	363	WP_000078805.1	DUF2200 domain-containing protein	-
EL277_RS12430 (SPNU_1859)	rcrQ	1847232..1848263 (-)	1032	WP_000506419.1	ABC transporter ATP-binding protein/permease	Regulator
EL277_RS12435 (SPNU_1860)	rcrP	1848270..1849091 (-)	822	WP_000601684.1	ABC transporter permease	Regulator
EL277_RS09835 (SPNU_1861)	-	1849108..1849579 (-)	472	Protein_1835	MarR family winged helix-turn-helix transcriptional regulator	-
EL277_RS09845 (SPNU_1862)	-	1849703..1850419 (-)	717	WP_000532876.1	YebC/PmpR family DNA-binding transcriptional regulator	-
EL277_RS09855 (SPNU_1863)	ply	1851300..1852715 (-)	1416	WP_001284361.1	cholesterol-dependent cytolysin pneumolysin	-
EL277_RS09860 (SPNU_1864)	-	1852726..1853136 (-)	411	WP_000595758.1	hypothetical protein	-
EL277_RS09865 (SPNU_1865)	-	1853129..1853737 (-)	609	WP_000083614.1	hypothetical protein	-

Sequence

Protein

• Length: 273 a.a.
• Molecular weight: 30566.08 Da
• Isoelectric Point: 5.9310

>NTDB_id=71842 EL277_RS12435 WP_000601684.1 1848270..1849091(-) (rcrP) [Streptococcus pneumoniae strain NU83127]
MILLAILFTCFSVYLELEVPTYISKITDLLGSQETNLDELWQSASMMMGMSFLAFLSVVAVGFFASRVAASYTSRLRSDI
FNRVLDYSQTEIKKFSIPSLLTRTTNDITQVQMLITMGLQVVTRGSIMAIWAIGKILGHSEYWLWAVLVAVIINVLMTTV
LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNLFVNRLMAILNPIMMGISSGLSV
AIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM

Nucleotide

• Length: 822 bp

>NTDB_id=71842 EL277_RS12435 WP_000601684.1 1848270..1849091(-) (rcrP) [Streptococcus pneumoniae strain NU83127]
ATGATTTTACTAGCCATTCTCTTTACTTGCTTTTCGGTCTATCTAGAGTTGGAAGTGCCGACCTATATCTCGAAAATTAC
GGATTTGCTAGGTAGTCAAGAAACTAATTTAGATGAGTTGTGGCAGTCGGCAAGCATGATGATGGGAATGTCCTTTCTTG
CCTTCTTGTCCGTAGTTGCAGTTGGATTTTTTGCATCCCGAGTGGCGGCTTCTTATACTAGTAGGCTGAGAAGTGATATT
TTTAACCGAGTTTTGGATTACTCGCAGACAGAGATTAAGAAATTTTCAATTCCTAGCCTCTTGACGCGTACTACCAATGA
CATTACTCAAGTTCAAATGTTGATTACTATGGGCTTGCAAGTGGTAACGCGTGGTTCAATTATGGCTATCTGGGCTATTG
GGAAGATTTTAGGTCATTCAGAATACTGGCTCTGGGCCGTACTTGTGGCAGTGATTATCAACGTCCTGATGACGACCGTT
TTGATGACGCTAGCCTTTCCAAAACAGTCCTTGATTCAGGGGCTGACAGATAAACTGAACAGTATCACTCGTGAGAGTTT
AACAGGTATTCGTGTCGTTCGTGCCTACAATGCAGAGGATTATCAAAATGAAAAATTTGCAGCAGTAAATGATGAATTGA
CCCGTTTGAATTTGTTTGTCAACCGTCTTATGGCTATTTTGAATCCTATCATGATGGGGATTTCAAGTGGTTTGAGTGTG
GCGATTTACTGGATTGGGGCCTATGTGATTAACGACGCTGCTCCGATAGCGCGTCTGCCTCTCTTTAGTGACATGATTGT
TTTCATGTCTTATGCCATGTAG

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (3-272)

3D structure

• AlphaFold DB: A0A4M9J287

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rcrP	Streptococcus mutans UA159	57.544	100	0.601