Detailed information NTG0717537

Bioinformatically predicted

Overview

• Name: codY
• Type: Regulator
• Locus tag: MGGS36055_RS09260
• Genome accession: NZ_CP117286
• Coordinates: 1842681..1843463 (-)
• Length: 260 a.a.
• NCBI ID: WP_003053880.1
• Uniprot ID: A0A9X9SKT8
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1837681..1848463

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGGS36055_RS09230 (MGGS36055_03718)	-	1838327..1838920 (-)	594	WP_274047907.1	helix-turn-helix transcriptional regulator	-
MGGS36055_RS09235 (MGGS36055_03720)	-	1839151..1839450 (-)	300	WP_042357984.1	rhodanese-like domain-containing protein	-
MGGS36055_RS09240 (MGGS36055_03722)	-	1839443..1841095 (-)	1653	WP_015017366.1	FAD-dependent oxidoreductase	-
MGGS36055_RS09245 (MGGS36055_03724)	-	1841113..1841451 (-)	339	WP_012767514.1	rhodanese-like domain-containing protein	-
MGGS36055_RS09250 (MGGS36055_03726)	-	1841665..1841925 (+)	261	WP_003053835.1	metal-sensitive transcriptional regulator	-
MGGS36055_RS09255 (MGGS36055_03728)	-	1841992..1842543 (-)	552	WP_171841618.1	isochorismatase family cysteine hydrolase	-
MGGS36055_RS09260 (MGGS36055_03730)	codY	1842681..1843463 (-)	783	WP_003053880.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
MGGS36055_RS09265 (MGGS36055_03732)	-	1843728..1844942 (-)	1215	WP_003060547.1	pyridoxal phosphate-dependent aminotransferase	-
MGGS36055_RS09270 (MGGS36055_03734)	-	1845279..1845731 (+)	453	WP_003052566.1	universal stress protein	-
MGGS36055_RS09275 (MGGS36055_03736)	-	1845894..1847282 (-)	1389	WP_012767516.1	Cof-type HAD-IIB family hydrolase	-
MGGS36055_RS09280 (MGGS36055_03738)	-	1847355..1848320 (+)	966	WP_003053845.1	asparaginase	-

Sequence

Protein

• Length: 260 a.a.
• Molecular weight: 28748.89 Da
• Isoelectric Point: 4.4678

>NTDB_id=717537 MGGS36055_RS09260 WP_003053880.1 1842681..1843463(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVESELTIFPVESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDNEFSDEDLILVEISSTVVGIQLLN
LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEF

Nucleotide

• Length: 783 bp

>NTDB_id=717537 MGGS36055_RS09260 WP_003053880.1 1842681..1843463(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain MGGS36055]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATTACGTCTATTCTACAGCGCTCTGTAGATAGCTTGGAGACAGAACTCCC
ATATAATACGATGGCGTCTCGCTTGGCAGATATTATTGACTGTAATGCCTGCATTATCAATGGCGGAGGAACCCTACTTG
GTTATGCCATGAAATATAAAACCAACACAGACCGTGTTGAGGAATTTTTTGAAGCTAAGCAATTTCCAGATACTTATGTC
AAAGCAGCTAGCCGTGTCTACGACACTGAGGCCAATCTTTCAGTGGAAAGTGAATTAACCATTTTTCCTGTGGAATCGAA
AGACATCTATCCAGATGGTTTGACAACAATTGCACCGATTTATGGTGGAGGTATGCGTCTAGGATCTCTTATCATTTGGC
GCAACGATAATGAGTTTAGTGATGAGGACCTCATCTTGGTTGAAATTTCAAGCACGGTTGTTGGGATTCAGTTGTTAAAC
CTTCAAACAGAAAACCTGGAAGAAACGATCCGCAAGCAAACTGCTGTCAACATGGCTATTAACACCCTATCTTATTCAGA
AATGAAGGCTGTTGCAGCTATTCTTGGTGAATTGGATGGTAACGAAGGGCGTTTAACAGCTTCTGTCATTGCTGACCGTA
TTGGCATTACACGATCTGTGATCGTCAATGCCCTTCGTAAATTGGAAAGTGCTGGTATTATTGAAAGTCGCTCTCTCGGC
ATGAAGGGAACCTACCTCAAAGTTATTAATGAGGGTATTTTTGATAAATTGAAAGAATTTTAA

Domains

Predicted by InterProScan.

• CodY helix-turn-helix domain (HTH_CodY) (202-260)

• CodY GAF-like domain (CodY) (3-182)

3D structure

• AlphaFold DB: A0A9X9SKT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	66.537	98.846	0.658
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	95	0.504