NTDB

Overview

Name	codY	Type	Regulator
Locus tag	MGCS36083_RS09220	Genome accession	NZ_CP117285
Coordinates	1847339..1848121 (-)	Length	260 a.a.
NCBI ID	WP_003053880.1	Uniprot ID	A0A9X9SKT8
Organism	Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083
Function	repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1842339..1853121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGCS36083_RS09190 (MGCS36083_03732)	-	1842985..1843578 (-)	594	WP_274047907.1	helix-turn-helix transcriptional regulator	-
MGCS36083_RS09195 (MGCS36083_03734)	-	1843809..1844108 (-)	300	WP_015058017.1	rhodanese-like domain-containing protein	-
MGCS36083_RS09200 (MGCS36083_03736)	-	1844101..1845753 (-)	1653	WP_084916741.1	FAD-dependent oxidoreductase	-
MGCS36083_RS09205 (MGCS36083_03738)	-	1845771..1846109 (-)	339	WP_003061685.1	rhodanese-like domain-containing protein	-
MGCS36083_RS09210 (MGCS36083_03740)	-	1846323..1846583 (+)	261	WP_003053835.1	metal-sensitive transcriptional regulator	-
MGCS36083_RS09215 (MGCS36083_03742)	-	1846650..1847201 (-)	552	WP_171841618.1	cysteine hydrolase family protein	-
MGCS36083_RS09220 (MGCS36083_03744)	codY	1847339..1848121 (-)	783	WP_003053880.1	GTP-sensing pleiotropic transcriptional regulator CodY	Regulator
MGCS36083_RS09225 (MGCS36083_03746)	-	1848386..1849600 (-)	1215	WP_003060547.1	pyridoxal phosphate-dependent aminotransferase	-
MGCS36083_RS09230 (MGCS36083_03748)	-	1849937..1850389 (+)	453	WP_003052566.1	universal stress protein	-
MGCS36083_RS09235 (MGCS36083_03750)	-	1850552..1851940 (-)	1389	WP_012767516.1	Cof-type HAD-IIB family hydrolase	-
MGCS36083_RS09240 (MGCS36083_03752)	-	1852013..1852978 (+)	966	WP_003053845.1	asparaginase	-

Sequence

Protein

Download Length: 260 a.a. Molecular weight: 28748.89 Da Isoelectric Point: 4.4678

                                >NTDB_id=717434 MGCS36083_RS09220 WP_003053880.1 1847339..1848121(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083]

MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV

KAASRVYDTEANLSVESELTIFPVESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDNEFSDEDLILVEISSTVVGIQLLN

LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG

MKGTYLKVINEGIFDKLKEF

Nucleotide

Download Length: 783 bp

                                >NTDB_id=717434 MGCS36083_RS09220 WP_003053880.1 1847339..1848121(-) (codY) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083]

ATGCCTAACTTATTAGAAAAAACTCGTAAAATTACGTCTATTCTACAGCGCTCTGTAGATAGCTTGGAGACAGAACTCCC

ATATAATACGATGGCGTCTCGCTTGGCAGATATTATTGACTGTAATGCCTGCATTATCAATGGCGGAGGAACTCTACTTG

GTTATGCCATGAAATATAAAACCAACACAGACCGTGTTGAGGAATTTTTTGAAGCTAAGCAATTTCCAGATACTTATGTC

AAAGCAGCTAGCCGTGTCTACGACACTGAGGCCAATCTTTCAGTGGAAAGTGAATTAACCATTTTTCCTGTGGAATCGAA

AGACATCTATCCAGATGGTTTGACAACAATTGCACCGATTTATGGTGGAGGTATGCGTCTAGGATCTCTTATCATTTGGC

GCAACGATAATGAGTTTAGTGATGAGGACCTCATCTTGGTTGAAATTTCAAGCACGGTTGTTGGGATTCAGTTGTTAAAC

CTTCAAACAGAAAACCTGGAAGAAACGATCCGCAAGCAAACTGCTGTCAACATGGCTATTAACACCCTATCTTATTCAGA

AATGAAGGCTGTTGCAGCTATTCTTGGTGAATTGGATGGTAACGAAGGGCGTTTAACAGCTTCTGTCATTGCTGACCGTA

TTGGCATTACACGATCTGTGATCGTCAATGCCCTTCGTAAATTGGAAAGTGCTGGTATTATTGAAAGTCGCTCTCTCGGC

ATGAAGGGAACCTACCTCAAAGTTATTAATGAGGGTATTTTTGATAAATTGAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A9X9SKT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
codY	Lactococcus lactis subsp. lactis strain DGCC12653	66.537	98.846	0.658
codY	Bacillus subtilis subsp. subtilis str. 168	53.036	95	0.504

Detailed information NTG0717434