Detailed information NTG0711219

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: NN994_RS05310
• Genome accession: NZ_CP101646
• Coordinates: 1006933..1007814 (-)
• Length: 293 a.a.
• NCBI ID: WP_014621666.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain UCCSt95
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1001933..1012814

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NN994_RS05285 (NN994_05285)	vicR	1002639..1003346 (-)	708	WP_011681206.1	response regulator YycF	Regulator
NN994_RS05290 (NN994_05290)	-	1003872..1004639 (+)	768	WP_064355894.1	amino acid ABC transporter ATP-binding protein	-
NN994_RS05295 (NN994_05295)	-	1004651..1005484 (+)	834	WP_002953142.1	transporter substrate-binding domain-containing protein	-
NN994_RS05300 (NN994_05300)	-	1005502..1006200 (+)	699	WP_014608374.1	amino acid ABC transporter permease	-
NN994_RS05305 (NN994_05305)	-	1006212..1006862 (+)	651	WP_064355893.1	amino acid ABC transporter permease	-
NN994_RS05310 (NN994_05310)	endA	1006933..1007814 (-)	882	WP_014621666.1	DNA/RNA non-specific endonuclease	Machinery gene
NN994_RS05315 (NN994_05315)	-	1007876..1008064 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-
NN994_RS05320 (NN994_05320)	murA	1008066..1009337 (-)	1272	WP_064355891.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
NN994_RS05325 (NN994_05325)	-	1009407..1009643 (-)	237	WP_064355890.1	DUF1146 family protein	-
NN994_RS05330 (NN994_05330)	galE	1009831..1010844 (-)	1014	WP_064355887.1	UDP-glucose 4-epimerase GalE	-
NN994_RS05335 (NN994_05335)	-	1010859..1011314 (-)	456	WP_064355886.1	DUF4832 domain-containing protein	-

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 31818.50 Da
• Isoelectric Point: 10.0477

>NTDB_id=711219 NN994_RS05310 WP_014621666.1 1006933..1007814(-) (endA) [Streptococcus thermophilus strain UCCSt95]
MVERKTSLTNKQKRQLVTLIIAALIAVLGYLGTSNKLSPDNPIRQVASLVSGKSNKSIKSNGSTNSQSTPQEQLSETVMT
SSVKSQLGNSLEWNGAGAYIINRNKTNLNAKVSSQPYANNQVKTVQGQTVPTVANALLSKATRQYKNRQETGNGSTSWTP
AGWHQVQNLSGEYSHAVDRGHLLGYALIGGLKGFDASTSNPENIAVQTAWANQAYSDSSTGQNYYESLVRKALDKNKRVR
YRVTLIYEGENLIPSGTHLEAKSADGSLEFNVFVPNVQEGITLDYYSGKVTVN

Nucleotide

• Length: 882 bp

>NTDB_id=711219 NN994_RS05310 WP_014621666.1 1006933..1007814(-) (endA) [Streptococcus thermophilus strain UCCSt95]
ATGGTAGAAAGAAAGACATCTTTGACAAATAAACAGAAACGTCAGTTAGTCACATTAATAATAGCAGCTTTAATAGCTGT
TTTAGGTTACCTAGGAACCAGTAACAAGCTCTCGCCTGATAATCCTATCAGACAAGTAGCAAGCCTAGTTTCAGGGAAAT
CTAACAAATCCATTAAATCTAATGGTTCAACAAATAGTCAGTCTACACCACAAGAGCAGCTTTCTGAGACAGTAATGACT
AGTTCAGTCAAAAGCCAACTGGGTAATTCCTTGGAATGGAATGGAGCTGGGGCCTACATTATTAATAGAAATAAGACGAA
TCTAAATGCTAAGGTATCAAGCCAACCCTATGCTAATAACCAAGTCAAAACGGTTCAAGGACAAACTGTTCCTACAGTTG
CTAATGCCTTATTAAGTAAAGCAACTAGACAGTACAAAAATCGTCAAGAAACAGGGAATGGTTCAACCTCTTGGACACCA
GCTGGATGGCACCAGGTTCAAAATTTATCAGGAGAGTATAGCCATGCCGTAGATAGAGGCCATTTGCTAGGTTATGCACT
GATAGGTGGTTTGAAAGGATTTGACGCCTCGACTTCAAATCCAGAGAATATTGCTGTTCAAACTGCTTGGGCAAATCAAG
CATATAGCGATAGTTCTACAGGCCAAAACTATTATGAAAGCCTAGTACGAAAAGCTCTGGATAAAAACAAACGTGTTCGT
TATCGTGTGACCTTGATTTATGAAGGAGAGAATCTCATTCCATCAGGAACACATCTTGAAGCTAAGTCAGCAGACGGCTC
ACTTGAGTTTAATGTCTTTGTTCCAAATGTACAAGAGGGAATTACACTAGATTACTATTCAGGAAAAGTAACGGTGAATT
GA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (101-266)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	72.385	81.57	0.59
endA	Streptococcus pneumoniae D39	72.385	81.57	0.59
endA	Streptococcus pneumoniae R6	72.385	81.57	0.59
endA	Streptococcus pneumoniae TIGR4	72.385	81.57	0.59