Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   NQZ98_RS00945 Genome accession   NZ_CP102135
Coordinates   146578..147531 (+) Length   317 a.a.
NCBI ID   WP_141599728.1    Uniprot ID   A0A540U5A3
Organism   Streptococcus suis strain M106471_S40     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 137689..147531 146578..147531 within 0


Gene organization within MGE regions


Location: 137689..147531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ98_RS00870 (NQZ98_00870) - 137689..138147 (-) 459 WP_024387081.1 hypothetical protein -
  NQZ98_RS00875 (NQZ98_00875) - 138151..138366 (-) 216 WP_228380969.1 hypothetical protein -
  NQZ98_RS00880 (NQZ98_00880) - 138415..138612 (-) 198 WP_228380148.1 hypothetical protein -
  NQZ98_RS00885 (NQZ98_00885) - 138609..139448 (-) 840 WP_024399985.1 ATP-binding protein -
  NQZ98_RS00890 (NQZ98_00890) - 139460..140304 (-) 845 Protein_140 phage replisome organizer N-terminal domain-containing protein -
  NQZ98_RS00895 (NQZ98_00895) - 140294..140572 (-) 279 WP_024399988.1 hypothetical protein -
  NQZ98_RS00900 (NQZ98_00900) - 140802..141047 (-) 246 WP_024399989.1 hypothetical protein -
  NQZ98_RS00905 (NQZ98_00905) - 141057..141269 (-) 213 WP_024399990.1 hypothetical protein -
  NQZ98_RS00910 (NQZ98_00910) - 141272..141475 (-) 204 WP_024387085.1 hypothetical protein -
  NQZ98_RS00915 (NQZ98_00915) - 141863..142153 (-) 291 WP_024387086.1 hypothetical protein -
  NQZ98_RS00920 (NQZ98_00920) - 142169..142786 (-) 618 WP_024392888.1 Rha family transcriptional regulator -
  NQZ98_RS00925 (NQZ98_00925) - 142936..143124 (-) 189 WP_024399991.1 DNA-binding protein -
  NQZ98_RS00930 (NQZ98_00930) - 143274..143972 (+) 699 WP_050571572.1 helix-turn-helix domain-containing protein -
  NQZ98_RS00935 (NQZ98_00935) - 144193..145083 (+) 891 WP_024399992.1 Abi family protein -
  NQZ98_RS00940 (NQZ98_00940) - 145336..146481 (+) 1146 WP_024399993.1 site-specific integrase -
  NQZ98_RS00945 (NQZ98_00945) comYH 146578..147531 (+) 954 WP_141599728.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35774.91 Da        Isoelectric Point: 4.4696

>NTDB_id=714563 NQZ98_RS00945 WP_141599728.1 146578..147531(+) (comYH) [Streptococcus suis strain M106471_S40]
MNFEKIEQAYDLLLENVQTIQNQLGTNIYDAMIEQNAAYVADQHETDLVVNNNKTLKQLDLTKEEWRRAYQFLLIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLVPTQKVTVLEIGSGTGNLAQTILNASQKELDYLGIEVDDLLIDLSASIADVMQAD
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPKEHTYAHHLLMEQSLKYLEKDGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIIAMIALPPNLFGKAAMAKSIFVLQKKAARSLTPFVYPLQSLQEPEAIQKFMLNFKNWKQENAI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=714563 NQZ98_RS00945 WP_141599728.1 146578..147531(+) (comYH) [Streptococcus suis strain M106471_S40]
ATGAATTTTGAAAAGATCGAACAGGCTTACGACCTGCTATTAGAAAACGTACAGACTATCCAAAACCAGCTAGGTACCAA
TATCTATGATGCCATGATTGAGCAAAATGCTGCTTACGTAGCTGATCAGCATGAGACGGACCTTGTTGTCAATAATAACA
AGACCTTGAAGCAACTAGATTTAACCAAGGAAGAATGGCGTCGTGCCTATCAATTCTTGCTCATCAAGGCCAATCAGACT
GAGCCCATGCAGTACAATCACCAGTTCACACCAGATTCTATCGGATTTATCCTATCTTTTCTAGTAGACCAATTGGTGCC
GACTCAAAAGGTGACAGTTCTGGAAATTGGTTCGGGGACAGGCAATCTAGCTCAGACCATTCTCAACGCCAGCCAGAAAG
AATTGGATTACTTGGGGATCGAAGTGGACGACCTCTTGATTGATTTGTCGGCAAGTATTGCGGATGTCATGCAGGCAGAT
ATTTCTTTTGCTCAGGGAGATGCGGTACGTCCGCAGATTTTGAAGGAAAGTCAAGTAATTCTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGTTATCAGGTCGCCAGTCCAAAGGAACATACCTACGCCCATCATTTACTCA
TGGAACAATCCCTCAAATATCTGGAAAAAGATGGCTTTGCGATTTTGTTGGCTCCAAATGATTTATTGACTAGTCCGCAA
AGCGATTTGCTGAAAGGTTGGTTACAGGAGCAAGCCAATATTATTGCCATGATTGCCCTGCCACCAAATCTCTTTGGGAA
GGCTGCTATGGCCAAGTCTATTTTTGTCTTGCAAAAGAAAGCTGCAAGATCGTTGACGCCGTTTGTTTATCCCTTGCAAA
GTCTTCAAGAACCAGAAGCTATTCAGAAGTTCATGCTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A540U5A3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

60.759

99.685

0.606
  comYH Streptococcus mutans UA159

60.443

99.685

0.603