Detailed information NTG0715868

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: NQ504_RS05135
• Genome accession: NZ_CP102284
• Coordinates: 1017378..1018202 (+)
• Length: 274 a.a.
• NCBI ID: WP_003698166.1
• Uniprot ID: E7FPE3
• Organism: Ligilactobacillus ruminis strain ATCC 25644
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1012378..1023202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQ504_RS05105 (NQ504_05105)	-	1012507..1012707 (-)	201	WP_004563576.1	hypothetical protein	-
NQ504_RS05110 (NQ504_05110)	-	1012820..1014058 (+)	1239	WP_151917794.1	IS256 family transposase	-
NQ504_RS05115 (NQ504_05115)	-	1014582..1015442 (-)	861	WP_003698159.1	helix-turn-helix domain-containing protein	-
NQ504_RS05120 (NQ504_05120)	-	1015729..1016310 (+)	582	WP_003698160.1	GNAT family N-acetyltransferase	-
NQ504_RS05125 (NQ504_05125)	-	1016373..1016813 (+)	441	WP_225430485.1	hypothetical protein	-
NQ504_RS10860	tnpB	1016713..1017066 (-)	354	WP_004563577.1	IS66 family insertion sequence element accessory protein TnpB	-
NQ504_RS05130 (NQ504_05130)	-	1017047..1017247 (-)	201	WP_004563576.1	hypothetical protein	-
NQ504_RS05135 (NQ504_05135)	endA	1017378..1018202 (+)	825	WP_003698166.1	DNA/RNA non-specific endonuclease	Machinery gene
NQ504_RS05140 (NQ504_05140)	-	1018294..1018941 (+)	648	WP_003698168.1	nitroreductase family protein	-
NQ504_RS05145 (NQ504_05145)	-	1018998..1019810 (+)	813	WP_003698169.1	endo alpha-1,4 polygalactosaminidase	-
NQ504_RS05150 (NQ504_05150)	-	1019960..1020511 (+)	552	WP_003698171.1	NUMOD4 domain-containing protein	-
NQ504_RS05155 (NQ504_05155)	-	1020563..1021240 (+)	678	WP_003698172.1	DUF3862 domain-containing protein	-

Sequence

Protein

• Length: 274 a.a.
• Molecular weight: 30539.93 Da
• Isoelectric Point: 9.7452

>NTDB_id=715868 NQ504_RS05135 WP_003698166.1 1017378..1018202(+) (endA) [Ligilactobacillus ruminis strain ATCC 25644]
MVKRRKQNKSFATLIIAIGLVLLSWTAFGKKIGLDEWLNSGGQSQTNRVQNDESTPERQLAESVLSDSIRQRLGQKIEWN
GHGAFIINDNKTDLNANVSSAPYAVNRKETGAMIGDAWLNRTTRQYKNRSETGQGRTDWRPQGFKQKLDLSGRYSHAYDR
GHLLAYALVGGLRGFDASEANPDNIATQTAWANEAQSANSTGQNYYEGLVRKALDQNERVRYRVTDLFEEGNLVPSGAHI
EAKSRSGSLEFNVFVPNVQKGIEINYQTGDVSVK

Nucleotide

• Length: 825 bp

>NTDB_id=715868 NQ504_RS05135 WP_003698166.1 1017378..1018202(+) (endA) [Ligilactobacillus ruminis strain ATCC 25644]
ATGGTCAAAAGAAGAAAACAAAACAAAAGCTTTGCGACCCTGATCATTGCCATCGGGTTGGTCCTGCTGAGCTGGACTGC
CTTCGGCAAAAAAATCGGCTTGGACGAGTGGCTGAATTCAGGAGGTCAATCTCAAACAAACCGCGTCCAAAACGACGAAA
GCACACCGGAAAGACAGCTTGCGGAAAGCGTTTTGAGCGATTCAATCAGACAAAGACTCGGACAGAAAATCGAGTGGAAC
GGACATGGAGCCTTCATCATCAATGATAACAAGACCGATTTGAATGCCAATGTTTCAAGTGCTCCGTATGCGGTCAACAG
AAAAGAAACCGGGGCGATGATCGGGGATGCCTGGCTGAACAGGACGACCAGACAATACAAAAATCGCAGTGAAACCGGCC
AAGGCAGGACCGACTGGCGCCCCCAGGGCTTCAAACAAAAACTTGATTTGAGCGGTCGCTACTCTCATGCTTACGACAGA
GGTCACTTGCTGGCTTATGCTTTGGTCGGGGGACTGAGAGGGTTTGACGCATCTGAAGCCAATCCCGACAATATCGCAAC
GCAGACGGCCTGGGCAAATGAGGCCCAAAGCGCAAATTCGACCGGTCAAAACTACTATGAAGGACTTGTCCGAAAAGCGC
TTGATCAAAACGAACGGGTTCGCTATCGAGTTACCGATTTGTTTGAAGAAGGCAATCTGGTTCCTTCCGGGGCGCACATT
GAGGCCAAAAGCAGATCGGGATCGCTTGAATTCAACGTGTTCGTGCCAAACGTTCAAAAGGGCATCGAAATCAATTACCA
AACCGGAGACGTCAGCGTCAAATAA

Domains

Predicted by InterProScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (122-247)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	58.228	86.496	0.504
endA	Streptococcus pneumoniae D39	58.228	86.496	0.504
endA	Streptococcus pneumoniae R6	58.228	86.496	0.504
endA	Streptococcus pneumoniae TIGR4	58.228	86.496	0.504