Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   MGCS36083_RS00805 Genome accession   NZ_CP117285
Coordinates   129473..129718 (+) Length   81 a.a.
NCBI ID   WP_049519695.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 124473..134718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGCS36083_RS00780 (MGCS36083_00320) - 126380..126745 (+) 366 WP_003055257.1 DUF1033 family protein -
  MGCS36083_RS00785 (MGCS36083_00322) comGA/cglA 126826..127767 (+) 942 WP_014611930.1 competence type IV pilus ATPase ComGA Machinery gene
  MGCS36083_RS00790 (MGCS36083_00324) comGB 127703..128734 (+) 1032 WP_084916952.1 competence type IV pilus assembly protein ComGB Machinery gene
  MGCS36083_RS00795 (MGCS36083_00326) comGC 128736..129062 (+) 327 WP_084916953.1 competence type IV pilus major pilin ComGC Machinery gene
  MGCS36083_RS00800 (MGCS36083_00328) comGD 129037..129465 (+) 429 WP_257638821.1 competence type IV pilus minor pilin ComGD Machinery gene
  MGCS36083_RS00805 (MGCS36083_00330) comGE 129473..129718 (+) 246 WP_049519695.1 competence type IV pilus minor pilin ComGE Machinery gene
  MGCS36083_RS00810 (MGCS36083_00332) comGF 129699..130139 (+) 441 WP_003061780.1 competence type IV pilus minor pilin ComGF Machinery gene
  MGCS36083_RS00815 (MGCS36083_00334) comGG 130168..130491 (+) 324 WP_227985720.1 competence type IV pilus minor pilin ComGG -
  MGCS36083_RS00820 (MGCS36083_00336) comGH 130554..131507 (+) 954 WP_003060701.1 class I SAM-dependent methyltransferase Machinery gene
  MGCS36083_RS00825 (MGCS36083_00338) - 131566..132762 (+) 1197 WP_084916957.1 acetate kinase -
  MGCS36083_RS00830 (MGCS36083_00340) - 133069..133275 (+) 207 WP_003058508.1 helix-turn-helix transcriptional regulator -
  MGCS36083_RS00835 (MGCS36083_00342) - 133378..134058 (+) 681 WP_003060329.1 CPBP family intramembrane glutamic endopeptidase -
  MGCS36083_RS00840 (MGCS36083_00344) - 134076..134513 (+) 438 WP_012766452.1 hypothetical protein -

Sequence

Protein


Download         Length: 81 a.a.        Molecular weight: 9279.87 Da        Isoelectric Point: 10.2783

>NTDB_id=717364 MGCS36083_RS00805 WP_049519695.1 129473..129718(+) (comGE) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083]
MATGLLVAIVILVLTSLKQSQTRLTYYRSQQEKLNLALMAVQTGQASLNMNDYRLTVLRTEKTLIVRDQEGEVIRIEKKD
R

Nucleotide


Download         Length: 246 bp        

>NTDB_id=717364 MGCS36083_RS00805 WP_049519695.1 129473..129718(+) (comGE) [Streptococcus dysgalactiae subsp. equisimilis strain MGCS36083]
ATGGCAACAGGCCTCCTCGTGGCTATTGTCATACTGGTTCTAACGAGTTTGAAGCAAAGTCAGACAAGGTTGACATATTA
TCGCAGCCAACAAGAAAAGCTCAACCTAGCTCTGATGGCAGTACAAACTGGTCAAGCGTCTCTCAATATGAATGATTATC
GTCTGACGGTTTTACGCACAGAAAAAACACTTATCGTTAGGGATCAGGAAGGAGAAGTTATTAGAATTGAAAAAAAGGAC
AGGTAG

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(2-76)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

41.772

97.531

0.407
  comGE Streptococcus mutans UA159

41.772

97.531

0.407